Project description
3D thyroid gland models for screening endocrine disruptors
Three-dimensional (3D) cell assays more faithfully mimic the structure and function of native tissue, offering better test-models for biology, biochemistry and drug discovery studies. The EU-funded SCREENED project is working on native thyroid gland organoids, decellularised scaffolds or bioprinted constructs that house tissue-specific cells. Using these assays, researchers are investigating the effect of endocrine-disrupting chemicals on thyroid function offering a mechanistic understanding of their mode of action. Results will validate the sensitivity and specificity of these in vitro assays compared to existing 2D cell cultures and animal models.
Programme(s)
Topic(s)
Funding Scheme
RIA - Research and Innovation actionCoordinator
6200 MD Maastricht
Netherlands
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Participants (8)
43100 Parma
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1050 Bruxelles
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00185 Roma
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93053 Regensburg
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
4 Dublin
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V94 W5TV Limerick Clare
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
75008 Paris
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OX14 4RZ Abingdon Oxfordshire
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