Project description DEENESFRITPL Strategies for early screening and prevention of cervical cancer in hard-to-reach populations Cervical cancer is the fourth most common cancer in women, and the hard-to-reach populations in many countries are at a higher risk of developing the disease. Preventive screening programmes and vaccination against human papillomavirus (HPV) result in reduced cancer incidence and mortality. The EU-funded ELEVATE project is conducting studies to identify hard-to-reach women in Belgium, Brazil, Ecuador and Portugal in order to remove barriers to their early screening and design strategies to make it more accessible. A multidisciplinary team of experts from Europe and the Community of Latin American and Caribbean States are carrying out the fundamental and technological research to develop an efficient and marketable test for the detection of high-risk HPV infections in those populations. The goal is to design a portable test compatible with self-sampling, generating rapid and easy-to-understand results. Show the project objective Hide the project objective Objective Cervical cancer is the 4th most common cancer in women worlThe ELEVATE project sets a multidisciplinary team comprising manufactures and experts from Europe and the Community of Latin American and Caribbean States, to improve the global adequacy and coverage of cervical cancer screening, particularly to specific populations of women that by not being regularly screened (hard-to-reach populations) are at higher-risk to develop cervical cancer. Although Cervical cancer is still the fourth most common cancer in women worldwide, with up to 85% of the burden occurring in developing countries, preventive vaccination against human papillomavirus and early detection of precancer in screening programs has shown to be successful in reducing cancer incidence and mortality.1–3 However, different challenges hamper a global implementation of such programs and are in the base of women’s non-attendance to screening. This highlights the lack of reflection of ethnic, cultural and resource differences from different populations in current cervical cancer screening. In ELEVATE it is proposed to conduct social science investigations to identify hard-to-reach women in Belgium, Brazil, Ecuador and Portugal, to address their barriers to screening and to design strategies to make primary screening more accessible to them, and therefore, contribute to reduce the global burden of cervical cancer. This will be complemented with fundamental and technological research to develop an efficient and marketable test for the combined genomic and proteomic detection of high-risk HPV infections in those populations. The test will be made portable, low-cost, compatible with self-sampling, point-of-care and generate rapid and easy-to-understand results, without relying on electrical outlets or trained health personnel. Integrant part of the proposal is also to infer and disseminate the societal, economic implications of the developed strategies using a hard-to-reach community-based participatory research. Fields of science social sciencessociologydemographymortalitymedical and health sciencesclinical medicineoncologycervical cancermedical and health scienceshealth sciencesinfectious diseasesDNA viruses Programme(s) H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being Main Programme H2020-EU.3.1.3. - Treating and managing disease Topic(s) SC1-BHC-18-2018 - Translational collaborative cancer research between Europe and the Community of Latin American and Caribbean States (CELAC) Call for proposal H2020-SC1-BHC-2018-2020 See other projects for this call Sub call H2020-SC1-2018-Single-Stage-RTD Funding Scheme RIA - Research and Innovation action Coordinator UNIVERSITEIT GENT Net EU contribution € 1 518 835,00 Address Sint pietersnieuwstraat 25 9000 Gent Belgium See on map Region Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Participants (8) Sort alphabetically Sort by Net EU contribution Expand all Collapse all UNIVERSIDADE NOVA DE LISBOA Portugal Net EU contribution € 419 850,00 Address Campus de campolide 1099 085 Lisboa See on map Region Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 CONSORCIO DE INVESTIGACION SOBRE VIH SIDA TB CISIDAT Mexico Net EU contribution € 0,00 Address Av. teopanzolco 408 torre c 201 reforma 62260 Cuernavaca morelos See on map Activity type Research Organisations Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 186 820,00 UNIVERSIDAD DE CUENCA Ecuador Net EU contribution € 259 900,00 Address 12 of april avenue 01.01 Cuenca See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 FUNDACAO PIO XII Brazil Net EU contribution € 0,00 Address Rua antenor duarte vilela, 1331 Barretos See on map Activity type Research Organisations Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 510 500,00 UNIVERSITAT ROVIRA I VIRGILI Spain Net EU contribution € 341 802,50 Address Carrer de escorxador 43003 Tarragona See on map Region Este Cataluña Tarragona Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV Germany Net EU contribution € 214 577,50 Address Hansastrasse 27c 80686 Munchen See on map Region Bayern Oberbayern München, Kreisfreie Stadt Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 LABMAN AUTOMATION LIMITED United Kingdom Net EU contribution € 395 420,00 Address Seamer hill stokesley TS9 5NQ Middlesbrough cleveland See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Yorkshire and the Humber North Yorkshire North Yorkshire CC Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 MICROLIQUID SL Spain Net EU contribution € 151 605,00 Address Avenida uribarri 19-1 saiolan 20500 Arrasate mondragon See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Noreste País Vasco Gipuzkoa Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00