THERVACB: A THERAPEUTIC VACCINE TO CURE HEPATITIS B

Información del proyecto

TherVacB

Identificador del acuerdo de subvención: 848223

DOI

10.3030/848223

Fecha de la firma de la CE 6 Diciembre 2019

Fecha de inicio 1 Enero 2020

Fecha de finalización 31 Diciembre 2026

Financiado con arreglo a

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Coste total

€ 10 425 686,21

Aportación de la UE

€ 10 425 686,21

Coordinado por

HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
Germany

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Documents, reports (4)

Synopsis and protocol of the patient registry

In close cooperation with all WP partners MHH will provide a short protocol as well as the study synopsis of the patient registry.

Cross-network SOPs for immunoassays

SOPs for centralized and decentralized immunoassays available and in place; initial cross-validation of decentralized immunoassays to ensure inter-lab precision finished

Agreement of sample storage

HMGU will provide an informed consent form and an SOPs for sample preparation and storage (plasma and PBMCs) for all participating centers

Incidental Findings Policy

Report on the Incidental Findings Policy

Websites, patent fillings, videos etc. (1)

THERVACB web site and the relevant social media

Overview of the objectives of the THERVACB public website as part of the dissemination strategy, and its main functionalities, as well as an outline of the THERVACB social media strategy.

Publicaciones

Peer reviewed articles (11)

Perceptions of Stigma Among Patients With Hepatitis B in Germany: Cross-Sectional Survey

Autores: Bettina M Zimmermann, Theresa Willem, Michael Rost, Nina Matthes, Alena Buyx
Publicado en: JMIR Formative Research, Edición 9, 2025, Página(s) e66379-e66379, ISSN 2561-326X
Editor: JMIR Publications Inc.
DOI: 10.2196/66379

Social Media Recruitment as a Potential Trigger for Vulnerability: Multistakeholder Interview Study

Autores: Nina Matthes, Theresa Willem, Alena Buyx, Bettina M Zimmermann
Publicado en: JMIR Human Factors, Edición 11, 2024, Página(s) e52448-e52448, ISSN 2292-9495
Editor: JMIR Human Factors
DOI: 10.2196/52448

PD-L1 Silencing in Liver Using siRNAs Enhances Efficacy of Therapeutic Vaccination for Chronic Hepatitis B

Autores: Till Bunse, Anna D Kosinska, Thomas Michler, Ulrike Protzer
Publicado en: Biomolecules, Edición 12(3):470, 2022, ISSN 2218-273X
Editor: MDPI Open Access Journals
DOI: 10.3390/biom12030470

Practical Benefits, Challenges, and Recommendations on Social Media Recruitment: Multi-Stakeholder Interview Study

Autores: Goldman N, Willem T, Buyx A, Zimmermann B
Publicado en: Journal of Medical Internet Research, Edición 25:e44587, 2023, ISSN 1438-8871
Editor: Journal of medical Internet Research
DOI: 10.2196/44587

Acceptance of Social Media Recruitment for Clinical Studies Among Patients With Hepatitis B: Mixed Methods Study

Autores: Theresa Willem, Bettina M Zimmermann, Nina Matthes, Michael Rost, Alena Buyx
Publicado en: Journal of Medical Internet Research, Edición 26, 2024, Página(s) e54034, ISSN 1438-8871
Editor: Journal of medical Internet Research
DOI: 10.2196/54034

Social media advertising for clinical studies: Ethical and data protection implications of online targeting

Autores: Rainer Mühlhoff, Theresa Willem
Publicado en: Big Data & Society, Edición 10, 2023, Página(s) 205395172311561, ISSN 2053-9517
Editor: SAGE
DOI: 10.1177/20539517231156127

Ethical Issues in Social Media Recruitment for Clinical Studies: Ethical Analysis and Framework

Autores: Zimmermann BM, Willem T, Bredthauer CJ, Buyx A
Publicado en: J Med Internet Res, Edición 24 (5), 2022, ISSN 1438-8871
Editor: Journal of medical Internet Research
DOI: 10.2196/31231

Correction: Ethical Issues in Social Media Recruitment for Clinical Studies: Ethical Analysis and Framework

Autores: Bettina M Zimmermann; Theresa Willem; Carl Justus Bredthauer; Alena Buyx
Publicado en: J Med Internet Res, 2022, ISSN 1438-8871
Editor: Journal of medical Internet Research
DOI: 10.2196/40848

Immunogenicity and Antiviral Response of Therapeutic Hepatitis B Vaccination in a Mouse Model of HBeAg-Negative, Persistent HBV Infection

Autores: Kosinska, A.D.; Festag, J.; Mück-Häusl, M.; Festag, M.M.; Asen, T.; Protzer, U.
Publicado en: Vaccines, Edición 9(8), 841, 2021, ISSN 2076-393X
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines9080841

Activation of CD4 T cells during prime immunization determines the success of a therapeutic hepatitis B vaccine in HBV-carrier mouse models

Autores: Jinpeng Su, Livia Brunner, Edanur Ates Oz, Julia Sacherl, Geraldine Frank, Helene Anne Kerth, Frank Thiele, Marian Wiegand, Carolin Mogler, Julio Cesar Aguilar, Percy A. Knolle, Nicolas Collin, Anna D. Kosinska, Ulrike Protzer
Publicado en: Journal of Hepatology, 2023, ISSN 0168-8278
Editor: Elsevier BV
DOI: 10.1016/j.jhep.2022.12.013

Evaluation of the Effect of CD70 Co-Expression on CD8 T Cell Response in Protein-Prime MVA-Boost Vaccination in Mice

Autores: Ann-Sophie Stephan; Anna D. Kosinska; Martin Mück-Häusl; Andreas Muschaweckh; Clemens Jäger; Natalie Röder; Mathias Heikenwälder; Claudia Dembek; Ulrike Protzer
Publicado en: Volume 11, Edición 1, 2023, ISSN 2076-393X
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines11020245