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Innovative strategies for cancer prevention with focus on sex hormone signaling and chronic inflammation

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Publications

Loss of keratinocyte Mcpip1 abruptly activates the IL-23/Th17 and Stat3 pathways in skin inflammation

Author(s): Agata Lichawska-Cieslar, Piotr Konieczny, Weronika Szukala, Wim Declercq, Mingui Fu, Jolanta Jura
Published in: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Issue 1868/1, 2021, Page(s) 118866, ISSN 0167-4889
DOI: 10.1016/j.bbamcr.2020.118866

Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection

Author(s): Tania Løve Aaes, Hanne Verschuere, Agnieszka Kaczmarek, Liesbeth Heyndrickx, Bartosz Wiernicki, Iris Delrue, Bram De Craene, Joachim Taminau, Tinneke Delvaeye, Mathieu J. M. Bertrand, Wim Declercq, Geert Berx, Dmitri V. Krysko, Sandy Adjemian, Peter Vandenabeele
Published in: The Journal of Immunology, Issue 204/4, 2020, Page(s) 775-787, ISSN 0022-1767
DOI: 10.4049/jimmunol.1900072

Inhibitors Targeting RIPK1/RIPK3: Old and New Drugs

Author(s): Sofie Martens, Sam Hofmans, Wim Declercq, Koen Augustyns, Peter Vandenabeele
Published in: Trends in Pharmacological Sciences, Issue 41/3, 2020, Page(s) 209-224, ISSN 0165-6147
DOI: 10.1016/j.tips.2020.01.002

Epithelial HMGB1 Delays Skin Wound Healing and Drives Tumor Initiation by Priming Neutrophils for NET Formation

Author(s): Esther Hoste, Christian Maueröder, Lisette van Hove, Leen Catrysse, Hanna-Kaisa Vikkula, Mozes Sze, Bastiaan Maes, Dyah Karjosukarso, Liesbet Martens, Amanda Gonçalves, Eef Parthoens, Ria Roelandt, Wim Declercq, Ignacia Fuentes, Francis Palisson, Sergio Gonzalez, Julio C. Salas-Alanis, Louis Boon, Peter Huebener, Klaas Willem Mulder, Kodi Ravichandran, Yvan Saeys, Robert Felix Schwabe, Geert van
Published in: Cell Reports, Issue 29/9, 2019, Page(s) 2689-2701.e4, ISSN 2211-1247
DOI: 10.1016/j.celrep.2019.10.104

Keratinocyte-specific ablation of Mcpip1 impairs skin integrity and promotes local and systemic inflammation

Author(s): Piotr Konieczny, Agata Lichawska-Cieslar, Patrycja Kwiecinska, Joanna Cichy, Roza Pietrzycka, Weronika Szukala, Wim Declercq, Michael Devos, Agnieszka Paziewska, Izabela Rumienczyk, Maria Kulecka, Michal Mikula, Mingui Fu, Julia Borowczyk, Luis F Santamaria-Babí, Jolanta Jura
Published in: Journal of Molecular Medicine, Issue 97/12, 2019, Page(s) 1669-1684, ISSN 0946-2716
DOI: 10.1007/s00109-019-01853-2

Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation

Author(s): Michael Devos, Giel Tanghe, Barbara Gilbert, Evelien Dierick, Maud Verheirstraeten, Josephine Nemegeer, Richard de Reuver, Sylvie Lefebvre, Jolien De Munck, Jan Rehwinkel, Peter Vandenabeele, Wim Declercq, Jonathan Maelfait
Published in: Journal of Experimental Medicine, Issue 217/7, 2020, ISSN 0022-1007
DOI: 10.1084/jem.20191913

Wnt signaling and Loxl2 promote aggressive osteosarcoma

Author(s): Kazuhiko Matsuoka, Latifa Bakiri, Lena I. Wolff, Markus Linder, Amanda Mikels-Vigdal, Ana Patiño-García, Fernando Lecanda, Christine Hartmann, Maria Sibilia, Erwin F. Wagner
Published in: Cell Research, Issue 30/10, 2020, Page(s) 885-901, ISSN 1001-0602
DOI: 10.1038/s41422-020-0370-1