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CORDIS - Forschungsergebnisse der EU
CORDIS

Translational studies of HEAD and neck cancer in South America and Europe

Leistungen

Development of communication strategy
Testing 800 FFPE and serology material
SOPs for FFPE tissue accession sectioning, tissue array processing, and storage to be available on the website

SOPs for FFPE tissue accession sectioning, tissue array processing, and storage will be available to all members on the HEADSpAcE project website

Updated report on biorepository availability

Annual report on biorepository availability including new recruitment and followup

Statistical analyses reports

Statistical analyses reports comparing HPV analysis region lifestyle and clinical factors

Workshop on HPV16 E6 ELISA assay

A 2-day hands-on workshop on HPV16 E6 ELISA assay for all WP3 participating centers will be organized in Heidelberg

Report of second scientific meeting

Report of second scientific meeting of HEADSpAcE

Workshop on tissue array processing and good practices in IHC techniques

A 2-day workshop on tissue array processing and good practices in IHC techniques for all HEADSpAcE participating centers will be organized in Bogotá, in particular for clinical institutions with pathology services

Protocol for prospective recruitment of 1100 HNC cases in Europe and SA
Selection of 800 cases for comprehensive genomic analysis

Selection of 800 cases for comprehensive genomic analysis including 200 cases from Europe and 600 from South America

Updated report on communication strategy

Updated report on the communication strategy at M66

Annual report on the communication strategy

Annual report on the communication strategy on M12, M24, M36, and M48

Report of first scientific meeting

Report of first scientific meeting of HEADSpAcE

Development of protocol for patient interviews

Development of protocol for patient interviews to obtain information of reasons for delay in diagnosis

Annual report on biorepository availability

Annual report on biorepository availability, including new recruitment and follow-up. Will be due on M12, M24, M36, and M48.

Report on in-depth comparison between two centres on infrastructure causes of delay to diagnosis

Report on indepth comparison between two centres on infrastructure causes of delay to diagnosis

SOPs for plasma collection, processing, and storage on the website

SOPs for plasma collection, processing, and storage will be available to all members on the HEADSpAcE project website

Development of a reference standard for HPV16 E6

Development of a reference standard for HPV16 E6 for international harmonization of HPV16 E6 serology

Development of ethics guidelines, documents and procedures

Development of ethics guidelines, documents and procedures. Ethics guidelines will be developed by M3. Rules of data protection will be established at inception. The ethics guidelines will be posted in the website and regularly monitored

Summary of sample management systems available in centers with HNC biorepositories

Summary of sample management systems available in centers with HNC biorepositories, ensuring compatibility of all systems

Development of project website

Development of project website. Website will be subsequently updated regularly when new reports,documents,outcome will become available

Data management plan

Data management plan including the organisation and coordination of biosample and data sharing between partner institutes

Veröffentlichungen

The Impact of the COVID-19 Pandemic on Head and Neck Cancer Diagnosis in the Piedmont Region, Italy: Interrupted Time-Series Analysis

Autoren: Maja Popovic, Valentina Fiano, Giovenale Moirano, Luigi Chiusa, David I. Conway, Paolo Garzino Demo, Marco Gilardetti, Giuseppe Carlo Iorio, Chiara Moccia, Oliviero Ostellino, Giancarlo Pecorari, Guglielmo Ramieri, Umberto Ricardi, Giuseppe Riva, Shama Virani, Lorenzo Richiardi
Veröffentlicht in: Frontiers in public health, Ausgabe 21 Feb 2022, 2022, Seite(n) 1-10, ISSN 2296-2565
Herausgeber: Frontiers Media
DOI: 10.3389/fpubh.2022.809283

Squamous Cell Carcinoma of the Oral Cavity, Oropharynx, and Larynx: A Scoping Review of Treatment Guidelines Worldwide

Autoren: Lady Paola Aristizabal Arboleda, Genival Barbosa de Carvalho, Alan Roger Santos-Silva, Gisele Aparecida Fernandes, Jose Guilherme Vartanian, David I. Conway, Shama Virani, Paul Brennan, Luiz Paulo Kowalski, and Maria Paula Curado
Veröffentlicht in: Cancers, Ausgabe 3 Sep 2023, 2023, Seite(n) 1-13, ISSN 2072-6694
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers15174405

The COVID-19 pandemic has not changed stage at presentation nor treatment patterns of head and neck cancer: A retrospective cohort study

Autoren: Kelten Clements, Anna Cowell, Gillian White, William Flynn, David I. Conway, Catriona M. Douglas, Claire Paterson
Veröffentlicht in: Clinical Otolaryngology, Ausgabe 16 March 2023, 2023, Seite(n) 587-594, ISSN 1749-4486
Herausgeber: Wiley-Blackwell
DOI: 10.1111/coa.14048

Differential Expression of Potential Biomarkers of Oral Squamous Cell Carcinoma Development

Autoren: Paola Fernandes Pansini, Isabella Bittencourt do Valle, Thabata Coeli Dias Damasceno, Priscila Marinho de Abreu, Anna Clara Gregório Có, Rossana Verónica Mendoza López, Jeferson Lenzi, Ricardo Mai Rocha, Evandro Duccini Souza, Maria Paula Curado, Hisham Mehanna, Paul Nankivell, José Roberto Vasconcelos de Podestá, Sandra Ventorin von Zeidler.
Veröffentlicht in: Head and neck pathology, Ausgabe 11 April 2021, 2021, Seite(n) 1127–1136, ISSN 1936-0568
Herausgeber: Secaucus, NJ : Humana Press
DOI: 10.1007/s12105-021-01322-8

Reviewing the epidemiology of head and neck cancer: definitions, trends and risk factors

Autoren: Mark Gormley, Grant Creaney, Andrew Schache, Kate Ingarfield, David I Conway
Veröffentlicht in: British Dental Journal, Ausgabe 11 November 2022, 2022, ISSN 1476-5373
Herausgeber: Nature Portfolio
DOI: 10.1038/s41415-022-5166-x

Head and neck cancer in the UK: what was the stage before COVID-19? UK cancer registries analysis (2011-2018)

Autoren: Grant Creaney, Alex D. McMahon, Alastair J. Ross, Lesley A. Bhatti, Claire Paterson, and David I. Conway
Veröffentlicht in: British Dental Journal, Ausgabe 11 November 2022, 2022, Seite(n) 787-793, ISSN 1476-5373
Herausgeber: Nature Portfolio
DOI: 10.1038/s41415-022-5151-4

Germline determinants of humoral immune response to HPV-16 protect against oropharyngeal cancer

Autoren: Aida Ferreiro-Iglesias; James McKay; Nicole Brenner; Shama Virani; Corina Lesseur; Corina Lesseur; Valerie Gaborieau; Andy R Ness; Andy R Ness; Rayjean J. Hung; Geoffrey Liu; Brenda Diergaarde; Andrew F. Olshan; Neil Hayes; Mark C. Weissler; Lea Schroeder; Noemi Bender; Michael Pawlita; Steve Thomas; Miranda Pring; Tom Dudding; Beatriz Kanterewicz; Robert L. Ferris; Sera Thomas; Yonathan Brhane; V
Veröffentlicht in: Nature Communications, Ausgabe 12 October 2021, 2021, Seite(n) 1-11, ISSN 2041-1723
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41467-021-26151-9

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