THERVACB: A THERAPEUTIC VACCINE TO CURE HEPATITIS B

Informazioni relative al progetto

TherVacB

ID dell’accordo di sovvenzione: 848223

DOI

10.3030/848223

Data della firma CE 6 Dicembre 2019

Data di avvio 1 Gennaio 2020

Data di completamento 31 Dicembre 2026

Finanziato da

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Costo totale

€ 10 425 686,21

Contributo UE

€ 10 425 686,21

Coordinato da

HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
Germany

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (4)

Synopsis and protocol of the patient registry

In close cooperation with all WP partners MHH will provide a short protocol as well as the study synopsis of the patient registry.

Cross-network SOPs for immunoassays

SOPs for centralized and decentralized immunoassays available and in place; initial cross-validation of decentralized immunoassays to ensure inter-lab precision finished

Agreement of sample storage

HMGU will provide an informed consent form and an SOPs for sample preparation and storage (plasma and PBMCs) for all participating centers

Incidental Findings Policy

Report on the Incidental Findings Policy

Websites, patent fillings, videos etc. (1)

THERVACB web site and the relevant social media

Overview of the objectives of the THERVACB public website as part of the dissemination strategy, and its main functionalities, as well as an outline of the THERVACB social media strategy.

Pubblicazioni

Peer reviewed articles (11)

Perceptions of Stigma Among Patients With Hepatitis B in Germany: Cross-Sectional Survey

Autori: Bettina M Zimmermann, Theresa Willem, Michael Rost, Nina Matthes, Alena Buyx
Pubblicato in: JMIR Formative Research, Numero 9, 2025, Pagina/e e66379-e66379, ISSN 2561-326X
Editore: JMIR Publications Inc.
DOI: 10.2196/66379

Social Media Recruitment as a Potential Trigger for Vulnerability: Multistakeholder Interview Study

Autori: Nina Matthes, Theresa Willem, Alena Buyx, Bettina M Zimmermann
Pubblicato in: JMIR Human Factors, Numero 11, 2024, Pagina/e e52448-e52448, ISSN 2292-9495
Editore: JMIR Human Factors
DOI: 10.2196/52448

PD-L1 Silencing in Liver Using siRNAs Enhances Efficacy of Therapeutic Vaccination for Chronic Hepatitis B

Autori: Till Bunse, Anna D Kosinska, Thomas Michler, Ulrike Protzer
Pubblicato in: Biomolecules, Numero 12(3):470, 2022, ISSN 2218-273X
Editore: MDPI Open Access Journals
DOI: 10.3390/biom12030470

Practical Benefits, Challenges, and Recommendations on Social Media Recruitment: Multi-Stakeholder Interview Study

Autori: Goldman N, Willem T, Buyx A, Zimmermann B
Pubblicato in: Journal of Medical Internet Research, Numero 25:e44587, 2023, ISSN 1438-8871
Editore: Journal of medical Internet Research
DOI: 10.2196/44587

Acceptance of Social Media Recruitment for Clinical Studies Among Patients With Hepatitis B: Mixed Methods Study

Autori: Theresa Willem, Bettina M Zimmermann, Nina Matthes, Michael Rost, Alena Buyx
Pubblicato in: Journal of Medical Internet Research, Numero 26, 2024, Pagina/e e54034, ISSN 1438-8871
Editore: Journal of medical Internet Research
DOI: 10.2196/54034

Social media advertising for clinical studies: Ethical and data protection implications of online targeting

Autori: Rainer Mühlhoff, Theresa Willem
Pubblicato in: Big Data & Society, Numero 10, 2023, Pagina/e 205395172311561, ISSN 2053-9517
Editore: SAGE
DOI: 10.1177/20539517231156127

Ethical Issues in Social Media Recruitment for Clinical Studies: Ethical Analysis and Framework

Autori: Zimmermann BM, Willem T, Bredthauer CJ, Buyx A
Pubblicato in: J Med Internet Res, Numero 24 (5), 2022, ISSN 1438-8871
Editore: Journal of medical Internet Research
DOI: 10.2196/31231

Correction: Ethical Issues in Social Media Recruitment for Clinical Studies: Ethical Analysis and Framework

Autori: Bettina M Zimmermann; Theresa Willem; Carl Justus Bredthauer; Alena Buyx
Pubblicato in: J Med Internet Res, 2022, ISSN 1438-8871
Editore: Journal of medical Internet Research
DOI: 10.2196/40848

Immunogenicity and Antiviral Response of Therapeutic Hepatitis B Vaccination in a Mouse Model of HBeAg-Negative, Persistent HBV Infection

Autori: Kosinska, A.D.; Festag, J.; Mück-Häusl, M.; Festag, M.M.; Asen, T.; Protzer, U.
Pubblicato in: Vaccines, Numero 9(8), 841, 2021, ISSN 2076-393X
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines9080841

Activation of CD4 T cells during prime immunization determines the success of a therapeutic hepatitis B vaccine in HBV-carrier mouse models

Autori: Jinpeng Su, Livia Brunner, Edanur Ates Oz, Julia Sacherl, Geraldine Frank, Helene Anne Kerth, Frank Thiele, Marian Wiegand, Carolin Mogler, Julio Cesar Aguilar, Percy A. Knolle, Nicolas Collin, Anna D. Kosinska, Ulrike Protzer
Pubblicato in: Journal of Hepatology, 2023, ISSN 0168-8278
Editore: Elsevier BV
DOI: 10.1016/j.jhep.2022.12.013

Evaluation of the Effect of CD70 Co-Expression on CD8 T Cell Response in Protein-Prime MVA-Boost Vaccination in Mice

Autori: Ann-Sophie Stephan; Anna D. Kosinska; Martin Mück-Häusl; Andreas Muschaweckh; Clemens Jäger; Natalie Röder; Mathias Heikenwälder; Claudia Dembek; Ulrike Protzer
Pubblicato in: Volume 11, Numero 1, 2023, ISSN 2076-393X
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines11020245