A novel Stratified Medicine Algorithm to predict treatment responses to host-directed therapy in TB patients.

Deliverables

Report on the Ethical issues

Report on the communication and dissemination activities No. 2

Report on all the communication and dissemination activities conducted until the month or delivery and list of those already planned for the next reporting period

Communication and Dissemination Plan

Communication and Dissemination Plan drafted, approved and published.

Update of the Communication and Dissemination Plan No. 1

Communication and Dissemination Plan with updates included if needed.

Update of the Communication and Dissemination Plan No. 2

Communication and Dissemination Plan with updates included if needed

Ethical Report No.1

Report on the Ethical issues.

Report on the communication and dissemination activities No. 1

Report on all the communication and dissemination activities conducted until the month or delivery and list of those already planned for the next reporting period.

Ethical Report No.2

Report on the Ethical issues

Project website

Website online.

Publications

Identification of the most vulnerable populations in the psychosocial sphere: a cross-sectional study conducted in Catalonia during the strict lockdown imposed against the COVID-19 pandemic

Author(s): Judith Farrés, José Luis Ruiz, José Manuel Mas, Lilibeth Arias, Maria-Rosa Sarrias, Carolina Armengol, Pere-Joan Cardona, José A. Muñoz-Moreno, Miriam Vilaplana, Belén Arranz, Judith Usall, Antoni Serrano-Blanco, Cristina Vilaplana
Published in: BMJ Open, Issue 11:e052140, 2021, ISSN 2044-6055
Publisher: BMJ Publishing Group
DOI: 10.1136/bmjopen-2021-052140

Multifaceted Roles of CD5L in Infectious and Sterile Inflammation

Author(s): Lidia Sanchez-Moral, Neus Ràfols, Clara Martori, Tony Paul, Érica Téllez, Maria-Rosa Sarrias
Published in: International Journal of Molecular Sciences, Issue 22/8, 2021, Page(s) 4076, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22084076

SMA-TB: study protocol for the phase 2b randomized double-blind, placebo-controlled trial to estimate the potential efficacy and safety of two repurposed drugs, acetylsalicylic acid and ibuprofen, for use as adjunct therapy added to, and compared with, the standard WHO recommended TB regimen

Author(s): Lilibeth Arias, Kennedy Otwombe, Ziyaad Waja, Nestani Tukvadze, Tamta Korinteli, Tumelo Moloantoa, Kaori L Fonseca, Natasha Pillay, Thabiso Seiphetlo, Dan Ouchi-Vernet, Adrian Siles, Lidia Carabias, Carles Quiñones, Sergo Vashakidze, Neil Martinson & Cristina Vilaplana
Published in: Trials, 2023, ISSN 1745-6215
Publisher: BioMed Central
DOI: 10.1186/s13063-023-07448-0

A Mycobacterium tuberculosis fingerprint in human breath allows tuberculosis detection

Author(s): Sergio Fabián Mosquera-Restrepo, Sophie Zuberogoïtia, Lucie Gouxette, Emilie Layre, Martine Gilleron, Alexandre Stella, David Rengel, Odile Burlet-Schiltz, Ana Cecilia Caro, Luis F. Garcia, César Segura, Carlos Alberto Peláez Jaramillo, Mauricio Rojas & Jérôme Nigou
Published in: Nature Communications, Issue 14 December 2022, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-35453-5

Accelerating research and development of new vaccines against tuberculosis: a global roadmap

Author(s): Frank Cobelens, Rajinder Kumar Suri, Michelle Helinski, Michael Makanga, Ana Lúcia Weinberg, Britta Schaffmeister, Frank Deege, Mark Hatherill; TB Vaccine Roadmap Stakeholder Group
Published in: The Lancet Infectious Diseases, 2022, ISSN 1473-3099
Publisher: The Lancet Publishing Group
DOI: 10.1016/s1473-3099(21)00810-0

Plasma LOX-Products and Monocyte Signaling Is Reduced by Adjunctive Cyclooxygenase-2 Inhibitor in a Phase I Clinical Trial of Tuberculosis Patients

Author(s): Marthe Jøntvedt Jørgensen, Kristin G. Nore, Hans Christian D. Aass, Emilie Layre, Jérôme Nigou, Rasmus Mortensen, Kjetil Tasken, Dag Kvale, Synne Jenum, Kristian Tonby, Anne Ma Dyrhol-Riise
Published in: Frontiers in Cellular and Infection Microbiology, Issue 11, 2021, ISSN 2235-2988
Publisher: Frontiers Media S. A.
DOI: 10.3389/fcimb.2021.669623

Immunological hyporesponsiveness in tuberculosis: The role of mycobacterial glycolipids

Author(s): Margarida Correia-Neves, Jérôme Nigou, Zaynab Mousavian, Christopher Sundling and Gunilla Källenius
Published in: Frontiers in Immunology, Issue Front. Immunol., 02 December 2022, 2022, ISSN 1664-3224
Publisher: Frontiers in immunology
DOI: 10.3389/fimmu.2022.1035122

Transcriptional profiles predict treatment outcome in patients with tuberculosis and diabetes at diagnosis and at two weeks after initiation of anti-tuberculosis treatment

Author(s): Cassandra L.R. van Doorn, Clare Eckold, Katharina Ronacher, Rovina Ruslami, Suzanne van Veen, Ji-Sook Lee, Vinod Kumar, Sarah Kerry-Barnard, Stephanus T. Malherbe, Léanie Kleynhans, Kim Stanley, Philip C. Hill, Simone A. Joosten, Reinout van Crevel, Cisca Wijmenga, Julia A. Critchley, Gerhard Walzl, Bachti Alisjahbana, Mariëlle C. Haks, Hazel M. Dockrell, Tom H.M. Ottenhoff, Eleonora Vianello, a
Published in: eBioMedicine, 2022, ISSN 2352-3964
Publisher: Elsevier BV
DOI: 10.1016/j.ebiom.2022.104173

Host‐directed therapy to combat mycobacterial infections*

Author(s): Gül Kilinç, Anno Saris, Tom H. M. Ottenhoff, Mariëlle C. Haks
Published in: Immunological Reviews, Issue 301/1, 2021, Page(s) 62-83, ISSN 0105-2896
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/imr.12951

The role of antibodies in tuberculosis diagnosis, prophylaxis and therapy: a review from the ESGMYC study group

Author(s): Solomon Tibebu Melkie, Lilibeth Arias, Chiara Farroni, Mateja Jankovic Makek, Delia Goletti, Cristina Vilaplana
Published in: European Respiratory Review, Issue 31, 2022, Page(s) 210218, ISSN 0905-9180
Publisher: European Respiratory Society
DOI: 10.1183/16000617.0218-2021

IN_CERT - The work process video

Author(s): Alcañiz, Adolf
Published in: 2022
Publisher: Adolf Alcañiz
DOI: 10.5281/zenodo.5884766

SMA-TB 1st Newsletter

Author(s): Maciejewska, Iwona; Arias de la Cruz, Lilibeth; Jérôme Nigou; Émilie Layre; Neil Martinson; Ziyaad Waja; Anne Margarita Dyrhol-Riise; Nestani Tukvadze; Sergo Vashakidze; Judith Farrés; Tom H.M. Ottenhoff; Mahavir Singh; Maria Rosa SarriasVilaplana, Cristina
Published in: Issue 1, 2020
Publisher: SMA-TB Consortium
DOI: 10.5281/zenodo.5503535

IN_CERT Programme

Author(s): Mercè Pomer; Queralt Morros; Roger Paredes; Cristina Vilaplana; Lourdes Mateu; Manel Guerrero; Jo Milne; Nora Ancarola; Adolf Alcañiz
Published in: 2021
Publisher: Ajuntament d'Alella
DOI: 10.5281/zenodo.5608507

Basic information on Tuberculosis to be shared during communication activities

Author(s): Nino Gogichadze; Cristina Vilaplana; Arnau Sagrera; Vira Buhiichyk; Joan Pau Millet; Raquel Prieto García; Jesús Edison Ospina; Laura Ginès; Pepón Meneses
Published in: Issue 1, 2022
Publisher: SMA-TB Consortium
DOI: 10.5281/zenodo.7476230

SMA-TB 2nd Newsletter

Author(s): Maciejewska, Iwona; Arias Lilibeth; Gogichadze, Nino; Nigou, Jérôme; Layre, Émilie; Martinson, Neil; Waja, Ziyaad; Dyrhol-Riise, Anne Margarita; Tukvadze, Nestani; Farrés, Judith; Ottenhoff, Tom H.M.; Singh, Mahavir; Sarrias, Maria-Rosa; Vashakidze, SergoVilaplana, Cristina
Published in: Issue 2, 2021
Publisher: SMA-TB Consortium
DOI: 10.5281/zenodo.5971772

Templates to be used in Project management and in Clinical Trial Monitoring

Author(s): Arias, Lilibeth, Vilaplana, Cristina, Fonseca, Kaori L., Martinson, Neil, Waja, Ziyaad, Vashakidze, Sergo, Tukvadze, Nestani, Korinteli, Tamta, Chirgadze, Tamar, & Witbooi, Denise
Published in: 2021
Publisher: SMA-TB Consortia
DOI: 10.5281/zenodo.7457938

Tot just veiem la llum al final del túnel - We are only just seeing the light at the end of the tunnel

Author(s): Cristina Vilaplana
Published in: IN_CERT (UN-CERTAIN): ART, SCIENCE AND THOUGHT SINCE THE PANDEMIC, Issue Oct 29, 2021, 2021, Page(s) 29-31, 127-128, 162-163
Publisher: Ajuntament d'Alella
DOI: 10.5281/zenodo.5897277

Deliverables

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