Endocrine-disrupting chemicals and female reproductive health assessment
The EU-funded FREIA project aims to develop test methods to identify human-made endocrine-disrupting chemicals (EDCs) and their effects on the female reproductive system. Current safety tests often overlook the impact of EDCs, meaning that women's reproductive health is at risk globally. The FREIA consortium has developed human tissue models representing the entire life cycle, from fetal ovarian and adrenal tissues to mature ovarian follicles, to identify biomarkers of EDC exposure. Research integrates the data from in vitro studies with primary human tissues, human exposure data from fetal and follicular fluid samples, and in vitro and in vivo research findings. The FREIA project is well-positioned to accumulate novel information on EDC-related reproductive health risks to improve women's reproductive health around the world.
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