Deliverables Documents, reports (11) Elaboration and approval (by UC Rector) of internal regulations and bylaws Elaboration and approval (by UC Rector) of internal regulations and bylaws. Initial teams in place: Installation Committee, Science and Business Council, International Advisory Board, Advocacy Committee, Ethics Advisory Board Initial teams in place; Instalation Committee, Science and Business Council, International Advisory Board, Advocacy Committee, Ethics Advisory Board. Report on web site development and performance Report on web site development and performance Report on translational / clinics research for MIA- Portugal Report on translational clinics research for MIAPortugal MIA-Portugal Communication, Exploitation and Dissemination Plan, and Dissemination Booklet MIAPortugal Communication Exploitation and Dissemination Plan and Dissemination Booklet Subscription of internal regulations by the ERA Chair team Subscription of internal regulations by the ERA Chair team Events - M12 Report of scientific, translational, innovation and societal events (M12). Report on Common Advanced Teaching Synergies with Teaming Partners Report on Common Advanced Teaching Synergies with Teaming Partners MIA-Portugal management team in place MIAPortugal management team in place Events - M24 Report of scientific translational innovation and societal events M24 Recruitment of 7 MIA-Portugal research groups (excluding the ERA Chair) Recruitment of 7 MIAPortugal research groups excluding the ERA Chair Websites, patent fillings, videos etc. (2) Recruitment of MIA-Portugal Scientific Director Recruitment of MIAPortugal Scientific Director MIA-Portugal flyer MIA-Portugal flyer Publications Book chapters (2) Exocytotic SNARE complex assembly, disassembly, and regulation Author(s): Milosevic, I., & Knight, J. D. Published in: 2022 Publisher: IOP Science DOI: 10.1088/978-0-7503-3771-7ch3 Disrupted cellular quality control mechanisms in aging Author(s): Cristina Carvalho; Joana F. Pires; Paula I. Moreira; Nuno Raimundo Published in: Crossref, Issue 5, 2022 Publisher: Elsevier DOI: 10.1016/b978-0-12-823761-8.00016-1 Peer reviewed articles (7) Counteracting Colon Cancer by Inhibiting Mitochondrial Respiration and Glycolysis with a Selective PKCδ Activator Author(s): Bessa, C; Loureiro, JB; Barros, M; Isca, VMS; Sardao, VA; Oliveira, PJ; Bernardino, RL; Herman-de-Sousa, C; Costa, MA; Correia-de-Sa, P; Alves, MG; Rijo, P; Saraiva, L Published in: International Journal of Molecular Sciences, 2023, ISSN 1661-6596 Publisher: MDPI DOI: 10.3390/ijms24065710 Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3 Author(s): Upmanyu N, Jin J, Emde HV, Ganzella M, Bösche L, Malviya VN, Zhuleku E, Politi AZ, Ninov M, Silbern I, Leutenegger M, Urlaub H, Riedel D, Preobraschenski J, Milosevic I, Hell SW, Jahn R, Sambandan S. Published in: https://www.sciencedirect.com/science/article/pii/S0896627322001465, 2022, ISSN 0896-6273 Publisher: Cell Press DOI: 10.1016/j.neuron.2022.02.008 Extracellular vesicles improve GABAergic transmission in Huntington's disease iPSC-derived neurons Author(s): Beatriz M, Rodrigues RJ, Vilaça R, Egas C, Pinheiro PS, Daley GQ, Schlaeger TM, Raimundo N, Rego AC, Lopes C. Published in: Theranostics, 2023, ISSN 1838-7640 Publisher: Ivyspring International Publisher DOI: 10.7150/thno.81981 Fine-tuning activity-dependent bulk endocytosis via kinases and phosphatases. Author(s): Ira Milosevic; Ira Milosevic; Michael A. Cousin Published in: reponame:Repositório Científico de Acesso Aberto de Portugal, Issue 1, 2021, ISSN 0021-9525 Publisher: Rockefeller University Press DOI: 10.1083/jcb.202111056 Lack of peroxisomal catalase affects heat shock response in<i>Caenorhabditis elegans</i> Author(s): Marina Musa; Pedro A Dionisio; Ricardo Casqueiro; Ira Milosevic; Nuno Raimundo; Anita Krisko Published in: Crossref, Issue 9, 2022, ISSN 2575-1077 Publisher: Life Science Alliance DOI: 10.26508/lsa.202201737 A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients. Author(s): Cláudia M. Deus; Susana P. Pereira; Teresa Cunha-Oliveira; José A. Teixeira; Rui F. Simões; Fernando Cagide; Sofia Benfeito; Fernanda Borges; Nuno Raimundo; Paulo J. Oliveira Published in: Redox Biology, Vol 45, Iss , Pp 102037- (2021), Issue 18, 2021, ISSN 2213-2317 Publisher: Elsevier BV DOI: 10.1016/j.redox.2021.102037 Brassica oleracea Var italica by-Products Prevent Lipid Accumulation and Cell Death in a Liver Cell Model of Lipid Toxicity Author(s): José P. Castelão-Baptista, Sara A. Valente, Sara Canário, David Oppolzer, Ana Barros, Carlos Venâncio, Tânia Martins, Luís Antunes,Vilma A. Sardão, Eduardo Rosa, and Paulo J. Oliveira Published in: Nutrients, 2023, ISSN 2072-6643 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/nu15040924 Other (12) Cellular senescence: from mechanisms to current biomarkers and senotherapies Author(s): Vasco Lucas, Cláudia Cavadas and Célia Alexandra Aveleira Published in: 2023 Publisher: American Society for Pharmacology and Experimental Therapy DOI: 10.1124/pharmrev.122.000622 Primary cilia shape hallmarks of health and aging Author(s): Silva, DF; Cavadas, C Published in: 2023 Publisher: Elsevier DOI: 10.1016/j.molmed.2023.04.001 Modulation of signaling pathways by DJ-1: An updated overview Author(s): Neves, M; Graos, M; Anjo, SI; Manadas, B Published in: 2022 Publisher: Elsevier DOI: 10.1016/j.redox.2022.102283 The impact of insomnia on frailty and the hallmarks of aging Author(s): Catarina Carvalhas-Almeida, Cláudia Cavadas & Ana Rita Álvaro Published in: Aging Clinical and Experimental Research, 2023, ISSN 1594-0667 Publisher: Springer Verlag DOI: 10.1007/s40520-022-02310-w How good is the evidence that cellular senescence causes skin ageing? Author(s): Low, E; Alimohammadiha, G; Smith, LA; Costello, LF; Przyborski, SA; Von Zglinicki, T; Miwa, S Published in: 2021 Publisher: Elsevier Ireland DOI: 10.1016/j.arr.2021.101456 Modulation of cellular redox environment as a novel therapeutic strategy for Parkinson's disease Author(s): Deus CM, Teixeira J, Raimundo N, Tucci P, Borges F, Saso L, Oliveira PJ Published in: Eur Journal of Clinical Investigation, 2022 Publisher: Book in Press DOI: 10.1111/eci.13820 Metabolic Priming as a Tool in Redox and Mitochondrial Theragnostics Author(s): Pinho, SA; Anjo, SI; Cunha-Oliveira, T Published in: Antioxidants, 2023 Publisher: MDPI DOI: 10.3390/antiox12051072 Exercise-Boosted Mitochondrial Remodeling in Parkinson’s Disease Author(s): Magaña, JC; Deus, CM; Giné-Garriga, M; Montané, J; Pereira, SP Published in: 2022 Publisher: MDPI DOI: 10.3390/biomedicines10123228 Mitochondrial dysfunction in cell senescence and aging Author(s): Miwa, S; Kashyap, S; Chini, E; von Zglinicki, T Published in: 2022 Publisher: American Society for Clinical Investigation DOI: 10.1172/jci158447 The role of microRNAs in proteostasis decline and protein aggregation during brain and skeletal muscle aging Author(s): Stephany Francisco, Vera Martinho, Margarida Ferreira, Andreia reis, Gabriela Moura, Ana Raquel Soares and Manuel A. S. Santos Published in: Int. J. Mol.Sci, Issue PMID: 35328652 PMCID: PMC8955204, 2022 Publisher: Int. J. Mol.Sci DOI: 10.3390/ijms23063232 SIRT1 activation and its circadian clock control: a promising approach against (frailty in) neurodegenerative disorders Author(s): Ribeiro, RFN; Pereira, D; De Almeida, LP; Silva, MMC; Cavadas, C Published in: 2022 Publisher: Springer Science and Business Media Deutschanld GMBH DOI: 10.1007/s40520-022-02257-y From Non-Alcoholic Fatty Liver to Hepatocellular Carcinoma: A Story of (Mal)Adapted Mitochondria Author(s): Ricardo Amorim, Carina C. Magalhães, Fernanda Borges, Paulo J. Oliveira, andJosé Teixeira Published in: 2023 Publisher: Biology (Basel) DOI: 10.3390/biology12040595 Non-peer reviewed articles (1) The effect of estradiol during the early stages of osteoclast differentiation is associated with the accumulation of phosphorylated p53 in mitochondria and the inhibition of mitochondrial metabolism Author(s): Adriana Marques-Carvalho, Beatriz Silva, Francisco B. Pereira, Ha-Neui Kim, Maria Almeida, Vilma A. Sardão Published in: bioRxiv, 2023, ISSN 2692-8205 Publisher: bioRxiv DOI: 10.1101/2023.03.30.534893 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
