Research sheds light on how astrocytes govern neural connections
Funded by the Marie Skłodowska-Curie Actions programme, the ASTRALIS project seeks to increase understanding of how intracellular signalling complexity is generated in the brain. The project will focus on brain cells called astrocytes that are highly interconnected but electrically silent and signal through G protein-coupled receptors and second messengers in response to norepinephrine. These brain cells will be used as models to study whether intracellular signalling in vivo is governed extrinsically or intrinsically. Elucidating the largely disregarded contribution of astrocytes in noradrenergic signalling at the cellular and network level should further understanding of the pathophysiology of related disorders and help conceive better therapeutic strategies.
Fields of science
Funding SchemeMSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
94607 Oakland Ca
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