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Translational studies of HEAD and neck cancer in South America and Europe

Deliverables

Development of communication strategy

Development of communication strategy

SOPs for FFPE tissue accession sectioning, tissue array processing, and storage to be available on the website

SOPs for FFPE tissue accession sectioning, tissue array processing, and storage will be available to all members on the HEADSpAcE project website

Workshop on HPV16 E6 ELISA assay

A 2-day hands-on workshop on HPV16 E6 ELISA assay for all WP3 participating centers will be organized in Heidelberg

Workshop on tissue array processing and good practices in IHC techniques

A 2-day workshop on tissue array processing and good practices in IHC techniques for all HEADSpAcE participating centers will be organized in Bogotá, in particular for clinical institutions with pathology services

Protocol for prospective recruitment of 1100 HNC cases in Europe and SA

Protocol for prospective recruitment of 1100 HNC cases in Europe and SA

Selection of 800 cases for comprehensive genomic analysis

Selection of 800 cases for comprehensive genomic analysis including 200 cases from Europe and 600 from South America

Annual report on the communication strategy

Annual report on the communication strategy on M12, M24, M36, and M48

Development of protocol for patient interviews

Development of protocol for patient interviews to obtain information of reasons for delay in diagnosis

Annual report on biorepository availability

Annual report on biorepository availability, including new recruitment and follow-up. Will be due on M12, M24, M36, and M48.

SOPs for plasma collection, processing, and storage on the website

SOPs for plasma collection, processing, and storage will be available to all members on the HEADSpAcE project website

Development of ethics guidelines, documents and procedures

Development of ethics guidelines, documents and procedures. Ethics guidelines will be developed by M3. Rules of data protection will be established at inception. The ethics guidelines will be posted in the website and regularly monitored

Summary of sample management systems available in centers with HNC biorepositories

Summary of sample management systems available in centers with HNC biorepositories, ensuring compatibility of all systems

Development of project website

Development of project website. Website will be subsequently updated regularly when new reports,documents,outcome will become available

Data management plan

Data management plan including the organisation and coordination of biosample and data sharing between partner institutes