Skip to main content

Personalized Recommendations for Neurodegenerative Disease

Ziel

The annual worldwide cost of Alzheimer’s dementia was 777.81 billion Euro in 2015. This number will rise to 7.41 trillion Euro in 2050. Early diagnosis would save up to $7.9 trillion in medical and care costs by 2050 in the US alone. However, the emergent pathology is highly variable across people, necehighly variable across people, necessitating individualized diagnostics and interventions. The VirtualBrainCloud addresses this by bridging the gap between computational neuroscience and subcellular systems biology, integrating both research streams into a unifying computational model that supports personalized diagnostics and treatments in NDD. TheVirtualBrainCloud not only integrates existing software tools, it also merges the efforts of two big EU initiatives, namely The Virtual Brain large scale simulation platform of the EU Flagship Human Brain Project and IMI-EPAD initiative (European prevention of Alzheimer’s dementia consortium). VirtualBrainCloud will develop and validate a decision support system that provides access to high quality multi-disciplinary data for clinical practice. The result will be a cloud-based brain simulation platform to support personalized diagnostics and treatments in NDD. The EU PRACE (Partnership for Advanced Computing in Europe) initiative, will provide the required computing infrastructure. The VirtualBrainCloud will develop robust solutions for legal and ethical matters by interacting with EU projects such as European Open Science Cloud (EOSC), ‘cloud4health’, Alzheimer’s Europe patient organizations and ELIXIR, an organization that manages and safeguards EU research data. Our software developers have already produced highly successful brain simulation and clinical decision support tools. The resulting software will be a cloud based computational modeling system that is tailored to the individual, and bridges multiple scales to identify key mechanisms that predict NDD progression and serves as Precision Decision Support System.

Aufforderung zur Vorschlagseinreichung

H2020-SC1-DTH-2018-1
Andere Projekte für diesen Aufruf anzeigen

Koordinator

CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Adresse
Chariteplatz 1
10117 Berlin
Deutschland
Aktivitätstyp
Higher or Secondary Education Establishments
EU-Beitrag
€ 1 985 750

Beteiligte (16)

UNIVERSITE D'AIX MARSEILLE
Frankreich
EU-Beitrag
€ 1 107 093,10
Adresse
Boulevard Charles Livon 58
13284 Marseille
Aktivitätstyp
Higher or Secondary Education Establishments
FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
Deutschland
EU-Beitrag
€ 1 868 750
Adresse
Hansastrasse 27C
80686 Munchen
Aktivitätstyp
Research Organisations
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
EU-Beitrag
€ 462 430
Adresse
Wellington Square University Offices
OX1 2JD Oxford
Aktivitätstyp
Higher or Secondary Education Establishments
FORSCHUNGSZENTRUM JULICH GMBH
Deutschland
EU-Beitrag
€ 3 736 728,74
Adresse
Wilhelm Johnen Strasse
52428 Julich
Aktivitätstyp
Research Organisations
INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE
Frankreich
EU-Beitrag
€ 1 188 750
Adresse
Boulevard De L'hopital 47
75013 Paris
Aktivitätstyp
Research Organisations
INSTITUT NATIONAL DE RECHERCHE EN INFORMATIQUE ET AUTOMATIQUE
Frankreich
EU-Beitrag
€ 324 435
Adresse
Domaine De Voluceau Rocquencourt
78153 Le Chesnay Cedex
Aktivitätstyp
Research Organisations
FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA
Spanien
EU-Beitrag
€ 686 937,50
Adresse
Carrer Baldiri Reixac Planta 2A 10-12
08028 Barcelona
Aktivitätstyp
Research Organisations
HELSINGIN YLIOPISTO
Finnland
EU-Beitrag
€ 840 280
Adresse
Yliopistonkatu 3
00014 Helsingin Yliopisto
Aktivitätstyp
Higher or Secondary Education Establishments
UNIVERSITA DEGLI STUDI DI GENOVA
Italien
EU-Beitrag
€ 425 091,25
Adresse
Via Balbi 5
16126 Genova
Aktivitätstyp
Higher or Secondary Education Establishments
UNIVERSIDAD COMPLUTENSE DE MADRID
Spanien
EU-Beitrag
€ 396 250
Adresse
Avenida De Seneca 2
28040 Madrid
Aktivitätstyp
Higher or Secondary Education Establishments
CODEBOX GMBH
Deutschland
EU-Beitrag
€ 148 750
Adresse
Hugo Eckener Strasse 7
70184 Stuttgart
Aktivitätstyp
Private for-profit entities (excluding Higher or Secondary Education Establishments)
CODEMART SRL
Rumänien
EU-Beitrag
€ 422 750
Adresse
Str Petofi Sandor 13 Ap 4
400610 Cluj-napoca
Aktivitätstyp
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EODYNE SYSTEMS SL
Spanien
EU-Beitrag
€ 407 500
Adresse
Cl Venezuela 35 First Floor
08019 Barcelona
Aktivitätstyp
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITAT WIEN
Österreich
EU-Beitrag
€ 462 097,50
Adresse
Universitatsring 1
1010 Wien
Aktivitätstyp
Higher or Secondary Education Establishments
TP21 GMBH
Deutschland
EU-Beitrag
€ 376 250
Adresse
Luisenstrasse 14
10117 Berlin
Aktivitätstyp
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ALZHEIMER EUROPE
Luxemburg
EU-Beitrag
€ 176 500
Adresse
Rue Dicks 14
1417 Luxembourg
Aktivitätstyp
Other