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Determination of bacterial vesicles interactions in the most abundant marine cyanobacteria and its potential applications

Description du projet

Explorer le rôle crucial des microbes marins microscopiques

Invisibles à l’œil nu, les microbes marins sont essentiels, non seulement parce qu’ils assurent une part importante de la production océanique, mais aussi parce qu’ils ont une influence sur le climat. Le projet VESYNECH, financé par l’UE, étudiera le rôle des vésicules microbiennes marines des picocyanobactéries du genre Synechococcus, qui dominent la plupart des assemblages de phytoplancton dans les océans et interagissent à différentes échelles spatiales et temporelles. Il s’agira, plus précisément, de caractériser les vésicules microbiennes de différentes souches de la cyanobactérie Synechococcus. Il identifiera les fonctions potentielles des vésicules des cyanobactéries marines et leur rôle en tant que vecteurs dans le transfert horizontal de gènes. Les résultats mettront en lumière le potentiel bioactif éventuel des gènes et des enzymes.

Objectif

In recent years, there has been an increasing recognition of the importance of marine microbes, coupled with the discovery of a vast microbial diversity in the oceans. Remarkable examples of this importance are the cyanobacteria, which are responsible for more than 50% of the oxygen production on Earth. Marine picocyanobacteria (i.e. Synechococcus) dominate most phytoplankton assemblages in oceans interacting over different spatial and temporal scales. Interactions mediated by uptake of proteins, lipids or metabolites, quorum signaling, viruses or by the secretion of membrane vesicles, have a large ecological impact on community structure. VESYNECH is an ambitious project with the aim of gaining a comprehensive understanding of the role of marine microbial vesicles of Synechococcus and its implications in the microbial diversity in the ocean. The abundant and ecological importance of these marine microorganisms as contributors of global primary production in the ocean reinforces the relevance of this project. To fully understand how these vesicles are implicated in these interactions, I will characterize the microbial vesicles of different strains of the cyanobacterium Synechococcus. Furthermore, I will determine the potential functions of vesicles from marine cyanobacteria and its role in the horizontal gene transfer. Finally, I will explore the content of these vesicles to unveil possible bioactive potential of genes and enzymes. This project will be carried out at the García-Fernández lab at the University of Córdoba, Spain with the expertise in physiological studies in marine cyanobacteria, providing me with an excellent training through research, acquiring additional research skills and gaining experience in the leadership and management of projects.

Coordinateur

UNIVERSIDAD DE CORDOBA
Contribution nette de l'UE
€ 160 932,48
Adresse
AVENIDA DE MEDINA AZAHARA 5
14005 Cordoba
Espagne

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Région
Sur Andalucía Córdoba
Type d’activité
Higher or Secondary Education Establishments
Liens
Coût total
€ 160 932,48