Artificial cell creation via DNA nanotechnology
A fundamental challenge when creating an artificial cell by synthetic biology is the poor control of replication machinery borrowed from living cells. DNA nanotechnology enables a bottom-up approach for the truly novel design of nanoscale objects through well controlled programmable processes. This EU-funded project will establish a fully integrated platform based on DNA nanotechnology to create a functional artificial cell with the design of DNA-based objects mimicking cellular organelles performing specific functions. These artificial organelles will have capability for self-assembly followed by encapsulation into lipid bilayers compartments resulting in the formation of artificial cells with specific functional characteristics. Applications abound in biosensing and smart therapeutics.
Fields of science
Call for proposal
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