Description du projet DEENESFRITPL Vers des échafaudages tissés sur mesure Tout comme les échafaudages de construction aident à construire un immeuble de bureaux, les échafaudages de tissu aident les cellules à former des tissus fonctionnels pour le traitement de maladies ou de blessures. Conçus pour encourager la croissance cellulaire et la formation de tissus, les échafaudages tissulaires sont microscopiques, souvent nanostructurés, et doivent être biocompatibles. Soutenu par le programme Marie Skłodowska-Curie, le projet BioSMaLL intègre une nouvelle méthode d’impression 3D appelée lithographie liquide en solution avec masque (SMaLL) avec des biopolymères fonctionnels et l’ingénierie tissulaire. SMaLL exploite des molécules photo-actives pour contrôler la polymérisation et créer de nouvelles structures 3D avec des domaines chimiquement et mécaniquement distincts. Le résultat sera des implants tissulaires sur mesure et bioinspirés améliorés pour une variété d’applications biomédicales. Afficher les objectifs du projet Masquer les objectifs du projet Objectif Three-dimensional (3D) printing in biomedical science has recently advanced the development of tailor-made implants. Designing structural and functional 3D constructs mimetic of both tissues and organs offers a genuine route to personalised implants, improving the patients' quality of life and reducing healthcare costs. While engineers have significantly progressed 3D printing methods, the barriers to progress include the limited variety of printable materials as well as the need for alternative low-cost printing technologies. BioSMaLL aims to address this through combining Solution Mask Liquid Lithography (SMaLL), a recent technology developed at the University of California Santa Barbara (UCSB), with the expertise of the applicant and the Royal College of Surgeons in Ireland (RCSI) in functional biopolymers and tissue engineering to develop bio-active scaffolds. The objectives of this global fellowship will be achieved by adaptation of BioSMaLL for newly designed biopolymers during the outgoing phase at UCSB . In a transfer of knowledge, BioSMaLL will then be established at RCSI and bespoke biocompatible scaffolds produced and validated during the incoming phase. The innovative approach will be facilitated by an interdisciplinary methodology at the interface of polymer chemistry, (bio)materials science, 3D printing and tissue engineering in two world-renowned groups. The career goal of the fellow to embark on a career in emerging biomedical technologies in a start-up company will be facilitated by a dedicated training programme across scientific methods as well as complementary training at UCSB and RCSI covering leadership, project management and commercialisation in addition to meetings with laboratory and management staff of the start-up company SurgaColl. The partners have a proven track record in training future leaders in materials science and healthcare aiming to make a difference and establish new technologies and innovative processes in Europe and beyond. Champ scientifique medical and health sciencesmedical biotechnologytissue engineeringnatural scienceschemical sciencespolymer sciencesengineering and technologymechanical engineeringmanufacturing engineeringadditive manufacturingmedical and health sciencesmedical biotechnologyimplants Mots‑clés polymer synthesis polypeptides 3D printing UV resin biocompatibility tissue engineering Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Thème(s) MSCA-IF-2018 - Individual Fellowships Appel à propositions H2020-MSCA-IF-2018 Voir d’autres projets de cet appel Régime de financement MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF) Coordinateur ROYAL COLLEGE OF SURGEONS IN IRELAND Contribution nette de l'UE € 257 561,28 Adresse ST STEPHEN'S GREEN 123 2 Dublin Irlande Voir sur la carte Région Ireland Northern and Western Border Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 257 561,28 Partenaires (1) Trier par ordre alphabétique Trier par contribution nette de l'UE Tout développer Tout réduire Partenaire Les organisations partenaires contribuent à la mise en œuvre de l’action, mais ne signent pas la convention de subvention. THE REGENTS OF THE UNIVERSITY OF CALIFORNIA États-Unis Contribution nette de l'UE € 0,00 Adresse FRANKLIN STREET 1111 12 FLOOR 94607 OAKLAND CA Voir sur la carte Type d’activité Higher or Secondary Education Establishments Liens Contacter l’organisation Opens in new window Site web Opens in new window Participation aux programmes de R&I de l'UE Opens in new window Réseau de collaboration HORIZON Opens in new window Coût total € 165 265,92
