Monoclonal Antibodies with Binding Sensitive To Environmental Regulation

Publications

Generation of Multivalent Nanobody-Based Proteins with Improved Neutralization of Long α-Neurotoxins from Elapid Snakes

Auteurs: Jack Wade, Charlotte Rimbault, Hanif Ali, Line Ledsgaard, Esperanza Rivera-de-Torre, Maher Abou Hachem, Kim Boddum, Nadia Mirza, Markus-Frederik Bohn, Siri A. Sakya, Fulgencio Ruso-Julve, Jan Terje Andersen, Andreas H. Laustsen
Publié dans: Bioconjugate Chemistry, 2022, ISSN 1043-1802
Éditeur: American Chemical Society
DOI: 10.1021/acs.bioconjchem.2c00220

The rise of genomics in snake venom research: recent advances and future perspectives

Auteurs: Wei-qiao Rao, Konstantinos Kalogeropoulos, Morten E Allentoft, Shyam Gopalakrishnan, Wei-ning Zhao, Christopher T. Workman, Cecilie Knudsen, Belén Jiménez-Mena, Lorenzo Seneci, Mahsa Mousavi-Derazmahalleh, Timothy P Jenkins, Esperanza Rivera-de-Torre, Si-qi Liu, Andreas H. Laustsen
Publié dans: GigaScience, 2022, ISSN 2047-217X
Éditeur: Oxford Academic
DOI: 10.1093/gigascience/giac024

Causes and Consequences of Snake Venom Variation

Auteurs: Nicholas R. Casewell, Timothy N.W. Jackson, Andreas H. Laustsen, Kartik Sunagar
Publié dans: Trends in Pharmacological Sciences, 2020, ISSN 2423-3722
Éditeur: Elsevier
DOI: 10.1016/j.tips.2020.05.006

Neutralization capacity of recombinant antivenoms based on monoclonal antibodies and nanobodies

Auteurs: Anne Ljungars, Andreas H. Laustsen
Publié dans: Toxicon, 2022, Page(s) 106991, ISSN 0041-0101
Éditeur: Pergamon Press
DOI: 10.1016/j.toxicon.2022.106991

Synthetic antibodies block receptor binding and current‐inhibiting effects of α‐cobratoxin from <i>Naja kaouthia</i>

Auteurs: Shane Miersch; Guillermo de la Rosa; Rasmus Friis; Line Ledsgaard; Kim Boddum; Andreas H. Laustsen; Sachdev S. Sidhu
Publié dans: Protein Science, 2022, ISSN 1469-896X
Éditeur: Wiley
DOI: 10.1002/pro.4296

In vitro discovery of a human monoclonal antibody that neutralizes lethality of cobra snake venom

Auteurs: Line Ledsgaard, Andreas H. Laustsen, Urska Pus, Jack Wade, Pedro Villar, Kim Boddum, Peter Slavny, Edward W. Masters, Ana S. Arias, Saioa Oscoz, Daniel T. Griffiths, Alice M. Luther, Majken Lindholm, Rachael A. Leah, Marie Sofie Møller, Hanif Ali, John McCafferty, Bruno Lomonte, José M. Gutiérrez, Aneesh Karatt-Vellatt
Publié dans: mAbs, 2022, ISSN 1942-0862
Éditeur: Taylor & Francis
DOI: 10.1080/19420862.2022.2085536

Advances in antibody phage display technology

Auteurs: Line Ledsgaard, AnneLjungars, Charlotte Rimbault, Christoffer V. Sørensen, Tulika Tulika, Jack Wade, Yessica Wouters, John McCafferty, Andreas H. Laustsen
Publié dans: Drug Discovery Today, 2022, ISSN 1359-6446
Éditeur: Elsevier BV
DOI: 10.1016/j.drudis.2022.05.002

Current Knowledge on Snake Dry Bites

Auteurs: Manuela B. Pucca, Cecilie Knudsen, Isadora S. Oliveira, Charlotte Rimbault, Felipe A. Cerni, Fan Hui Wen, Jacqueline Sachett, Marco A. Sartim, Andreas H. Laustsen, Wuelton M. Monteiro
Publié dans: Toxins, 2020, ISSN 2072-6651
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/toxins12110668

Strategies for Heterologous Expression, Synthesis, and Purification of Animal Venom Toxins

Auteurs: Esperanza Rivera-de-Torre; Charlotte Rimbault; Timothy P. Jenkins; Christoffer V. Sørensen; Anna Damsbo; Natalie J. Saez; Yoan Duhoo; Celeste Menuet Hackney; Lars Ellgaard; Andreas H. Laustsen
Publié dans: Frontiers in Bioengineering and Biotechnology, 2022, ISSN 2296-4185
Éditeur: Frontiers Media
DOI: 10.3389/fbioe.2021.811905

Animal Immunization, in Vitro Display Technologies, and Machine Learning for Antibody Discovery.

Auteurs: Andreas Hougaard Laustsen; Victor Greiff; Aneesh Karatt-Vellatt; Serge Muyldermans; Timothy P. Jenkins
Publié dans: Trends in Biotechnology, 2021, ISSN 1879-3096
Éditeur: Elsevier
DOI: 10.1016/j.tibtech.2021.03.003

The challenges with developing therapeutic monoclonal antibodies for pandemic application

Auteurs: Andreas H. Laustsen, Markus-Frederik Bohn, Anne Ljungars
Publié dans: Expert Opinion on Drug Discovery, 2021, ISSN 1746-0441
Éditeur: Informa Healthcare
DOI: 10.1080/17460441.2021.1976141

AHA: AI-guided tool for the quantification of venom-induced haemorrhage in mice

Auteurs: Timothy P. Jenkins1, William Michael Laprade, Andrés Sánchez, Tulika Tulika, Carol O’Brien, Christoffer V. Sørensen, Trenton K. Stewart, Thomas Fryer, Andreas H. Laustsen, José María Gutiérrez
Publié dans: Frontiers in Tropical Diseases, 2022, ISSN 2673-7515
Éditeur: Frontiers
DOI: 10.3389/fitd.2022.1063640

Terrestrial venomous animals, the envenomings they cause, and treatment perspectives in the Middle East and North Africa.

Auteurs: Timothy P. Jenkins; Shirin Ahmadi; Mátyás A. Bittenbinder; Mátyás A. Bittenbinder; Trenton K Stewart; Dilber E Akgun; Melissa Hale; Nafiseh Nasri Nasrabadi; Nafiseh Nasri Nasrabadi; Darian S Wolff; Freek J. Vonk; Freek J. Vonk; Jeroen Kool; Andreas Hougaard Laustsen
Publié dans: PLOS Neglected Tropical Diseases, 2021, ISSN 1935-2727
Éditeur: Public Library of Science
DOI: 10.1371/journal.pntd.0009880

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