Photonics for Healthcare: multiscAle cancer diagnosiS and Therapy

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PHAST project website and visual identity

PHAST project website completed and visual identity defined

Pubblicazioni

Preliminary Evidence of the Efficacy of Time-Resolved Broad-Spectrum Optical Mammography in Monitoring Neoadjuvant Chemotherapy

Autori: Giulia Maffeis, Nikhitha Mule, Carolina Santangelo, Rinaldo Cubeddu, Antonio Pifferi, Pietro Panizza, and Paola Taroni
Pubblicato in: Biophotonics Congress: Biomedical Optics 2022 (Translational, Microscopy, OCT, OTS, BRAIN), 2022, ISBN 978-1-957171-03-6
Editore: Optica Publishing Group
DOI: 10.1364/translational.2022.jm3a.28

Modified optical fiber sensors for intravital monitoring

Autori: Malhar Nagar, Marco Lai, Davide Janner
Pubblicato in: Translational Biophotonics: Diagnostics and Therapeutics III, 2024, Pagina/e 100
Editore: SPIE
DOI: 10.1117/12.2669431

Resorbable optical fibers for monitoring physiological signals: a proof-of-concept validation

Autori: Jawad Talekkara Pandayil, Nadia G. Boetti, Lorenzo Cortese, Davide Janner, Turgut Durduran
Pubblicato in: Biomedical Spectroscopy, Microscopy, and Imaging III, 2024, Pagina/e 99
Editore: SPIE
DOI: 10.1117/12.3022144

Rigid endomicroscopic system for cancer diagnosis and tissue removal

Autori: Matteo Calvarese, Hyeonsoo Bae, Chenting Lai, Karl Reichwald, Tobias Meyer-Zedler, Bernhard Messerschmidt, Ayman Bali, David Pertzborn, Anna Mühlig, Orlando Guntinas-Lichius, Michael Schmitt, Juergen Popp
Pubblicato in: Proceedings Volume PC12839, Biomedical Vibrational Spectroscopy 2024: Advances in Research and Industry, 2024
Editore: PC1283906 (2024) SPIE BiOS, 2024, San Francisco, California, United States
DOI: 10.1117/12.3009975

Point-of-care Raman microspectroscopy for detecting head and neck tumour markers in body liquids

Autori: Edoardo Farnesi, Chen Liu, Dana Cialla-May, Michael Schmitt, Orlando Guntinas-Lichius, Juergen Popp
Pubblicato in: Numero ANAKON 2023 April 11-14, 2023, 2023
Editore: ANAKON 2023

Multiphoton imaging in conjunction with ICG imaging by a rigid endomicroscope combined with laser ablation in the head and neck region

Autori: Chenting Lai, Bernhard Messerschmidt, Karl Reichwald, Sven Flämig, Tino Eidam, Fabian Stutzki, Matteo Calvarese, Hyeonsoo Bae, Tobias Meyer-Zedler, Michael Schmitt, Herbert Gross, Franziska Hoffmann, Orlando Guntinas-Lichius, Juergen Popp
Pubblicato in: Proc. SPIE 12384, Multiphoton Microscopy in the Biomedical Sciences XXIII; 123840G (25 April 2023), Numero Proc. SPIE 12384, Multiphoton Microscopy in the Biomedical Sciences XXIII; 123840G (25 April 2023), 2023
Editore: SPIE
DOI: 10.1117/12.2650213

Spectral tissue imaging for exvivo cancer diagnosis and survey

Autori: Pooja GIRISH, Sébastien LEGENDRE , Olivier PIOT
Pubblicato in: Women in Photonics, Numero 2022, 2022
Editore: Women in Photonics,2022

Rigid endomicroscopic system for multiphoton imaging and tissue ablation in the head and neck region

Autori: Chenting Lai, Bernhard Messerschmidt, Karl Reichwald, Sven Flämig, Tino Eidam, Fabian Stutzki, Matteo Calvarese, Hyeonsoo Bae, Tobias Meyer-Zedler, Michael Schmitt, Herbert Gross, Franziska Hoffmann, Orlando Guntinas-Lichius, Juergen Popp
Pubblicato in: Proc. SPIE 12356, Endoscopic Microscopy XVIII; 1235609 (14 March 2023), Numero Proc. SPIE 12356, Endoscopic Microscopy XVIII; 1235609 (14 March 2023), 2023
Editore: SPIE
DOI: 10.1117/12.2650081

Raman microspectroscopy for detecting head and neck tumour markers in body liquids

Autori: Edoardo Farnesi, Chen Liu, Michael Schmitt, Dana Cialla-May, Juergen Popp
Pubblicato in: ICOB 2024, 2024
Editore: ICOB 2024

Optical comb interrogation of structured FBGs for physiological pressure sensing

Autori: Malhar A. Nagar, Minghao Wei, Prince Anandarajah, Aleksandra Kaszubowska-Anandarajah, Nadia G. Boetti, Davide Janner
Pubblicato in: Photonics West 2025, 2025
Editore: SPIE

Study of lipid involvement in breast cancer by using vibrational imaging on tissue samples from normal and obese patients

Autori: Pooja Mol Girish, Sébastien Legendre, Catherine Muller, Charlotte Vaysse, Emilie Buach, Nicolas Goffin, Olivier Piot
Pubblicato in: Translational Biophotonics: Diagnostics and Therapeutics III, Numero Proc. SPIE 12627, 2023, Pagina/e 1262734
Editore: SPIE
DOI: 10.1117/12.2670677

Tandem SERS and MD profiling of salivary biomarkers for point-of-care sensors detecting head and neck cancer and infections

Autori: Edoardo Farnesi, Chen Liu, Michael Schmitt, Dana Cialla-May, Juergen Popp
Pubblicato in: ICORS 2024, 2024
Editore: ICORS 2024

Real-time FBG wavelength shift sensing system using a gain switched dual comb

Autori: Minghao Wei, Conor McArdle, Aleksandra Kaszubowska-Anandarajah, Alejandro Rosado, Davide Janner, Malhar Nagar, Prince M. Anandarajah
Pubblicato in: OFC 2025, 2025
Editore: Optica

Rigid endomicroscopic system for cancer diagnosis and tissue removal

Autori: Matteo Calvarese, Chenting Lai, Hyeonsoo Bae, Karl Reichwald, Tobias Meyer-Zedler, Bernhard Messerschmidt, Orlando Guntinas-Lichius, Micheal Schmitt, Juergen Popp
Pubblicato in: Numero ANAKON 2023 April 11-14, 2023, 2023
Editore: ANAKON 2023

Optical fiber pressure sensing for biomedical applications using frequency selective technique

Autori: Malhar Nagar, Marco Lai, Davide Janner
Pubblicato in: European Workshop on Optical Fibre Sensors (EWOFS 2023), 2023, Pagina/e 88
Editore: SPIE
DOI: 10.1117/12.2678994

Miniaturized CARS endomicroscopic probe with a large field of view using a MEMS mirror scanner: concept and design considerations

Autori: Chenting Lai, Aida Amantayeva, Karl Reichwald, Sandra Gerlach-Anhut, Tobias Meyer-Zedler, Adrian Lorenz, Jörg Bierlich, Tobias Habisreuther, Bernhard Messerschmidt
Pubblicato in: Endoscopic Microscopy XIX, Numero 7, 2024, Pagina/e 12
Editore: SPIE
DOI: 10.1117/12.3003833

Analysis of salivary biomarkers for point-of-care sensors detecting head and neck cancer and infections by SERS/MD approach

Autori: Edoardo Farnesi, Silvia Rinaldi, Chen Liu, Jonas Ballmaier, Orlando Guntinas-Lichius, Michael Schmitt, Dana Cialla-May, Juergen Popp
Pubblicato in: Optica Biophotonics Congress: Biomedical Optics 2024 (Translational, Microscopy, OCT, OTS, BRAIN), 2024, Pagina/e OW1D.1
Editore: Optica Publishing Group
DOI: 10.1364/ots.2024.ow1d.1

Towards a novel bi-functional bioresorbable micro-structured optical fiber for theranostic applications

Autori: Jawad Talekkara Pandayil, Seyed Hossein Mussavi Rizi, Sharon Russo, Nadia Giovanna Boetti, Diego Pugliese, Davide Janner
Pubblicato in: Translational Biophotonics: Diagnostics and Therapeutics III, 2024, Pagina/e 56
Editore: SPIE
DOI: 10.1117/12.2670867

Study of lipid involvement in breast cancer by using vibrational imaging on tissue samples from normal and obese patient

Autori: P. Girish, S. Legendre , C. Muller , C. Vaysse , E. Buache , N. Goffin , O. Piot
Pubblicato in: FOM 2023, Numero 2023, 2023
Editore: FOM

Bioresorbable multifunctional fiber-optic devices for theranostic and monitoring of tumor

Autori: Jawad Pandayil, Nadia Giovanna Boetti, Diego Pugliese, Lorenzo Cortese, Sai Vamshi Krishna Damagatla, Turgut Durduran, Antonio Pifferi, Davide Janner
Pubblicato in: Optical Fibers and Sensors for Medical Diagnostics, Treatment, and Environmental Applications XXIV, 2024, Pagina/e 4
Editore: SPIE
DOI: 10.1117/12.3002672

Point-of-care Raman microspectroscopy for detecting Head and Neck tumours markers in body liquids

Autori: Edoardo Farnesi, Dana Cialla-May, Juergen Popp and Michael Schmitt
Pubblicato in: Numero 5th MUNICH POCT SYMPOSIUM (September 27–29, 2022), 2022
Editore: 5th MUNICH POCT SYMPOSIUM

Advancements in Biomedical Applications of Calcium Phosphate Glass and Glass-Based Devices—A Review

Autori: Jawad Pandayil, Nadia Boetti, Davide Janner
Pubblicato in: Journal of Functional Biomaterials, Numero 15, 2024, Pagina/e 79, ISSN 2079-4983
Editore: MDPI (Multidisciplinary Digital Publishing Institute)
DOI: 10.3390/jfb15030079

Two-layer reconstruction of Raman spectra in diffusive media based on analytical model in the time domain

Autori: Stefan Susnjar, Fabrizio Martelli, Sara Mosca, Sanathana Konugolu Venkata Sekar, Jjohannes Swartling, Nina Reistad, Andrea Farina, Antonio Pifferi
Pubblicato in: Optics Express, 2023, ISSN 1094-4087
Editore: Optical Society of America
DOI: 10.1364/opticaopen.24138657

Polymer-Based Optical Guided-Wave Biomedical Sensing: From Principles to Applications

Autori: Malhar A. Nagar, Davide Janner
Pubblicato in: Photonics, Numero 11, 2024, Pagina/e 972, ISSN 2304-6732
Editore: MDPI
DOI: 10.3390/photonics11100972

Estimation of biological variance in coherent Raman microscopy data of two cell lines using chemometrics

Autori: Rajendhar Junjuri, Matteo Calvarese, MohammadSadegh Vafaeinezhad, Federico Vernuccio, Marco Ventura, Tobias Meyer-Zedler, Benedetta Gavazzoni, Dario Polli, Renzo Vanna, Italia Bongarzone, Silvia Ghislanzoni, Matteo Negro, Juergen Popp, Thomas Bocklitz
Pubblicato in: The Analyst, Numero 149, 2024, Pagina/e 4395-4406, ISSN 0003-2654
Editore: Royal Society of Chemistry
DOI: 10.1039/d4an00648h

3D Nano‐Printed Bistable Microlens Actuator for Reconfigurable Micro‐Optical Systems

Autori: Aybuke Calikoglu, Florian Lux, Yanis Taege, Hans Zappe, Çağlar Ataman
Pubblicato in: Advanced Functional Materials, 2024, ISSN 1616-301X
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202408867

Enhanced medical diagnosis for dOCTors: a perspective of optical coherence tomography

Autori: Rainer A. Leitgeb, Fabian Placzek, Elisabet A. Rank, Lisa Krainz, Richard Haindl, Qian Li, Mengyang Liu, Mengyang Liu, Angelika Unterhuber, Tilman Schmoll, Wolfgang Drexler
Pubblicato in: Journal of Biomedical Optics, Numero 10833668, 2021, Pagina/e 100601, ISSN 1083-3668
Editore: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.26.10.100601

3D nanoprinted catadioptric fiber sensor for dual-axis distance measurement during vitrectomy

Autori: Florian Lux, Aybuke Calikoglu, Carolin Klusmann, Matthias Hillenbrand, Çağlar Ataman
Pubblicato in: Applied Optics, Numero 63, 2024, Pagina/e 2806, ISSN 1559-128X
Editore: Optica
DOI: 10.1364/ao.518950

Assessment of Microvascular Hemodynamic Adaptations in Finger Flexors of Climbers

Autori: Blai Ferrer-Uris, Albert Busquets, Faruk Beslija and Turgut Durduran
Pubblicato in: Bioengineering, Numero 11,4, 2024, Pagina/e 401, ISSN 2306-5354
Editore: MDPI
DOI: 10.3390/bioengineering11040401

Magnetic position sensing for self-calibration and image registration of scanning fiber endoscopes

Autori: Aybüke Çalıkoğlu, Gerardo González-Cerdas, David Ilioae, Marius Kienzler, Florian Lux, Yanis Taege, Çağlar Ataman
Pubblicato in: Journal of Optical Microsystems, Numero 4, 2024, ISSN 2708-5260
Editore: Society of Photo-Optical Instrumentation Engineers
DOI: 10.1117/1.jom.4.1.014003

Endomicroscopic AI-driven morphochemical imaging and fs-laser ablation for selective tumor identification and selective tissue removal

Autori: Matteo Calvarese, Elena Corbetta, Jhonatan Contreras, Hyeonsoo Bae, Chenting Lai, Karl Reichwald, Tobias Meyer-Zedler, David Pertzborn, Anna Mühlig, Franziska Hoffmann, Bernhard Messerschmidt, Orlando Guntinas-Lichius, Michael Schmitt, Thomas Bocklitz, Juergen Popp
Pubblicato in: Science Advances, Numero 10, 2024, Pagina/e Vol. 10(50), ISSN 2375-2548
Editore: Science Advance
DOI: 10.1126/sciadv.ado9721

Recent developments and advances of femtosecond laser ablation: Towards image-guided microsurgery probes

Autori: Matteo Calvarese a, Tobias Meyer-Zedler a, Michael Schmitt b, Orlando Guntinas-Lichius c, Jürgen Popp
Pubblicato in: Trends in Analytical Chemistry 167 (2023) 117250, Numero 167 (2023) 117250, 2023, ISSN 0165-9936
Editore: Elsevier BV
DOI: 10.1016/j.trac.2023.117250

Recent advances of surface enhanced Raman spectroscopy (SERS) in optical biosensing

Autori: Dana Cialla-May, Alois Bonifacio, Alexey Markin, Natalia Markina, Stefano Fornasaro, Aradhana Dwivedi, Tony Dib, Edoardo Farnesi, Chen Liu, Arna Ghosh, Michael Schmitt, Juergen Popp
Pubblicato in: TrAC Trends in Analytical Chemistry, Numero 181, 2024, Pagina/e 117990, ISSN 0165-9936
Editore: Elsevier BV
DOI: 10.1016/j.trac.2024.117990

A comprehensive workflow and its validation for simulating diffuse speckle statistics for optical blood flow measurements

Autori: Lisa Kobayashi Frisk; Manish Verma; Faruk Bešlija; Chen-Hao P. Lin; Nishighanda Patil; Sumana Chetia; Jason W. Trobaugh; Joseph P. Culver; Turgut Durduran
Pubblicato in: bioRxiv, Numero 12, 2024, Pagina/e 875-899, ISSN 2156-7085
Editore: The Optical Society
DOI: 10.1101/2023.08.03.551830

Proof of concept validation of bioresorbable optical fibers for diffuse correlation spectroscopy

Autori: Jawad T. Pandayil, Nadia G. Boetti, Davide Janner, Turgut Durduran, Lorenzo Cortese
Pubblicato in: Biomedical Optics Express, Numero 15, 2024, Pagina/e 6384, ISSN 2156-7085
Editore: The Optical Society
DOI: 10.1364/boe.540137

Potential role of Er:YAG laser and fluoride in the dental enamel remineralization: a Raman spectroscopy preliminary ex-vivo study

Autori: Aizhan Issatayeva, Carlo Fornaini, Matteo Masino, Annamaria Cucinotta
Pubblicato in: Laser Therapy, Numero 18847269, 2022, Pagina/e 5-12, ISSN 1884-7269
Editore: Filodritto Publisher
DOI: 10.26352/gj06f5001-june2022

Monitoring of neoadjuvant chemotherapy through time domain diffuse optics: breast tissue composition changes and collagen discriminative potential

Autori: Nikhitha Mule, Giulia Maffeis, Rinaldo Cubeddu, Carolina Santangelo, Giampaolo Bianchini, Pietro Panizza, Paola Taroni
Pubblicato in: Biomedical Optics Express, Numero 15, 2024, Pagina/e 4842, ISSN 2156-7085
Editore: The Optical Society
DOI: 10.1364/boe.527968

Towards enhanced cancer therapy; Leveraging bioresorbable optical fibers for improved treatment outcomes

Autori: Jawad T. Pandayil, Stefan Šušnjar, Lorenzo Cortese, Nadia G. Boetti, Johannes Swartling, Davide Janner, Turgut Durduran
Pubblicato in: EPJ Web of Conferences, Numero 309, 2024, Pagina/e 04025, ISSN 2100-014X
Editore: EDP
DOI: 10.1051/epjconf/202430904025

Hybrid Heterogeneous Phantoms for Biomedical Applications: a demonstration to dosimetry validation

Autori: Muhammad Daniyal Ghauri, Stefan Susnjar, Claudia Guadagno, Somdatta Bhattacharya, Björn Thomasson, Jjohannes Swartling, Rekha Gautam, Stefan Andersson Engels, Sanathana Konugolu Venkata Sekar
Pubblicato in: Journal Biomedical Optics Express, Numero Vol. 15, Numero 2,(2024), 2024, Pagina/e pp. 863-874, ISSN 2156-7085
Editore: The Optical Society
DOI: 10.1364/opticaopen.24713385.v1

In vivo optimization of the experimental conditions for the non-invasive optical assessment of breast density

Autori: Nicola Serra, Rinaldo Cubeddu, Giulia Maffeis, Vamshi Damagatla, Antonio Pifferi, Paola Taroni
Pubblicato in: Scientific Reports, Numero 14, 2024, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-024-70099-x

Advancing cerumen analysis: exploring innovative vibrational spectroscopy techniques with respect to their potential as new point-of-care diagnostic tools

Autori: Edoardo Farnesi, Matteo Calvarese, Chen Liu, Carl Messerschmidt, MohammadSadegh Vafaeinezhad, Tobias Meyer-Zedler, Dana Cialla-May, Christoph Krafft, Jonas Ballmaier, Orlando Guntinas-Lichius, Michael Schmitt, Jürgen Popp
Pubblicato in: The Analyst, Numero 149, 2024, Pagina/e 5381-5393, ISSN 0003-2654
Editore: Royal Society of Chemistry
DOI: 10.1039/d4an00868e

Elastomeric-coated FBGs for point-of-care diagnostics

Autori: Malhar A. Nagar, Giovanni Mingoia, Davide Janner
Pubblicato in: EPJ Web of Conferences, Numero 309, 2024, Pagina/e 04007, ISSN 2100-014X
Editore: EDP Science
DOI: 10.1051/epjconf/202430904007

Biomedical SERS – the current state and future trends

Autori: Dana Cialla-May, Alois Bonifacio, Thomas Bocklitz, Alexey Markin, Natalia Markina, Stefano Fornasaro, Aradhana Dwivedi, Tony Dib, Edoardo Farnesi, Chen Liu, Arna Ghosh, Juergen Popp
Pubblicato in: Chemical Society Reviews, Numero 53, 2024, Pagina/e 8957-8979, ISSN 0306-0012
Editore: Royal Society of Chemistry
DOI: 10.1039/d4cs00090k

Label-Free SERS and MD Analysis of Biomarkers for Rapid Point-of-Care Sensors Detecting Head and Neck Cancer and Infections

Autori: Edoardo Farnesi 1,2 , Silvia Rinaldi 3 , Chen Liu 1,2, Jonas Ballmaier 4 , Orlando Guntinas-Lichius 4 , Michael Schmitt 1 , Dana Cialla-May 1,2,* and Juergen Popp 1,2
Pubblicato in: MDPI sensors, Numero 2023, 23, 8915, 2023, ISSN 1424-8220
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s23218915

Relationship between overall right pre-frontal cortex activity and learning and retention of a visuomotor adaptation task: a continuous analysis

Autori: M.Á. Ramos, A. Busquets, B. Ferrer-Uris, A. Eken, F. Beslija, F. Zhang, T. Durduran, R. Angulo-Barroso
Pubblicato in: Psychology of Sport and Exercise, 2025, Pagina/e 102827, ISSN 1469-0292
Editore: Elsevier BV
DOI: 10.1016/j.psychsport.2025.102827

Use of bioresorbable fibers for short-wave infrared spectroscopy using time-domain diffuse optics

Autori: Vamshi Damagatla, Nadia G. Boetti, Laura Di Sieno, Ilaria Bargigia, Fabio Negretti, Diego Pugliese, Davide Janner, Lorenzo Spinelli, Andrea Farina, Antonio Pifferi
Pubblicato in: Biomedical Optics Express, Numero 15, 2024, Pagina/e 5041, ISSN 2156-7085
Editore: The Optical Society
DOI: 10.1364/boe.531681

Design and test of a rigid endomicroscopic system for multimodal imaging and femtosecond laser ablation

Autori: Chenting Lai, Matteo Calvarese, Karl Reichwald,a Hyeonsoo Bae, Mohammadsadegh Vafaeinezhad, Tobias Meyer-Zedler, Franziska Hoffmann, Anna Mühlig, Tino Eidam,Fabian Stutzki, Bernhard Messerschmidt ,Herbert Gross, Michael Schmitt, Orlando Guntinas-Lichius and Jürgen Popp
Pubblicato in: Journal of Biomedical Optics, Numero Vol. 28(6), 2023, ISSN 1083-3668
Editore: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.28.6.066004

Interstitial null-distance time-domain diffuse optical spectroscopy using a superconducting nanowire detector

Autori: Vamshi Damagatla, Pranav Lanka, Annalisa Brodu, Niels Noordzij, Jessie Qin-Dregely, Andrea Farina, Antonio Pifferi
Pubblicato in: Journal of Biomedical Optics, Numero 28, 2024, ISSN 1083-3668
Editore: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.28.12.121202

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