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GPCR-based biosensor for synthetic biology applications

Project description

Novel biosensors for the microbial production factories

Microbial cell factories represent an economical and sustainable alternative for the production of pharmaceuticals and industrial chemicals. The lack of high-throughput methods for monitoring product accumulation is one of the obstacles in this process. The EU-funded GPCR-Sensor project aims to use G-protein coupled receptors (GPCRs), the eukaryotes' environmental sensors, to create a versatile in vivo biosensor. The research will apply synthetic biology and an interdisciplinary approach to develop a yeast-based GPCR biosensor for the engineering of enzymes and production hosts. The modular biosensor structure will allow any GPCR to be plugged in, enabling a variety of applications, both biomedical and environmental.

Coordinator

KOBENHAVNS UNIVERSITET
Net EU contribution
€ 207 312,00
Address
Norregade 10
1165 Kobenhavn
Denmark

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Region
Danmark Hovedstaden Byen København
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00