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New Horizons in C–H Activation: the ‘Real-World Molecules’ Challenge

Project description

Catalysts with 'kid gloves' gently replace hydrogen with delicate bioactive entities

Pharmaceuticals improve life expectancy, quality of life and health outcomes for countless conditions and diseases, yet their development is struggling to realise its full potential. This is in large part due to the characteristics of the ubiquitous, essential yet hard-to-break carbon–hydrogen (C–H) bond. Pulling hydrogens off bioactive molecules and replacing them with functional entities requires harsh reaction conditions unsuitable for the "survival" of many of these functional groups. The EU-funded RuCat project has the key to unlock the door to functionalisations not previously possible thanks to its exceptional new catalysts for C–H activation.

Host institution

THE UNIVERSITY OF MANCHESTER
Net EU contribution
€ 2 498 959,00
Address
Oxford Road
M13 9PL Manchester
United Kingdom

See on map

Region
North West (England) Greater Manchester Manchester
Activity type
Higher or Secondary Education Establishments
Other funding
€ 2 498 959,00

Beneficiaries (1)

THE UNIVERSITY OF MANCHESTER
United Kingdom
Net EU contribution
€ 2 498 959,00
Address
Oxford Road
M13 9PL Manchester

See on map

Region
North West (England) Greater Manchester Manchester
Activity type
Higher or Secondary Education Establishments
Other funding
€ 2 498 959,00