New insights into human genetic variation
Many human traits are highly polygenic and are governed by multiple genetic loci. The adaptation of such complex phenotypes takes place through small changes in allele frequencies at these loci. The EU-funded PATTERNS project proposes to study how polygenic adaptation may act on complex phenotypes through gene expression regulation, an aspect that has largely been overlooked. Scientists will combine network biology and population genetics methods to study the impact of polygenic adaptation on gene expression regulation. Results will provide a better understanding of how polygenic adaptation drives genetic diversity in humans and the extent to which it contributes to diseases.
Fields of science
Call for proposalSee other projects for this call
Funding SchemeMSCA-IF-EF-ST - Standard EF
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