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Controlling epileptic brain networks with computationally optimized weak electric fields

Project description

Advancing the treatment of epilepsy

Epilepsy treatment fails in nearly one third of patients, leaving millions suffering from drug-resistant epileptic episodes. Non-invasive brain transcranial current stimulation (tCS) is emerging as a promising solution, but poor understanding of its short- and long-term effects limits its application. The EU-funded GALVANI project is investigating the impact weak electric fields have on the physiology of neurons and neural networks. The key objective is to understand if these electric pulses can improve the patient-specific epileptogenic network. The project will generate mechanistic insight that will be combined with computational models to develop personalised tCS protocols and prevent epileptic seizures.

Field of science

  • /natural sciences/biological sciences/biophysics
  • /natural sciences/biological sciences/neurobiology/computational neuroscience
  • /medical and health sciences/basic medicine/neurology/epilepsy

Call for proposal

ERC-2019-SyG
See other projects for this call

Funding Scheme

ERC-SyG - Synergy grant

Host institution

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
Address
Rue De Tolbiac 101
75654 Paris
France
Activity type
Research Organisations
EU contribution
€ 3 368 631,25

Beneficiaries (3)

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
EU contribution
€ 3 368 631,25
Address
Rue De Tolbiac 101
75654 Paris
Activity type
Research Organisations
UNIVERSITE D'AIX MARSEILLE
France
EU contribution
€ 3 700 732,75
Address
Boulevard Charles Livon 58
13284 Marseille
Activity type
Higher or Secondary Education Establishments
NEUROELECTRICS BARCELONA SL
Spain
EU contribution
€ 2 928 813
Address
Av. Tibidabo 47 Bis
08035 Barcelona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)