Project description
A network for personalised medicine in oncology
The EUCANCan initiative funded by the EU will interconnect European and Canadian infrastructures for the analysis and management of genomic data in oncology. The generated platform will offer a uniform computing environment for the processing of cancer genomic and phenotypic data. The open and accessible data portal will follow the appropriate ethical and legal guidelines for secure data sharing. The long-term objective is to exploit this platform to fuel future research towards the identification of clinically relevant patterns of variation in the cancer genome, such as biomarkers predictive of therapeutic response.
Objective
We propose to create the EUropean-CANadian Cancer network (EUCANCan), a federated infrastructure whose mission is to enable Personalized Medicine in Oncology by promoting the generation and sharing of harmonized genomic and phenotypic data. EUCANCan builds on work performed by members of the consortium and related projects to align and interconnect existing European and Canadian infrastructures for the analysis and management of genomic oncology data. The EUCANCan network will be composed of reference nodes in Amsterdam, Barcelona, Berlin, Heidelberg, Paris and Toronto which have established strong research and clinical programs in the field of genomic oncology. These reference nodes will work together in an interoperable fashion to provide the genomic oncology community with a uniform computing environment for the processing, harmonization and secure sharing of cancer genome and phenome data in the context of clinical research, enabling the discovery of clinically-relevant patterns of variation in the cancer genome such as biomarkers predictive of therapeutic response. The infrastructure will also provide a proving ground for federated genome analysis systems that may one day be integrated into national and regional healthcare systems.
EUCANCan’s objectives are: (1) harmonise protocols for the identification and interpretation of germline and somatic variation profiles within cancer genomes; (2) generate strategies for the flow, management, storage and distribution of data within and across EUCANCan nodes; (3) define community standards for data elements, types and formats; (4) develop an open and accessible data portals for the searching and download of EUCANCan data; and (5) define an appropriate ethical and legal frame to ensure the secure sharing of protected individual genomic and phenotypic data across countries.
Fields of science
Programme(s)
Funding Scheme
RIA - Research and Innovation actionCoordinator
08034 Barcelona
Spain
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Participants (19)
69120 Heidelberg
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M5G 0 A3 TORONTO, ONTARIO
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75794 Paris
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1098 XH Amsterdam
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
08003 Barcelona
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69117 Heidelberg
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08036 Barcelona
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Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.
08036 Barcelona
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08908 L'HOSPITALET DEL LLOBREGAT
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08035 Barcelona
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69120 Heidelberg
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10117 Berlin
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75231 Paris
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H3A0G4 Montreal
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48940 Leioa
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Participation ended
69117 Heidelberg
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14057 BERLIN
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
70599 Stuttgart
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69117 Heidelberg
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