Risultati finali
The Purified Mtb cytochrome report will describe the methodology and confirmation of the purified cytochrome bc1, bc1:aa3, and bd
Continuous enzymatic assay and screening reportThe continuous enzymatic assay and screening report will describe the assay, conditions and characterisation methodology of the continuous enzymatic assay for testing Mtr inhibitors and the application in the High Throughput Screening campaign.
In vitro activity of single HDT compounds reportIn vitro activity of single HDT compounds report will summarize the results of in vitro activity of single Host Directed Therapeutics compounds against intracellular MDRMtb strains in human cells
The website developed for communication of all RespiriTB activities will be active and online.
Pubblicazioni
Autori:
Gül Kilinç, Anno Saris, Tom H. M. Ottenhoff, Mariëlle C. Haks
Pubblicato in:
Immunological Reviews, Numero 301/1, 2021, Pagina/e 62-83, ISSN 0105-2896
Editore:
Blackwell Publishing Inc.
DOI:
10.1111/imr.12951
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