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Determination of bacterial vesicles interactions in the most abundant marine cyanobacteria and its potential applications

Projektbeschreibung

Die große Rolle winziger Meeresmikroben

Sie mögen für das bloße Auge nicht sichtbar sein, doch Meeresmikroben sind als Großerzeuger in den Ozeanen von immenser Bedeutung. Außerdem beeinflussen sie das Klima. Das EU-finanzierte Projekt VESYNECH will nun die Rolle mariner mikrobieller Vesikel von Picocyanobakterien wie dem Synechococcus erforschen, die bei den meisten Ansammlungen von Phytoplankton in den Ozeanen vorherrschen und räumlich wie zeitlich in völlig verschiedenen Maßstäben miteinander interagieren. Besonders die mikrobiellen Vesikel verschiedener Stämme des Cyanobakteriums Synechococcus sollen charakterisiert werden. Außerdem werden die potenziellen Funktionen der Vesikel mariner Cyanobakterien sowie ihre Rolle im horizontalen Gentransfer herausgearbeitet. Anhand dieser Erkenntnisse sollte das mögliche bioaktive Potenzial von Genen und Enzymen deutlich werden.

Ziel

In recent years, there has been an increasing recognition of the importance of marine microbes, coupled with the discovery of a vast microbial diversity in the oceans. Remarkable examples of this importance are the cyanobacteria, which are responsible for more than 50% of the oxygen production on Earth. Marine picocyanobacteria (i.e. Synechococcus) dominate most phytoplankton assemblages in oceans interacting over different spatial and temporal scales. Interactions mediated by uptake of proteins, lipids or metabolites, quorum signaling, viruses or by the secretion of membrane vesicles, have a large ecological impact on community structure. VESYNECH is an ambitious project with the aim of gaining a comprehensive understanding of the role of marine microbial vesicles of Synechococcus and its implications in the microbial diversity in the ocean. The abundant and ecological importance of these marine microorganisms as contributors of global primary production in the ocean reinforces the relevance of this project. To fully understand how these vesicles are implicated in these interactions, I will characterize the microbial vesicles of different strains of the cyanobacterium Synechococcus. Furthermore, I will determine the potential functions of vesicles from marine cyanobacteria and its role in the horizontal gene transfer. Finally, I will explore the content of these vesicles to unveil possible bioactive potential of genes and enzymes. This project will be carried out at the García-Fernández lab at the University of Córdoba, Spain with the expertise in physiological studies in marine cyanobacteria, providing me with an excellent training through research, acquiring additional research skills and gaining experience in the leadership and management of projects.

Koordinator

UNIVERSIDAD DE CORDOBA
Netto-EU-Beitrag
€ 160 932,48
Adresse
AVENIDA DE MEDINA AZAHARA 5
14005 Cordoba
Spanien

Auf der Karte ansehen

Region
Sur Andalucía Córdoba
Aktivitätstyp
Higher or Secondary Education Establishments
Links
Gesamtkosten
€ 160 932,48