Descripción del proyecto
Prevención y tratamiento avanzados y personalizados de aneurismas
Los aneurismas son potencialmente mortales y pueden provocar la muerte en cuestión de minutos. El equipo del proyecto MeDiTATe, financiado con fondos europeos, desarrollará gemelos digitales médicos avanzados a partir de imágenes de regiones cardiovasculares para la prevención y el tratamiento personalizados de aneurismas. El proyecto formará a catorce investigadores noveles en simulación multifísica de ingeniería asistida por ordenador (IAO) de alta fidelidad con transformación de malla a partir de funciones de base radial; interacción en tiempo real con los gemelos digitales mediante realidad aumentada; dispositivos hápticos y modelos de orden reducido; herramientas de informática de alto rendimiento, incluidas las unidades de procesamiento gráfico, y paradigmas basados en la nube para el procesamiento por IAO rápido y automatizado de la base de datos clínica; gestión de datos masivos para el conjunto de datos de imágenes de pacientes y gemelos de IAO de alta fidelidad; y fabricación por adición de réplicas físicas para la planificación y la formación quirúrgicas.
Objetivo
MeDiTATe aims to develop state-of-the-art image based medical Digital Twins of cardiovascular districts for a patient specific prevention and treatment of aneurysms. The Individual Research Projects of the 14 ESRs are defined across five research tracks:
(1) High fidelity CAE multi-physics simulation with RBF mesh morphing (FEM, CFD, FSI, inverse FEM)
(2) Real time interaction with the digital twin by Augmented Reality, Haptic Devices and Reduced Order Models
(3) HPC tools, including GPUs, and cloud-based paradigms for fast and automated CAE processing of clinical database
(4) Big Data management for population of patients imaging data and high fidelity CAE twins
(5) Additive Manufacturing of physical mock-up for surgical planning and training to gain a comprehensive Industry 4.0 approach in a clinical scenario (Medicine 4.0)
The work of ESRs, each one hired for two 18 months periods (industry + research) and enrolled in PhD programmes, will be driven by the multi disciplinary and multi-sectoral needs of the research consortium (clinical, academic and industrial) which will offer the expertise of Participants to provide scientific support, secondments and training. Recruited researchers will become active players of a strategic sector of the European medical and simulation industry and will face the industrial and research challenges daily faced by clinical experts, engineering analysts and simulation software technology developers. During their postgraduate studies they will be trained by the whole consortium receiving a flexible and competitive skill-set designed to address a career at the cutting edge of technological innovation in healthcare. The main objective of MeDiTATe is the production of high-level scientists with a strong experience of integration across academic, industrial and clinical areas, able to apply their skills to real life scenarios and capable to introduce advanced and innovative digital twin concepts in the clinic and healthcare sectors.
Ámbito científico
- natural sciencescomputer and information sciencesdatabases
- medical and health sciencesclinical medicineangiologyvascular diseases
- natural sciencescomputer and information sciencesdata sciencebig data
- engineering and technologymechanical engineeringmanufacturing engineeringadditive manufacturing
- natural sciencescomputer and information sciencessoftwaresoftware applicationssimulation software
Palabras clave
Programa(s)
Régimen de financiación
MSCA-ITN - Marie Skłodowska-Curie Innovative Training Networks (ITN)Coordinador
00133 Roma
Italia