New Horizons in C–H Activation: the ‘Real-World Molecules’ Challenge

Project description

Catalysts with 'kid gloves' gently replace hydrogen with delicate bioactive entities

Pharmaceuticals improve life expectancy, quality of life and health outcomes for countless conditions and diseases, yet their development is struggling to realise its full potential. This is in large part due to the characteristics of the ubiquitous, essential yet hard-to-break carbon–hydrogen (C–H) bond. Pulling hydrogens off bioactive molecules and replacing them with functional entities requires harsh reaction conditions unsuitable for the "survival" of many of these functional groups. The EU-funded RuCat project has the key to unlock the door to functionalisations not previously possible thanks to its exceptional new catalysts for C–H activation.

Fields of science

• medical and health sciences › basic medicine › pharmacology and pharmacy › drug discovery
• natural sciences › chemical sciences › inorganic chemistry › transition metals
• natural sciences › chemical sciences › catalysis

Programme(s)

• H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme

Topic(s)

• ERC-2018-ADG - ERC Advanced Grant

Call for proposal

ERC-2018-ADG

See other projects for this call

Funding Scheme

ERC-ADG - Advanced Grant

Host institution

THE UNIVERSITY OF MANCHESTER

Net EU contribution

€ 2 498 959,00

Address

Oxford Road
M13 9PL Manchester
United Kingdom

Region

North West (England) › Greater Manchester › Manchester

Activity type

Higher or Secondary Education Establishments

Links

Other funding

€ 2 498 959,00

Beneficiaries (1)

THE UNIVERSITY OF MANCHESTER

United Kingdom

Net EU contribution

€ 2 498 959,00

Address

Oxford Road
M13 9PL Manchester

Region

North West (England) › Greater Manchester › Manchester

Activity type

Higher or Secondary Education Establishments

Links

Other funding

€ 2 498 959,00