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Determination of bacterial vesicles interactions in the most abundant marine cyanobacteria and its potential applications

Descrizione del progetto

Esplorare il grande ruolo dei piccoli microbi marini

Invisibili a occhio nudo, i microbi marini sono molto importanti come produttori significativi negli oceani e influenzano anche il clima. Il progetto VESYNECH, finanziato dall’UE, studierà il ruolo delle vescicole microbiche marine dei picocianobatteri marini come il Synechococcus, che dominano la maggior parte dei gruppi di fitoplancton negli oceani interagendo su diverse scale spaziali e temporali. In particolare, il progetto caratterizzerà le vescicole microbiche di diversi ceppi del cianobatterio Synechococcus e individuerà le potenziali funzioni delle vescicole dei cianobatteri marini e il loro ruolo nel trasferimento genico orizzontale. I risultati faranno luce sul possibile potenziale bioattivo di geni ed enzimi.

Obiettivo

In recent years, there has been an increasing recognition of the importance of marine microbes, coupled with the discovery of a vast microbial diversity in the oceans. Remarkable examples of this importance are the cyanobacteria, which are responsible for more than 50% of the oxygen production on Earth. Marine picocyanobacteria (i.e. Synechococcus) dominate most phytoplankton assemblages in oceans interacting over different spatial and temporal scales. Interactions mediated by uptake of proteins, lipids or metabolites, quorum signaling, viruses or by the secretion of membrane vesicles, have a large ecological impact on community structure. VESYNECH is an ambitious project with the aim of gaining a comprehensive understanding of the role of marine microbial vesicles of Synechococcus and its implications in the microbial diversity in the ocean. The abundant and ecological importance of these marine microorganisms as contributors of global primary production in the ocean reinforces the relevance of this project. To fully understand how these vesicles are implicated in these interactions, I will characterize the microbial vesicles of different strains of the cyanobacterium Synechococcus. Furthermore, I will determine the potential functions of vesicles from marine cyanobacteria and its role in the horizontal gene transfer. Finally, I will explore the content of these vesicles to unveil possible bioactive potential of genes and enzymes. This project will be carried out at the García-Fernández lab at the University of Córdoba, Spain with the expertise in physiological studies in marine cyanobacteria, providing me with an excellent training through research, acquiring additional research skills and gaining experience in the leadership and management of projects.

Coordinatore

UNIVERSIDAD DE CORDOBA
Contribution nette de l'UE
€ 160 932,48
Indirizzo
AVENIDA DE MEDINA AZAHARA 5
14005 Cordoba
Spagna

Mostra sulla mappa

Regione
Sur Andalucía Córdoba
Tipo di attività
Higher or Secondary Education Establishments
Collegamenti
Costo totale
€ 160 932,48