Project description
Novel single-molecule bioelectronic system for clinical biomarker detection
Enabling the detection of several biomarkers simultaneously will improve the sensitivity of tests and diagnostic conclusions. Moreover, biomarkers should be detected with the highest possible analytical sensitivity as they are typically not present in cell populations, and one single molecule can reveal the onset of a pathological state. The EU-funded SiMBiT project aims to develop a bioelectronic system to enable single-molecule detection of both proteins and DNA biomarkers. The objective is the development of a lab-based and cost-effective portable multiplexing array prototype that produces fast results. SiMBiT will be employed for the early detection of human pancreatic neoplasms, performing simultaneous analysis of genomic and protein markers with a minimal sample volume.
Fields of science
- natural sciencesbiological sciencesgeneticsDNA
- natural sciencesbiological sciencesbiochemistrybiomoleculesproteins
- engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensors
- medical and health sciencesclinical medicineoncologypancreatic cancer
Programme(s)
Funding Scheme
RIA - Research and Innovation actionCoordinator
50019 Firenze
Italy
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Participants (9)
40225 Dusseldorf
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25121 Brescia
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20500 Abo
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16163 Genova
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5612 AE Eindhoven
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Participation ended
CB4 0FX Cambridge
70026 Modugno
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
06410 Biot
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CB4 0FX Cambridge
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.