Skip to main content
Go to the home page of the European Commission (opens in new window)
English English
CORDIS - EU research results
CORDIS

Innovative strategies for cancer prevention with focus on sex hormone signaling and chronic inflammation

Project description

A novel training network hopes to elucidate new strategies for prevention of common cancers

Two important factors affecting risk of cancer development are chronic inflammation and levels of circulating sex hormones. More than 150 years ago, scientists observed that inflammatory cells are present within tumours and that tumours arise at sites of chronic inflammation, resulting in a purported link between the two. Years of epidemiological studies now suggest that up to a fourth of cancers are due to chronic infection or other types of chronic inflammation. In addition, there is now a strong correlation between levels of circulating sex hormones and female reproductive cancers. The CANCERPREV project is training young researchers in cutting edge mathematical and experimental techniques to develop new guidelines for the prevention of cancers associated with reproductive and non-reproductive organs.

Objective

Incidence and prevalence of many cancer types are significantly increasing worldwide, with substantial differences between the sexes. Environmental influences in concert with genetic and epigenetic factors are still poorly understood.
Simultaneously, more sophisticated and expensive treatments cannot be afforded by society, increasing urgency of efforts in cancer prevention.
CANCERPREV is an innovative interdisciplinary research and training program gathering seven academic beneficiaries and nine partner organizations : (one leading pharmaceutical company, one leading technology company, a health insurance, an internationally known nursing school, three foundations and two universities) in nine European countries. CANCERPREV aims to establish new strategies in cancer prevention, with a focus on two key determinants of cancer risk: sex hormone signaling and chronic inflammation, in breast and skin as benchmarks of early steps of cancer development in organs with reproductive and non-reproductive functions, respectively.
Fifteen Early Stage Researchers (ESRs) will benefit from the complementary expertise of participating organizations and Principal Investigators in: basic cancer research, xenografts and genetic mouse models, bioinformatics and mathematical algorithms, epidemiology / human genetics, biomarkers, pharmacological approaches, behavioral / societal issues and outreach.
This network provides ESRs with unique future career opportunities in both academic and private sectors, through research training for PhD thesis projects with secondments and short and long visits to other participating research institutions, and yearly courses / formal lectures on various aspects of cancer prevention, including global health and occupational / behavioral issues. CANCERPREV will ensure that more knowledge and ideas are converted into products and services, and that a new generation of scientists is trained to contribute to the knowledge-based economy and society.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

You need to log in or register to use this function

Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-ITN - Marie Skłodowska-Curie Innovative Training Networks (ITN)

See all projects funded under this funding scheme

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-ITN-2019

See all projects funded under this call

Coordinator

ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 843 829,92
Address
BATIMENT CE 3316 STATION 1
1015 Lausanne
Switzerland

See on map

Region
Schweiz/Suisse/Svizzera Région lémanique Vaud
Activity type
Higher or Secondary Education Establishments
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 843 829,92

Participants (6)

My booklet 0 0