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Targeted Anti-Cancer Therapies

Deliverables

completion of the network-wide meetings' schedules

Schedules of all networkwide meetings will be issued every 8 months starting at month 7 As networkwide meetings will be conducted at various locations there will be several lead beneficiaries namely WU UCL QUB AD UNISTRA and HDPR

bimonthly newsletter launched

A newsletter detailling the most representative achievements of the consortium and giving news about the progress of the project As mutual lead beneficiaries of WP7 both AD and UNISTRA are the actual lead beneficiaries of this deliverable

meetings reports

Report of all essential aspects discussed during the networkwide meetings whether they be scientific or not Sensitive results will not be disclosed as this report will be made public Reports will be made every 8 months until month 40

kick-off press release

A document sent to the press that officially announces the beginning of the project. As mutual lead beneficiaries of WP7, both AD and UNISTRA are the actual lead beneficiaries of this deliverable.

completion of the PM recruitment

Recruitment of a Project Manager.

completion of the ESRs recruitment

All ESRs recruited and ready to start their PhD projects. All beneficiaries should be lead beneficiaries for this deliverable.

TACT's yearly participation in at least one public event

TACT ESRs will participate in at least one big public event every year such as a charity Movember Breast Cancer Awareness Month etc or science festivals open days etc The due dates are succeptible to change depending on the date of the corresponding event All beneficiaries should be lead beneficiaries for this deliverable

online website and social media accounts

Website of the TACT project and all social media accounts connected to it

Publications

A novel thiol-labile cysteine protecting group for peptide synthesis based on a pyridazinedione (PD) scaffold

Author(s): R.J. Spears; Clíona McMahon; Monika Shamsabadi; Calise Bahou; Ioanna A. Thanasi; Léa N. C. Rochet; Nafsika Forte; Fabien Thoreau; James R. Baker; Vijay Chudasama
Published in: Chemical Communications, 2022, Page(s) Chem. Commun., 2022, 58, 645-648, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1cc03802h

[2]-Ladderanes as isosteres for meta-substituted aromatic rings and rigidified cyclohexanes

Author(s): Rachel C. Epplin, Shashwati Paul, Loïc Herter, Christophe Salome, Erin N. Hancock, Jay F. Larrow, Erich W. Baum, David R. Dunstan, Carol Ginsburg-Moraff, Thomas C. Fessard, M. Kevin Brown
Published in: Nature Communications, 2022, Page(s) 1-5, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-33827-3

Preparation of new bicyclo[2.1.1]hexane compact modules: an opening towards novel sp3-rich chemical space

Author(s): Loïc Herter, Ilias Koutsopetras, Lorenzo Turelli, Thomas Fessard*, Christophe Salomé*
Published in: Organic & Biomolecular Chemistry, 2022, Page(s) 9108-9111, ISSN 1477-0520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2ob01669a

Strain-Release [2π + 2σ] Cycloadditions for the Synthesis of Bicyclo[2.1.1]hexanes Initiated by Energy Transfer

Author(s): Renyu Guo, Yu-Che Chang, Loic Herter, Christophe Salome, Sarah E. Braley, Thomas C. Fessard, and M. Kevin Brown
Published in: Journal of the American Chemical Society, 2022, Page(s) J. Am. Chem. Soc. 2022, 144, 18, 7988–7994, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.2c02976

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