Project description
Towards bespoke tissue scaffolds
Much like construction scaffolds help in building an office building, tissue scaffolds help cells form functional tissues for treatment of disease or injury. Designed to encourage cell growth and tissue formation, tissue scaffolds are microscopic, often nanostructured, and must be biocompatible. With support of the Marie Skłodowska-Curie programme, BioSMaLL is integrating a novel 3D printing method called solution mask liquid lithography (SMaLL) with functional biopolymers and tissue engineering. SMaLL exploits photo-active molecules to control polymerisation and create novel 3D structures with chemically and mechanically distinct domains. The result will be improved tailor-made and bioinspired tissue implants for a variety of biomedical applications.
Objective
Three-dimensional (3D) printing in biomedical science has recently advanced the development of tailor-made implants. Designing structural and functional 3D constructs mimetic of both tissues and organs offers a genuine route to personalised implants, improving the patients' quality of life and reducing healthcare costs. While engineers have significantly progressed 3D printing methods, the barriers to progress include the limited variety of printable materials as well as the need for alternative low-cost printing technologies. BioSMaLL aims to address this through combining Solution Mask Liquid Lithography (SMaLL), a recent technology developed at the University of California Santa Barbara (UCSB), with the expertise of the applicant and the Royal College of Surgeons in Ireland (RCSI) in functional biopolymers and tissue engineering to develop bio-active scaffolds. The objectives of this global fellowship will be achieved by adaptation of BioSMaLL for newly designed biopolymers during the outgoing phase at UCSB . In a transfer of knowledge, BioSMaLL will then be established at RCSI and bespoke biocompatible scaffolds produced and validated during the incoming phase. The innovative approach will be facilitated by an interdisciplinary methodology at the interface of polymer chemistry, (bio)materials science, 3D printing and tissue engineering in two world-renowned groups. The career goal of the fellow to embark on a career in emerging biomedical technologies in a start-up company will be facilitated by a dedicated training programme across scientific methods as well as complementary training at UCSB and RCSI covering leadership, project management and commercialisation in addition to meetings with laboratory and management staff of the start-up company SurgaColl. The partners have a proven track record in training future leaders in materials science and healthcare aiming to make a difference and establish new technologies and innovative processes in Europe and beyond.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences medical biotechnology tissue engineering
- natural sciences chemical sciences polymer sciences
- engineering and technology mechanical engineering manufacturing engineering additive manufacturing
- medical and health sciences medical biotechnology implants
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2018
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
2 DUBLIN
Ireland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.