Deliverables Documents, reports (2) Transcriptomic datasets of effect of EDs on thyroid cells This deliverable consists of a report describing the transcriptomic data obtained in the 3D in vitro models. Proteomic and datasets of effect of EDs on thyroid cells This deliverable consists of a report describing the proteomics data obtained in the 3D in vitro models. Websites, patent fillings, videos etc. (2) Individualised press release for every partner Edition of one press release to communicate about the project objectives, approach and results. The press release will be translated into the language of each partner country. Launch of public website & Twitter account SCREENED website with project information, news and results allowing interactions with third parties. Publications Thesis and dissertations (2) Liquid chromatography – mass spectrometry, biomaterials and 3D printing in analytical applications Author(s): Giulia Remaggi Published in: PhD Thesis, 2023 Publisher: University of Parma, Italy "An innovative European Joint Research Center-submitted in vitro assay for screening Endocrine Disruptors effects on thyroid cell function: Horizon Project SCREENED #825745" Author(s): Elena Caddeo Published in: PhD Thesis, 2023 Publisher: University of Parma, Italy Conference proceedings (2) Generation of human thyroid organoids from embryonic stem cells to rescue hypothyroidism Author(s): Mírian Romitti, Adrien Tourneur, Barbara de Faria da Fonseca, Gilles Doumont, Pierre Gillotay, Xiao-Hui Liao, Sema Elif Eski, Gaetan Van Simaeys, Laura Chomette, Helene Lasolle, Olivier Monestier, Dominika Figini Kasprzyk, Vincent Detours, Sumeet Pal Singh, Serge Goldman, Samuel Refetoff & Sabine Costagliola Published in: European Thyroid Association Congress, Issue September, 2022, 2022 Publisher: ETA Insulin orchestrates thyroid and lung cell lineage divergence in human stem cell-derived organoids Author(s): Mírian Romitti, Adrien Tourneur, Barbara de Faria da Fonseca, Gilles Doumont, Pierre Gillotay, Xiao-Hui Liao, Sema Elif Eski, Gaetan Van Simaeys, Laura Chomette, Helene Lasolle, Olivier Monestier, Dominika Figini Kasprzyk, Vincent Detours, Sumeet Pal Singh, Serge Goldman, Samuel Refetoff & Sabine Costagliola Published in: 19th International Congress of Developmental Biology, Issue October, 2022, 2022 Publisher: International Society of Developmental Biologists Peer reviewed articles (8) Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism Author(s): Mírian Romitti, Adrien Tourneur, Barbara de Faria da Fonseca, Gilles Doumont, Pierre Gillotay, Xiao-Hui Liao, Sema Elif Eski, Gaetan Van Simaeys, Laura Chomette, Helene Lasolle, Olivier Monestier, Dominika Figini Kasprzyk, Vincent Detours, Sumeet Pal Singh, Serge Goldman, Samuel Refetoff & Sabine Costagliola Published in: Nature Communications, Issue November, 2022, 2022, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-022-34776-7 CODA: a combo-Seq data analysis workflow Author(s): Marta Nazzari, Duncan Hauser, Marcel van Herwijnen, Mírian Romitti, Daniel J Carvalho, Anna M Kip, and Florian Caiment Published in: Briefings in Bioinformatics, Issue 24, January 2023, 2023, Page(s) 1, ISSN 1477-4054 Publisher: Oxford University Press DOI: 10.1093/bib/bbac582 A Computational Template for Three-Dimensional Modeling of the Vascular Scaffold of the Human Thyroid Gland Author(s): Giulia Spaletta; Mark Sofroniou; Fulvio Barbaro; Giusy di Conza; Salvatore Mosca; Roberto Toni Published in: Tissue Engineering Part A, Issue Volume 29, Numbers 1 and 2, 2023, 2023, Page(s) 47-57, ISSN 1937-335X Publisher: Mary Ann Liebert, Inc. DOI: 10.1089/ten.tea.2022.0148 SCREENED: A Multistage Model of Thyroid Gland Function for Screening Endocrine-Disrupting Chemicals in a Biologically Sex-Specific Manner Author(s): Lorenzo Moroni, Fulvio Barbaro, Florian Caiment, Orla Coleman, Sabine Costagliola, Giusy Di Conza, Lisa Elviri, Stefan Giselbrecht, Christian Krause, Carlos Mota, Marta Nazzari, Stephen R. Pennington, Annette Ringwald, Monica Sandri, Simon Thomas, James Waddington, Roberto Toni Published in: International Journal of Molecular Sciences, Issue 21/10, 2020, Page(s) 3648, ISSN 1422-0067 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms21103648 A targeted mass spectrometry method to screen collagen types I-V in the decellularized 3D extracellular matrix of the adult male rat thyroid Author(s): Marco Alfieri, Fulvio Barbaro, Elia Consolini, Elena Bassi, Davide Dallatana, Carlo Bergonzi, Annalisa Bianchera, Ruggero Bettini, Roberto Toni, Lisa Elviri Published in: Talanta, Issue 193, 2019, Page(s) 1-8, ISSN 0039-9140 Publisher: Elsevier BV DOI: 10.1016/j.talanta.2018.09.087 Decellularization detergents as methdological variables in mass spectrometry of stromal matrices Author(s): Giulia Remaggi, Fulvio Barbaro, Giusy Di Conza, Giovanna Trevisi, Carlo Bergonzi Published in: Tissue Egineering Part C Methods, Issue Volume 28, Number 4, 2022, 2022, Page(s) 148 - 157, ISSN 1937-3384 Publisher: Mary Ann Liebert Inc. DOI: 10.1089/ten.tec.2021.0191 Thyroid-on-a-chip: An organoid Platform for in vitro assessment of endocrine disruption Author(s): Daniel J. Carvalho, Anna M. Kip, Mírian Romitti, Marta Nazzari, Andreas Tegel, Matthias Stich, Christian Krause, Florian Caiment, Sabine Costagliola, Lorenzo Moroni, Stefan Giselbrecht Published in: Advances Healthcare Materials, Issue 12.8, March 2023, 2023, ISSN 1521-4095 Publisher: Wiley DOI: 10.1002/adhm.202201555 Investigation of the effects of phthalates on in vitro thyroid models with RNA-Seq and ATAC-Seq Author(s): Marta Nazzari, Mírian Romitti, Duncan Hauser, Daniel J. Carvalho, Stefan Giselbrecht, Lorenzo Moroni, Sabine Costagliola, Florian Caiment Published in: Frontiers in Endocrinology, Issue 14, 2023, 2023, ISSN 1664-2392 Publisher: Frontiers Media S.A DOI: 10.3389/fendo.2023.1200211 Non-peer reviewed articles (1) Clamping strategies for organ-on-a-chip devices Author(s): Daniel J. Carvalho, Lorenzo Moroni, Stefan Giselbrecht Published in: Nature Reviews Materials, Issue 19, January 2023, 2023, ISSN 1476-4687 Publisher: Nature DOI: 10.1038/s41578-022-00523-z Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available