Description du projet
Un front uni pour combattre la coalescence des bactéries dangereuses dans les stations de traitement des eaux usées
Les stations de traitement des eaux usées sécurisent la libération des eaux usées dans l’environnement. Malheureusement, elles sont également l’une des plus grandes sources de bactéries résistantes aux antibiotiques (ARB). Les microbes provenant des humains, des animaux et de l’environnement, dont un grand nombre abrite des gènes de résistance aux antibiotiques, entrainant ainsi une surutilisation des antibiotiques, convergent dans un système confiné. La collecte standardisée des données et les analyses standardisées concernant les ARB et les gènes associés présents dans les eaux usées sont essentielles pour gérer de manière efficace les risques environnementaux et les risques pour la santé publique à venir. REPARES répondra à un besoin critique, en soutenant la compétence et le financement universitaires, tout en créant le cadre structurel pour la coopération avec les organismes gouvernementaux et publics par le biais de bases de données intégrées, d’une plateforme web, et de nombreuses activités d’information et de rayonnement.
Objectif
Development and proliferation of antibiotic resistance is classified among major global threats by the World Health Organization. Sanitation of the water cycle is essential to sustain environmental and human health. Within urban water systems, public and governmental perception is rising on the role of wastewater treatment plants (WWTPs) and their microbiomes as putative hotspots for the proliferation of antibiotic resistances, and the need for new quality criteria and installation upgrades.
However, because of methodological biases, our knowledge remains limited on the emission, fate and possible amplification or removal of antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARGs) across WWTPs. There is an urgent need to develop standardized methods and database for the accurate identification, characterization, and quantification of antibiotic resistances in such complex water matrices.
REPARES brings excellence in research on spread of antibiotic resistance in WWTPs through establishing cooperation of UCT with leading European innovators and internationally-renowned expert of the water-related antibiotic resistance field: UCP will share its expert leadership in wastewater-mediated antibiotic resistance; TUDelft will deliver methods to successfully apply for international projects; Wetsus will propel cooperation with the non-academic sector; AAU will integrate the REPARES database within the world-accepted MiDAS database.
REPARES aims at advancing the European community‘s know-how on antibiotic resistance across sanitation waterways, which in the future will bring society to closer achieve Sustainable Development Goal of the United Nations. REPARES will act as an essential vector to disseminate information on antimicrobial resistance spread within European WWTPs beyond science and technology in order to reach the non-academic community by means of open events, popularization publications, and operation of the REPARES web platform.
Champ scientifique
- engineering and technologyenvironmental engineeringwater treatment processeswastewater treatment processes
- natural sciencescomputer and information sciencesdatabases
- natural sciencesbiological sciencesmicrobiologybacteriology
- medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsantibiotics
- medical and health sciencesbasic medicinepharmacology and pharmacydrug resistanceantibiotic resistance
Mots‑clés
Programme(s)
- H2020-EU.4.b. - Twinning of research institutions Main Programme
Thème(s)
Régime de financement
CSA - Coordination and support actionCoordinateur
166 28 Praha
Tchéquie