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EUCANCan: a federated network of aligned and interoperable infrastructures for the homogeneous analysis, management and sharing of genomic oncology data for Personalized Medicine.

Descrizione del progetto

Una rete per la medicina personalizzata in oncologia

L’iniziativa EUCANCan, finanziata dall’UE, connetterà tra loro le infrastrutture europee e canadesi per l’analisi e la gestione di dati genomici in oncologia. La piattaforma generata offrirà un ambiente informatico uniforme per l’elaborazione di dati genomici e fenotipici oncologici. Il portale di dati aperti e accessibili seguirà gli orientamenti etici e giuridici adeguati per la condivisione sicura dei dati. L’obiettivo a lungo termine è sfruttare la piattaforma per alimentare la ricerca futura verso l’identificazione di modelli clinicamente rilevanti di variazioni nel genoma del cancro, quali i biomarcatori predittivi di risposta terapeutica.

Obiettivo

We propose to create the EUropean-CANadian Cancer network (EUCANCan), a federated infrastructure whose mission is to enable Personalized Medicine in Oncology by promoting the generation and sharing of harmonized genomic and phenotypic data. EUCANCan builds on work performed by members of the consortium and related projects to align and interconnect existing European and Canadian infrastructures for the analysis and management of genomic oncology data. The EUCANCan network will be composed of reference nodes in Amsterdam, Barcelona, Berlin, Heidelberg, Paris and Toronto which have established strong research and clinical programs in the field of genomic oncology. These reference nodes will work together in an interoperable fashion to provide the genomic oncology community with a uniform computing environment for the processing, harmonization and secure sharing of cancer genome and phenome data in the context of clinical research, enabling the discovery of clinically-relevant patterns of variation in the cancer genome such as biomarkers predictive of therapeutic response. The infrastructure will also provide a proving ground for federated genome analysis systems that may one day be integrated into national and regional healthcare systems.

EUCANCan’s objectives are: (1) harmonise protocols for the identification and interpretation of germline and somatic variation profiles within cancer genomes; (2) generate strategies for the flow, management, storage and distribution of data within and across EUCANCan nodes; (3) define community standards for data elements, types and formats; (4) develop an open and accessible data portals for the searching and download of EUCANCan data; and (5) define an appropriate ethical and legal frame to ensure the secure sharing of protected individual genomic and phenotypic data across countries.

Invito a presentare proposte

H2020-SC1-BHC-2018-2020

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Bando secondario

H2020-SC1-2018-Single-Stage-RTD

Meccanismo di finanziamento

RIA - Research and Innovation action

Coordinatore

BARCELONA SUPERCOMPUTING CENTER CENTRO NACIONAL DE SUPERCOMPUTACION
Contribution nette de l'UE
€ 774 750,00
Indirizzo
CALLE JORDI GIRONA 31
08034 Barcelona
Spagna

Mostra sulla mappa

Regione
Este Cataluña Barcelona
Tipo di attività
Research Organisations
Collegamenti
Costo totale
€ 774 750,00

Partecipanti (19)