Deliverables
Testing 800 FFPE and serology material
SOPs for FFPE tissue accession sectioning, tissue array processing, and storage to be available on the website
SOPs for FFPE tissue accession sectioning, tissue array processing, and storage will be available to all members on the HEADSpAcE project website
Updated report on biorepository availabilityAnnual report on biorepository availability including new recruitment and followup
Statistical analyses reportsStatistical analyses reports comparing HPV analysis region lifestyle and clinical factors
Workshop on HPV16 E6 ELISA assayA 2-day hands-on workshop on HPV16 E6 ELISA assay for all WP3 participating centers will be organized in Heidelberg
Report of second scientific meetingReport of second scientific meeting of HEADSpAcE
Workshop on tissue array processing and good practices in IHC techniquesA 2-day workshop on tissue array processing and good practices in IHC techniques for all HEADSpAcE participating centers will be organized in Bogotá, in particular for clinical institutions with pathology services
Protocol for prospective recruitment of 1100 HNC cases in Europe and SASelection of 800 cases for comprehensive genomic analysis
Selection of 800 cases for comprehensive genomic analysis including 200 cases from Europe and 600 from South America
Updated report on communication strategyUpdated report on the communication strategy at M66
Annual report on the communication strategyAnnual report on the communication strategy on M12, M24, M36, and M48
Report of first scientific meetingReport of first scientific meeting of HEADSpAcE
Development of protocol for patient interviewsDevelopment of protocol for patient interviews to obtain information of reasons for delay in diagnosis
Annual report on biorepository availabilityAnnual report on biorepository availability, including new recruitment and follow-up. Will be due on M12, M24, M36, and M48.
Report on in-depth comparison between two centres on infrastructure causes of delay to diagnosisReport on indepth comparison between two centres on infrastructure causes of delay to diagnosis
SOPs for plasma collection, processing, and storage on the websiteSOPs for plasma collection, processing, and storage will be available to all members on the HEADSpAcE project website
Development of a reference standard for HPV16 E6Development of a reference standard for HPV16 E6 for international harmonization of HPV16 E6 serology
Development of ethics guidelines, documents and proceduresDevelopment of ethics guidelines, documents and procedures. Ethics guidelines will be developed by M3. Rules of data protection will be established at inception. The ethics guidelines will be posted in the website and regularly monitored
Summary of sample management systems available in centers with HNC biorepositoriesSummary of sample management systems available in centers with HNC biorepositories, ensuring compatibility of all systems
Development of project website. Website will be subsequently updated regularly when new reports,documents,outcome will become available
Data management plan including the organisation and coordination of biosample and data sharing between partner institutes
Publications
Author(s):
Kelten Clements, Alekh Thapa, Anna Cowell, David Conway, Catriona M Douglas, Claire Paterson
Published in:
Clinical Otolaryngology, Issue 49, 2024, Page(s) 363-375, ISSN 1749-4478
Publisher:
Blackwell Publishing Inc.
DOI:
10.1111/coa.14152
Author(s):
Maja Popovic, Valentina Fiano, Giovenale Moirano, Luigi Chiusa, David I. Conway, Paolo Garzino Demo, Marco Gilardetti, Giuseppe Carlo Iorio, Chiara Moccia, Oliviero Ostellino, Giancarlo Pecorari, Guglielmo Ramieri, Umberto Ricardi, Giuseppe Riva, Shama Virani, Lorenzo Richiardi
Published in:
Frontiers in public health, Issue 21 Feb 2022, 2022, Page(s) 1-10, ISSN 2296-2565
Publisher:
Frontiers Media
DOI:
10.3389/fpubh.2022.809283
Author(s):
Josefina Martínez‐Ramírez, Cristina Saldivia‐Siracusa, Leonor‐Victoria González‐Pérez, Florence Juana Maria Cuadra Zelaya, Roberto Gerber‐Mora, Osmani Fabricio Guevara Cabrera, Ronell Bologna‐Molina, Gerardo Gilligan, Wilson Delgado‐Azañero, Arvind Babu Rajendra Santosh, Wilfredo Alejandro González‐Arriagada, Mariana Villarroel‐Dorrego, Bernardo Venegas Rojas, Karen Patri
Published in:
Oral Diseases, Issue 21 Feb 2024, 2024, ISSN 1354-523X
Publisher:
Wiley-Blackwell
DOI:
10.1111/odi.14903
Author(s):
Lady Paola Aristizabal Arboleda, Genival Barbosa de Carvalho, Alan Roger Santos-Silva, Gisele Aparecida Fernandes, Jose Guilherme Vartanian, David I. Conway, Shama Virani, Paul Brennan, Luiz Paulo Kowalski, and Maria Paula Curado
Published in:
Cancers, Issue 3 Sep 2023, 2023, Page(s) 1-13, ISSN 2072-6694
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/cancers15174405
Author(s):
Kelten Clements, Anna Cowell, Gillian White, William Flynn, David I. Conway, Catriona M. Douglas, Claire Paterson
Published in:
Clinical Otolaryngology, Issue 16 March 2023, 2023, Page(s) 587-594, ISSN 1749-4486
Publisher:
Wiley-Blackwell
DOI:
10.1111/coa.14048
Author(s):
Paola Fernandes Pansini, Isabella Bittencourt do Valle, Thabata Coeli Dias Damasceno, Priscila Marinho de Abreu, Anna Clara Gregório Có, Rossana Verónica Mendoza López, Jeferson Lenzi, Ricardo Mai Rocha, Evandro Duccini Souza, Maria Paula Curado, Hisham Mehanna, Paul Nankivell, José Roberto Vasconcelos de Podestá, Sandra Ventorin von Zeidler.
Published in:
Head and neck pathology, Issue 11 April 2021, 2021, Page(s) 1127–1136, ISSN 1936-0568
Publisher:
Secaucus, NJ : Humana Press
DOI:
10.1007/s12105-021-01322-8
Author(s):
Mark Gormley, Grant Creaney, Andrew Schache, Kate Ingarfield, David I Conway
Published in:
British Dental Journal, Issue 11 November 2022, 2022, ISSN 1476-5373
Publisher:
Nature Portfolio
DOI:
10.1038/s41415-022-5166-x
Author(s):
Grant Creaney, Alex D. McMahon, Alastair J. Ross, Lesley A. Bhatti, Claire Paterson, and David I. Conway
Published in:
British Dental Journal, Issue 11 November 2022, 2022, Page(s) 787-793, ISSN 1476-5373
Publisher:
Nature Portfolio
DOI:
10.1038/s41415-022-5151-4
Author(s):
Aida Ferreiro-Iglesias; James McKay; Nicole Brenner; Shama Virani; Corina Lesseur; Corina Lesseur; Valerie Gaborieau; Andy R Ness; Andy R Ness; Rayjean J. Hung; Geoffrey Liu; Brenda Diergaarde; Andrew F. Olshan; Neil Hayes; Mark C. Weissler; Lea Schroeder; Noemi Bender; Michael Pawlita; Steve Thomas; Miranda Pring; Tom Dudding; Beatriz Kanterewicz; Robert L. Ferris; Sera Thomas; Yonathan Brhane; V
Published in:
Nature Communications, Issue 12 October 2021, 2021, Page(s) 1-11, ISSN 2041-1723
Publisher:
Nature Publishing Group
DOI:
10.1038/s41467-021-26151-9
Author(s):
Craig D. L. Smith, Alex D. McMahon, Donald M. Lyall, Mariel Goulart, Gareth J. Inman, Al Ross, Mark Gormley, Tom Dudding, Gary J. Macfarlane, Max Robinson, Lorenzo Richiardi, Diego Serraino, Jerry Polesel, Cristina Canova, Wolfgang Ahrens, Claire M. Healy, Pagona Lagiou, Ivana Holcatova, Laia Alemany, Ariana Znoar, Tim Waterboer, Paul Brennan, Shama Virani, David I. Conway
Published in:
Head & Neck, Issue 46, 2024, Page(s) 2261-2273, ISSN 1043-3074
Publisher:
John Wiley & Sons Inc.
DOI:
10.1002/hed.27834
Author(s):
Leandro Luongo Matos, Luiz Paulo Kowalski, Aline Lauda Freitas Chaves, Thiago Bueno de Oliveira, Gustavo Nader Marta, Maria Paula Curado, Gilberto de Castro Junior, Terence P. Farias, Gustavo Sarria Bardales, Mario Avila Cabrera, Renato de Castro Capuzzo, Genival Barbosa de Carvalho, Claudio Roberto Cernea, Rogério Aparecido Dedivitis, Fernando Luiz Dias, Andrés Munyo Estefan, Agustin Horacio Fa
Published in:
JCO Global Oncology, Issue 10 April 2024, 2024, ISSN 2687-8941
Publisher:
Lippincott Williams & Wilkins
DOI:
10.1200/go.23.00343
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