Skip to main content

Next Generation Instrument for In-Depth Analysis of Mitochondrial Fitness

Deliverables

Intermediate Communication Plan

Report containing updated communication strategy and activities performed during Year 1 of the project.

Website

Updated website with a dedicated section for NextGen-O2k Phase 2 project.

Searching for OpenAIRE data...

Publications

O2k-Specifications for respirometry and comprehensive OXPHOS analysis

Author(s): Gnaiger E
Published in: Mitochondrial Physiology Network, Issue 18.10(09), 2019, Page(s) 1-8

O2k Quality Control 2: Instrumental oxygen background correction and accuracy of oxygen flux

Author(s): Fasching M, Gnaiger E
Published in: Mitochondrial Physiology Network, Issue 14.06(08), 2020, Page(s) 1-16

NextGen-O2k: Q-Module Manual

Author(s): Komlodi T, Cardoso LHD, Gollner M, Merth A, Hunger M, Iglesias-Gonzalez J, Doerrier C, Tindle-Solomon L, Schwaninger H, Walter-Vracevic M, Gradl P, Moore AL, Gnaiger E
Published in: Mitochondrial Physiology Network, Issue 24.12(02), 2020, Page(s) 1-21

DatLab 8.0: Cyclic voltammetry manual

Author(s): Komlodi T, Cardoso LHD, Haider M, Tindle-Solomon L, Iglesias-Gonzalez J, Gnaiger E
Published in: Mitochondrial Physiology Network, Issue 24.16(01), 2019, Page(s) 1-10

Oxygen flux analysis with DatLab 7.4

Author(s): Cardoso LHD, Antunes D, Iglesias-Gonzalez J, Komlodi T, Doerrier C, Garcia-Souza LF, Gnaiger E, Sobotka O
Published in: Mitochondrial Physiology Network, Issue 24.06(02), 2020, Page(s) 1-11

Hydrogen peroxide flux analysis using Amplex Ultra Red assay in MiR05-Kit with DatLab 7.4

Author(s): Komlodi T, Iglesias-Gonzalez J, Cardoso LHD, Sobotka O, Gnaiger E
Published in: Mitochondrial Physiology Network, Issue 24.10(02), 2020, Page(s) 1-6

Data analysis of mitochondrial membrane potential estimation using safranin

Author(s): Komlodi T, Fasching M, Antunes D, Iglesias-Gonzalez J, Sobotka O, Gnaiger E
Published in: Mitochondrial Physiology Network, Issue 24.08(02), 2020, Page(s) 1-8

Data analysis of mitochondrial membrane potential estimation using various fluorescence dyes

Author(s): Komlodi T, Antunes D, Iglesias-Gonzalez J, Sobotka O, Gnaiger E
Published in: Mitochondrial Physiology Network, Issue 24.09(02), 2020, Page(s) 1-5

Mitochondrial respiratory states and rates

Author(s): Gnaiger E, Aasander Frostner E, Abdul Karim N, Abdel-Rahman EA, Abumrad NA, Acuna-Castroviejo D, Adiele RC, Ahn B, Alencar MB, Ali SS, Almeida A, Alton L, Alve sMG, Amati F, Amoedo ND, Amorim R, Andreadou I, Antunes D, Aragó M, Aral C, Arandarčikaitė O,Arias Reyes C, Armand AS, Arnould T, Avram VF, Bailey DM, Bairam A, Bajpeyi S, Bajzikova M, Bakker BM, Banni A, Bardal T, Barlow J, Bastos Sant'
Published in: MitoFit Preprint Archives, 2019

Mitochondrial physiology

Author(s): Gnaiger E, Aasander Frostner E, Abdul Karim N, Abdel-Rahman EA, Abumrad NA, Acuna-Castroviejo D, Adiele RC, Ahn B, Alencar MB, Ali SS, Almeida A, Alton L, Alve sMG, Amati F, Amoedo ND, Amorim R, Andreadou I, Antunes D, Aragó M, Aral C, Arandarčikaitė O,Arias Reyes C, Armand AS, Arnould T, Avram VF, Bailey DM, Bairam A, Bajpeyi S, Bajzikova M, Bakker BM, Banni A, Bardal T, Barlow J, Bastos Sant'
Published in: Bioenergetics Communications, 2020

Inter-laboratory harmonization of respiratory protocols in permeabilized human muscle fibers

Author(s): Doerrier C, Gama-Perez P, Distefano G, Pesta D, Soendergaard SD, Chroeis KM, Gonzalez-Franquesa A, Goodpaster BH, Coen P, Larsen S, Gnaiger E, Garcia-Roves PM
Published in: MitoFit Preprint Archives, 2019

Partitioning between cytochrome c oxidase and alternative oxidase studied by oxygen kinetics of dark respiration in Chlamydomonas reinhardtii: a microalgae model organism

Author(s): Di Marcello M, Iglesias-Gonzalez J, Meszaros A, Haider M, Gnaiger E, Huete-Ortega M
Published in: MitoFit Preprint Archives, 2019

Generating reference values on mitochondrial respiration in permeabilized muscle fibers

Author(s): Chabi Béatrice, Ost M, Gama-Perez P, Dahdah N, Lemieux H, Holody CD, Carpenter RG, Tepp K, Puurand M, Kaambre T, Dubouchaud H, Cortade F, Pesta D, Calabria E, Casado M, Fernandez-Ortiz M, Acuña-Castroviejo D, Villena JA, Grefte S, Keijer J, O'Brien K, Sowton A, Murray AJ, Campbell MD, Marcinek DJ, Nollet E, Wüst R, Dayanidhi S, Gnaiger E, Doerrier C, Garcia-Roves PM
Published in: MitoFit Preprint Archives, 2019

Commitment to reproducibility in targeting mitochondrial respiratory control: basic and advanced applications of the O2k-FluoRespirometer

Author(s): Doerrier C, Di Marcello M, Gnaiger E
Published in: 2020

Endogenous quinones sustain a moderate NADH oxidation by Complex I during anoxia

Author(s): Ravasz D, Bui D, Kitayev A, Greenwood B, Hill C, Komlodi T, Doerrier C, Ozohanics O, Moore AL, Gnaiger E, Kiebish M, Kolev K, Seyfried TN, Willis WT, Narain N, Adam-Vizi V, Chinopoulos C
Published in: 2019

Succinate dehydrogenase is a source of reactive oxygen species in plants and regulates development and stress responses

Author(s): Huete-Ortega M
Published in: O2k-brief, Issue 2019-06-05, 2019

Regulation of ATP production: dependence on calcium concentration and respiratory state

Author(s): Cardoso L
Published in: O2k-brief, Issue 2019-06-12, 2019

Mitochondrial respiration in peripheral blood mono nuclear cells correlates with depressive sub-symptoms and severity of major depression

Author(s): Garcia-Souza LF
Published in: O2k-brief, Issue 2019-06-19, 2019

Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart

Author(s): Gnaiger E and Iglesias-Gonzalez J
Published in: O2k-brief, Issue 2019-06-26, 2019

High intensity exercise inhibits carnitine palmoyltranferase-I sensitivity to L-carnitine

Author(s): Krumschnable G
Published in: O2k-brief, Issue 2019-07-02, 2019

Rapid kinetics of changes in oxygen consumption rate in thrombin-stimulated platelets measured by high-resolution respirometry

Author(s): Garcia-Souza LF
Published in: O2k-brief, Issue 2019-07-09, 2019

Direct effects of phenformin on metabolism/bioenergetics and viability of SH-SY5Y neuroblastoma cells

Author(s): Bastos AC
Published in: O2k-brief, 2019

Selective disruption of respiratory supercomplexes as a new strategy to supress Her2high breast cancer

Author(s): Bastos AC
Published in: O2k-brief, Issue 2019-07-24, 2019

Endogenous myoglobin in breast cancer is hypoxia-inducible by alternate transcription and functions to impair mitochondrial activity: a role in tumor suppression?

Author(s): Iglesias-Gonzalez J
Published in: O2k-brief, Issue 2019-07-31, 2019

6-Hydroxidopamine induces different mitochondrial bioenergetics response in brain regions of rat

Author(s): Iglesias-Gonzalez J
Published in: O2k-brief, Issue 2019-08-07, 2019

Non-canonical BAD activity regulates breast cancer cells and tumor growth via 14-3-3 binding and mitochondrial metabolism

Author(s): Tindle-Solomon L
Published in: O2k-brief, Issue 2019-10-25, 2019

Measurement of ADP-ATP exchange in relation to mitochondrial transmembrane potential and oxygen consumption

Author(s): Tindle-Solomon L
Published in: O2k-brief, Issue 2019-11-28, 2019

Analysis of respiratory capacity in brain tissue preparations: high-resolution respirometry for intact hippocampal slices

Author(s): Tindle-Solomon L
Published in: O2k-brief, Issue 2019-11-12, 2019

Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis

Author(s): Antunes D and Tindle-Solomon L
Published in: O2k-brief, Issue 2020-01-20, 2020

The metabolite BH4 controls T cell proliferation in autoimmunity and cancer

Author(s): Garcia-Souza LF and Tindle-Solomon L
Published in: O2k-brief, Issue 2020-02-04, 2020

Effects of aging and exercise training on mitochondrial function and apoptosis in the rat heart

Author(s): Cecatto C and Tindle-Solomon L
Published in: O2k-brief, Issue 2020-03-18, 2020

Effect of initial aging and high-fat/high-fructose diet on mitochondrial bioenergetics and oxidative status in rat brain

Author(s): Antunes D and Tindle-Solomon L
Published in: O2k-brief, Issue 2020-03-05, 2020

Muscle-derived GDF15 drives diurnal anorexia and systemic metabolic remodeling during mitochondrial stress

Author(s): Antunes D and Tindle-Solomon L
Published in: O2k-brief, Issue 2020-04-03, 2020

Respiratory chain signaling is essential for adaptive remodeling following cardiac ischaemia

Author(s): Komlodi T and Tindle-Solomon L
Published in: O2k-brief, Issue 2020-05-15, 2020

OXPHOS remodeling n high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation

Author(s): Bastos AC and Tindle-Solomon L
Published in: O2k-brief, Issue 2020-05-28, 2020

Peripheral mitochondrial dysfunction in Alzheimer’s disease: focus on lymphocytes.

Author(s): Garcia-Souza LF and Tindle-Solomon L
Published in: O2k-brief, Issue 2020-04-16, 2020