Silk-based ocular implants: treating eye conditions at the interface of photonics and biology

Informazioni relative al progetto

SILK-EYE

ID dell’accordo di sovvenzione: 833106

DOI

10.3030/833106

Data della firma CE 29 Maggio 2019

Data di avvio 1 Gennaio 2020

Data di completamento 31 Dicembre 2025

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 2 499 610,00

Contributo UE

€ 2 499 610,00

Coordinato da

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Spain

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Conference proceedings (11)

Improving corneal stroma repair with Silk Fibroin-derived membranes

Autori: Patricia Gallego-Muñoz; Eduardo Ontoria; Mar Fernandez Gutierrez; Rocio Gutierrez-Contreras; Paula Olaya; Susana Marcos; M. Carmen Martínez García
Pubblicato in: Investigative Ophthalmology & Visual Science, Numero Volume 63, Numero 7, 2022
Editore: ARVO JOURNAL

Growth-factor controlled release in silk fibroin-based corneal bandages

Autori: Mar Fernandez-Gutierrez; Rocio Gutierrez Contreras; Paula Olalla; Andres De la Hoz; Eduardo Ontoria; Patricia Gallego-Muñoz; Maria del Carmen Martinez; Susana Marcos
Pubblicato in: Investigative Ophthalmology & Visual Science, 2023
Editore: ARVO

Biomechanical effects of Scleral crosslinking using Rose Bengal/Green-light and Rivoflavin/UVA

Autori: Lupe Villegas; James Germann; Susana Marcos
Pubblicato in: Investigative Ophthalmology & Visual Science, Numero Volume 62, Numero 8, 2021
Editore: ARVO Journals

Collagen Organization in the Posterior Rabbit Sclera Post Cross-Linking

Autori: James Germann; Lupe Villegas; Eduardo Martinez-Enriquez; Luis Revuelta; Blanca Cómitre; Daniel Sanderson; Vicente Llorente; Manuel Desco; María Victoria Gómez-Gaviro; Susana Marcos
Pubblicato in: Investigative Ophthalmology & Visual Science, Numero Volume 62, Numero 8, 2021
Editore: ARVO Journals

Silk fibroin hydrogel corneal inlays: material and modeling

Autori: Rocio Gutierrez-Contreras; Andres De La Hoz; Mar Fernandez-Gutierrez; Paula Olalla; Susana Marcos
Pubblicato in: Investigative Ophthalmology & Visual Science, 2024
Editore: ARVO

Nonlinear susceptibility of collagen fibers in ocular tissue with a new IR laser source

Autori: James Andrew Germann; Gaia Sardiello; Sara Otero Barros; Susana Marcos
Pubblicato in: Investigative Ophthalmology & Visual Science, Numero Volume 63, Numero 7, 2022
Editore: ARVO Journals

Corneal biomechanical parameters in healthy and early-stage keratoconus eyes from cross-meridian air-puff deformation OCT

Autori: Judith Sophie Birkenfeld; Alejandra Varea; Andrea Curatolo; Ashkan Eliasy; Ana Maria Gonzalez; Eduardo Martinez-Enriquez; Ahmed Abass; Bernardo Lopes; Ahmed Elsheikh; Jesus Merayo-Lloves; Susana Marcos
Pubblicato in: Investigative Ophthalmology & Visual Science, Numero Volume 63, Numero 7, 2022
Editore: ARVO Journals

Estimation of the full shape of the crystalline lens from optical coherence tomography images using Eigenlenses

Autori: Eduardo Martinez-Enriquez; Andrea Curatolo; Judith Sophie Birkenfeld; Ana Maria Gonzalez; Alberto de Castro; Ashik Mohamed; Marco Ruggeri; Fabrice Manns; Susana Marcos
Pubblicato in: Investigative Ophthalmology & Visual Science, Numero Volume 63, Numero 7, 2022
Editore: ARVO Journals

Silk fibroin films for corneal healing: towards optimal photobonding parameters

Autori: Rocio Gutierrez-Contreras et al.
Pubblicato in: 2022
Editore: Poster contribution at the Iberic Meeting of Optics Students 2022

Human crystalline lens refractive index distribution: age-related changes consistent with optical behavior

Autori: Alberto de Castro; Eduardo Martinez-Enriquez; Bianca Maceo Heilman; Marco Ruggeri; Ramya Natarajan; Ashik Mohamed; Fabrice Manns; Susana Marcos
Pubblicato in: Investigative Ophthalmology & Visual Science, 2023
Editore: ARVO

Demonstration of sutureless fixation of silk fibroin based corneal bandages ex vivo and in vivo

Autori: Rocio Gutierrez-Contreras; Patricia Gallego-Muñoz; Andres De la Hoz; Mar Fernandez-Gutierrez; Paula Olalla; Eduardo Ontoria; Maria del Carmen Martinez; Susana Marcos
Pubblicato in: Investigative Ophthalmology & Visual Science, 2023
Editore: ARVO

Peer reviewed articles (18)

Accommodation through simulated multifocal optics

Autori: Shrilekha Vedhakrishnan, Alberto de Castro, Maria Vinas, Sara Aissati, Susana Marcos
Pubblicato in: Biomedical Optics Express, Numero 13, 2024, Pagina/e 6695, ISSN 2156-7085
Editore: The Optical Society
DOI: 10.1364/boe.473595

Matching convolved images to optically blurred images on the retina

Autori: Sara Aissati, Clara Benedi-Garcia, Maria Vinas, Alberto de Castro, Susana Marcos
Pubblicato in: Journal of Vision, Numero 22, 2022, Pagina/e 12, ISSN 1534-7362
Editore: Association for Research in Vision and Ophthalmology
DOI: 10.1167/jov.22.2.12

Estimation of the full shape of the crystalline lens from OCT: validation using stretched donor lenses

Autori: Eduardo Martinez-Enriquez, Bianca Maceo Heilman, Alberto de Castro, Ashik Mohamed, Marco Ruggeri, Fernando Zvietcovich, Fabrice Manns, Susana Marcos
Pubblicato in: Biomedical Optics Express, Numero Vol. 14, Numero 2, 2023, ISSN 2156-7085
Editore: The Optical Society
DOI: 10.1364/opticaopen.22672966.v1

Simulating Outcomes of Cataract Surgery: Important Advances in Ophthalmology.

Autori: Susana Marcos; Eduardo Martinez-Enriquez; Maria Vinas; Alberto de Castro; Carlos Dorronsoro; Seung Pil Bang; Geunyoung Yoon; Pablo Artal
Pubblicato in: Annual Review of Biomedical Engineering, Numero 5, 2021, ISSN 1523-9829
Editore: Annual Reviews, Inc.
DOI: 10.1146/annurev-bioeng-082420-035827

Estimation of Crystalline Lens Material Properties From Patient Accommodation Data and Finite Element Models

Autori: Andres de la Hoz, Eduardo Martinez-Enriquez, Susana Marcos
Pubblicato in: Investigative Opthalmology & Visual Science, Numero 64, 2023, Pagina/e 31, ISSN 1552-5783
Editore: ARVO
DOI: 10.1167/iovs.64.11.31

Visual simulations of presbyopic corrections through cataract opacification

Autori: Xoana Barcala, Amal Zaytouny, Daniela Rego-Lorca, Julia Sanchez-Quiros, Ruben Sanchez-Jean, Jose Maria Martinez-de-la-Casa, Carlos Dorronsoro, Susana Marcos
Pubblicato in: Journal of Cataract and Refractive Surgery, Numero 49, 2023, Pagina/e 34-43, ISSN 0886-3350
Editore: Elsevier BV
DOI: 10.1097/j.jcrs.0000000000001040

Poster Session: Experimental assessment of scleral anisotropy using multi-meridian air-coupled ultrasonic optical coherence elastography

Autori: Lupe Villegas, Fernando Zvietcovich, Alejandra Varea, Andrea Curatolo, Judith S. Birkenfeld, Susana Marcos
Pubblicato in: Journal of Vision, Numero 23, 2023, Pagina/e 72, ISSN 1534-7362
Editore: Association for Research in Vision and Ophthalmology
DOI: 10.1167/jov.23.11.72

Estimation of scleral mechanical properties from air-puff optical coherence tomography

Autori: David Bronte-Ciriza; Judith Birkenfeld; Andres De la Hoz; Andrea Curatolo; James A. Germann; Lupe Villegas; Alejandra Varea; Eduardo Martinez-Enriquez; Susana Marcos
Pubblicato in: Biomed Optics Express, Numero 2, 2021, ISSN 2156-7085
Editore: The Optical Society
DOI: 10.1364/boe.437981

Comparative Analysis of Silk Fibroin Membranes across Cross-Linking Methods: Processing and Characterization

Autori: Rocio Gutierrez-Contreras, Mar Fernandez-Gutierrez, Paula Olalla-Perez, Andres De La Hoz, Susana Marcos
Pubblicato in: ACS Omega, Numero 9, 2024, Pagina/e 38452-38461, ISSN 2470-1343
Editore: ACS Publications
DOI: 10.1021/acsomega.4c02204

Visual performance with multifocal lenses in young adults and presbyopes

Autori: Shrilekha Vedhakrishnan,Maria Vinas,Clara Benedi-Garcia,Pilar Casado,Susana Marcos
Pubblicato in: PLOS ONE, 2022, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0263659

A simple computational model for scleral stiffness assessments via air-puff deformation OCT

Autori: Andres De La Hoz, Lupe Villegas, Susana Marcos, Judith S. Birkenfeld
Pubblicato in: Frontiers in Bioengineering and Biotechnology, Numero 12, 2024, ISSN 2296-4185
Editore: Frontiers
DOI: 10.3389/fbioe.2024.1426060

Isolated human crystalline lens three-dimensional shape: A comparison between Indian and European populations

Autori: Ashik Mohamed, Sushma Nandyala, Eduardo Martinez-Enriquez, Bianca Maceo Heilman, Robert C. Augusteyn, Alberto de Castro, Marco Ruggeri, Jean-Marie A. Parel, Susana Marcos, Fabrice Manns
Pubblicato in: Experimental Eye Research, Numero 205, 2021, Pagina/e 108481, ISSN 0014-4835
Editore: Academic Press
DOI: 10.1016/j.exer.2021.108481

Effects of Different Scleral Photo-Crosslinking Modalities on Scleral Stiffness and Hydration

Autori: Lupe Villegas, James A. Germann, Susana Marcos
Pubblicato in: Investigative Ophthalmology & Visual Science, Numero 65, 2024, Pagina/e 8, ISSN 1552-5783
Editore: ARVO
DOI: 10.1167/iovs.65.8.8

Co-axial acoustic-based optical coherence vibrometry probe for the quantification of resonance frequency modes in ocular tissue

Autori: Ryan McAuley, A. Nolan, A. Curatolo, S. Alexandrov, F. Zvietcovich, A. Varea Bejar, S. Marcos, M. Leahy, J. S. Birkenfeld
Pubblicato in: Scientific Reports, Numero 12, 2022, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-022-21978-8

Functional integration of eye tissues and refractive eye development: Mechanisms and pathways

Autori: Jody A. Summers; Frank Schaeffel; Susana Marcos; Hao Wu; Andrei V. Tkatchenko
Pubblicato in: Experimental Eye Research, Numero 2, 2021, ISSN 0014-4835
Editore: Academic Press
DOI: 10.1016/j.exer.2021.108693

Vision with spatial light modulator simulating multifocal contact lenses in an adaptive optics system.

Autori: Shrilekha Vedhakrishnan; Maria Vinas; Sara Aissati; Susana Marcos
Pubblicato in: Biomedical Optical Express, Numero 3, 2021, ISSN 2156-7085
Editore: The Optical Society
DOI: 10.1364/boe.419680

Revealing regional variations in scleral shear modulus in a rabbit eye model using multi-directional ultrasound optical coherence elastography

Autori: Lupe Villegas, Fernando Zvietcovich, Susana Marcos, Judith S. Birkenfeld
Pubblicato in: Scientific Reports, Numero 14, 2024, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-024-71343-0

Multifocal contact lens vision simulated with a clinical binocular simulator

Autori: Xoana Barcala, Maria Vinas, Sofia Ruiz, Fernando Hidalgo, Derek Nankivile, Tom Karkkainen, Enrique Gambra, Carlos Dorronsoro, Susana Marcos
Pubblicato in: Contact Lens and Anterior Eye, 2022, ISSN 1367-0484
Editore: Elsevier BV
DOI: 10.1016/j.clae.2022.101716