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ONCOgenic Receptor Network of Excellence and Training 2.0

Project description

The encore to a successful training network is honing in on new targets for cancer therapies

Proteins are ubiquitous but they are not all created equal. G-protein-coupled receptors (GPCRs) are the largest and most diverse proteins in the mammalian genome. They are a class of transmembrane proteins that transduce extracellular stimuli or messengers into intracellular signals through interaction of their intracellular domains with G-proteins. The chemokine receptors CXCR4 and ACKR3 are GPCRs that bind the chemokine CXCL12 and they have been implicated in cancer, inflammatory and autoimmune diseases. They are a major target of numerous drug discovery efforts yet their exact mechanisms and roles remain unclear. The ONCORENET2.0 initiative plans to find out more and target new therapies with the help of 15 early stage researchers and recent pioneering work in the field of GPCRs.

Coordinator

STICHTING VU
Net EU contribution
€ 1 062 479,52
Address
De Boelelaan 1105
1081 HV Amsterdam
Netherlands
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Participants (9)

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France
Net EU contribution
€ 549 604,08
Address
Rue Michel Ange 3
75794 Paris
Activity type
Research Organisations
Non-EU contribution
€ 0,00
MAX DELBRUECK CENTRUM FUER MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (MDC)
Germany
Net EU contribution
€ 252 788,40
Address
Robert Rossle Strasse 10
13125 Berlin
Activity type
Research Organisations
Non-EU contribution
€ 0,00
UNIVERSITATSKLINIKUM JENA
Germany
Net EU contribution
€ 252 788,40
Address
Kastanienstr.1
07747 Jena
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
THE UNIVERSITY OF NOTTINGHAM
United Kingdom
Net EU contribution
€ 606 345,12
Address
University Park
NG7 2RD Nottingham
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Region
East Midlands (England) Derbyshire and Nottinghamshire Nottingham
UNIVERSIDAD AUTONOMA DE MADRID
Spain
Net EU contribution
€ 250 904,88
Address
Calle Einstein 3 Ciudad Univ Cantoblanco Rectorado
28049 Madrid
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Region
Comunidad de Madrid Comunidad de Madrid Madrid
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Net EU contribution
€ 274 802,04
Address
Rue De Tolbiac 101
75654 Paris
Activity type
Research Organisations
Non-EU contribution
€ 0,00
UNIVERSITY OF GLASGOW
United Kingdom
Net EU contribution
€ 303 172,56
Address
University Avenue
G12 8QQ Glasgow
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
QVQ HOLDING BV
Netherlands
Net EU contribution
€ 265 619,88
SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Address
Yalelaan 1 Kamer 0270
3584 CL Utrecht
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Region
West-Nederland Utrecht Utrecht
 
INTERAX BIOTECH AG
Switzerland
Net EU contribution
€ 281 276,64
SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Address
Park Innovaare
5234 Villingen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00