advanced technologieS for drug dIscovery and precisioN mEdicine: in vitRo modellinG human physiology and diseAse

Development of an ex vivo liver perfusion model for research purposes

Autores: Alicia Ruppelt, Alba Pueyo Moliner, Marco Stijnen, Bart Spee, Marco Rasponi
Publicado en: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Edición 28-31/03/2023, 2023
Editor: The University of Manchester

GENERATION AND CHARACTERIZATION OF HUMAN IPSC-DERIVED CARDIAC ORGANOIDS FOR TRANSLATIONAL MEDICINE

Autores: Ece Ergir, Soraia Fernandes, Francesco Niro, Daniel Sousa, Jan Vrbsky, Stefania Pagliari, Doriana Debellis, Heinz Redl, Peter Ertl, Giancarlo Forte
Publicado en: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Edición 83767252566, 2022
Editor: Mary Ann Liebert Inc. publishers

A microfluidic model of human vascularized breast cancer metastasis to bone for the study ofimmune-cancer cell interactions

Autores: Simone Bersini, Martina Crippa, Giuseppe Talò, Anais Lamouline, Chiara Arrigoni, Matteo Moretti
Publicado en: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, 2023
Editor: Springer Spektrum

Patient specific cardiac model of dilated cardiomyopathy in a beating heart-on-chip

Autores: Ferran Lozano Juan, Soraia Fernandes, Francesco Niro, Roberta Visone, Giancarlo Forte, Marco Rasponi, Paola Occhetta
Publicado en: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, Edición 269, 2023
Editor: Springer Spektrum

Development and functional characterization of a microphysiological system for assessing in vitro drug toxicity and metabolism in the hepatobiliary environment

Autores: Elisa Cauli, Claudia Piutti, Marco Rasponi, Claudio Bernardi
Publicado en: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, Edición 37, 2023
Editor: Springer Spektrum

3D BIOPRINTED CONSTRUCTS TO GENERATE MATURE ORGANOIDS FROM IPSC-DERIVED RENAL PROGENITORS

Autores: Chiara Formica, Gabriele Addario, Lorenzo Moroni, Carlos Mota
Publicado en: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Edición 83767228888, 2022
Editor: Mary Ann Liebert Inc. publishers

Perfusion bioreactor as a perspective platform for rapid and personalised drug-testing on patientderived prostate cancer tissue

Autores: Andrea Mazzoleni, Manuele Giuseppe Muraro, Arnaud Scherberich, Helge Seifert, Cyrill Rentsch, Lukas Bubendorf, Clémentine Le Magnen, Ivan Martin
Publicado en: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Edición 28-31/03/2023, 2023
Editor: The University of Manchester

Perfusion-based 3D in vitro model to study the interaction between prostate cancer andendothelial cells in the bone metastatic niche

Autores: Andrea Mazzoleni, Mathéo Gwinner, Philip Michael Dettinger, Arnaud Scherberich, Clémentine Le Magnen, Ivan Martin, Manuele Giuseppe Muraro
Publicado en: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Edición 28-31/03/2023, 2023
Editor: The University of Manchester

uHeart: a beating heart-on-chip for culturing 3D cardiac microtissues and recording on-line cardiac electrophysiology

Autores: Ferran Lozano, Roberta Visone, Simona Marzorati, Enrico Pesenti, Paola Occhetta, Marco Rasponi
Publicado en: Alternatives to Laboratory Animals - Special Edición: JRC Summer School 2021, Edición Volume 49 Edición 6, November 2021, 2021
Editor: SAGE journals

Development of a patient-specific lab-on-chip model of dystrophin deficient cardiomyopathy

Autores: Maria Carlos Oliveira, Stefano Piazza, Aoife Gowran, Marco Rasponi
Publicado en: Alternatives to Laboratory Animals - Special Edición: JRC Summer School 2021, Edición Volume 49 Edición 6, November 2021, 2021
Editor: SAGE journals

Generation of a 3D patient-specific cardiac fibrosis model using iPSCs

Autores: Daniel Pereira-Sousa, Francesco Niro, Ece Ergir, Jorge Oliver de la Cruz, Stefania Pagliari, Soraia Fernandes, Marco Cassani, Giancarlo Forte
Publicado en: 8th Advanced Summer School Interrogations at the biointerface: Fibrosis from mechanisms to the clinic, Edición 21-22/6/2022, 2022
Editor: i3s

Development of a platform to generate thousands of 3D spheroids for bioprinted liver model fordrug efficacy and safety assessment

Autores: Hélia Barros Fernandes, Gabriele Addario, Filipa Castro Teixeira, Cristina Degrassi, Marco Rasponi, Carlos Domingues Mota
Publicado en: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Edición 28-31/03/2023, 2023
Editor: The University of Manchester

Production of a reusable micromolded microcavity insert to standardize spheroid generation for drug screening

Autores: H. Fernandes, V. Valeri, C. Degrassi, M. Rasponi, C. Mota
Publicado en: Biomedical Science and Engineering 2023, Edición volume 4: 209, 2023
Editor: PAGEPress publications

A MICRO-PRECISION ELECTRO ARRAY (ΜPEA) PLATFORM INTEGRATED WITHIN A MECHANICALLY ACTIVE HEART-ON-CHIP FOR MODELLING DILATED CARDIOMYOPATHY

Autores: Ferran Lozano-Juan, Roberta Visone, Giancarlo Forte, Paola Occhetta, Marco Rasponi
Publicado en: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Edición 94238124605, 2022
Editor: Mary Ann Liebert Inc. publishers

ENGINEERING AN EX-VIVO PERFUSION-BASED BIOREACTOR SYSTEM FOR DRUG-TESTING ON PATIENT-SPECIFIC CANCER SPECIMENS

Autores: Manuele Giuseppe Muraro, Andrea Mazzoleni, Evrim Ceren Kabak, Arnaud Scherberich, Ivan Martin
Publicado en: TERMIS 6th World Congress, Edición 15-19/11/2021, 2021
Editor: Termis

Perfusion-based bioreactor ex-vivo model of prostate cancer for personalized drug-testing

Autores: Andrea Mazzoleni
Publicado en: TERMIS 6th World Congress, Edición 15-19/11/2021, 2021
Editor: Termis

Investigating the Determinants of Breast Cancer Dormancy in Bone

Autores: Evrim Ceren Kabak, Sherlyn Foo, Manuele Muraro, Tiberius Preca, Arnaud Scherberich, Mohamed Bentires Alj, Ivan Martin
Publicado en: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Edición 28-31/03/2023, 2023
Editor: The University of Manchester

TOWARDS PHYSIOLOGICALLY RELEVANT BIOPRINTED KIDNEY IN VITRO MODELS

Autores: Gabriele Addario, Sonja Djudjaj, Peter Boor, Lorenzo Moroni, Carlos Mota
Publicado en: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Edición 62825432139, 2022
Editor: Mary Ann Liebert Inc. publishers

Efficacy of Sorafenib treatment in a 3D hepatic cancer model

Autores: H. Fernandes, V. Valeri, C. Degrassi, M. Rasponi, C. Mota
Publicado en: I CONVEGNO NAZIONALE DELLA SOCIETÀ ITALIANA ORGAN-ON-CHIP – SIOoC2023, Edición 04-05/05/2023, 2023
Editor: SIOoC

Design and preliminary characterization of a new liveron-chip model as a valuable additional tool for assessing in vitro drug toxicity and metabolism in a similar physiological environment

Autores: Elisa Cauli, Simona Marzorati, Marco Rasponi, Claudio Bernardi1
Publicado en: ALTEX Proceedings: Abstracts of the 1st Microphysiological Systems World Summit, New Orleans, 2022, 2022
Editor: Springer

Biomechanically Stimulated 3D Endothelial Gut-on-Chip Platform to Study Immune Interactions

Autores: Karol Kugiejko, Mattia Ballerini, Luigi Nezi, Marco Rasponi
Publicado en: EUROoCS Annual Meeting 2022, Edición 04-05/07/2022, 2022
Editor: Conference presentation

BIOMECHANICALLY STIMULATED 3D ENDOTHELIAL GUT-ON-CHIP PLATFORM TO STUDY INTESTINE MICROBIOME AND IMMUNE SYSTEM INTERACTIONS

Autores: Karol Kugiejko, Mattia Ballerini, Luigi Nezi, Marco Rasponi
Publicado en: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Edición 20941828449, 2022
Editor: Mary Ann Liebert Inc. publishers

AN INDUCED PLURIPOTENT STEM CELL-BASED MODEL TO STUDY THE MECHANOBIOLOGY OF MYOCARDIAL FIBROSIS

Autores: Francesco Niro, Daniel Pereira De Sousa, Jorge Oliver-De La Cruz, Soraia Fernandes, Stefania Pagliari, Marco Cassani, Vladimir Vinarsky, Ece Ergir, Giancarlo Forte
Publicado en: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Edición 62825441237, 2022
Editor: Mary Ann Liebert Inc. publishers

Design of a bioprinted microfluidic chip as a tumor liver model for drug screening

Autores: H. Fernandes, G. Addario, C.Degrassi, M. Rasponi, C. Mota
Publicado en: I CONVEGNO NAZIONALE DELLA SOCIETÀ ITALIANA ORGAN-ON-CHIP – SIOoC2023<, 2023
Editor: SIOoC

BIOPRINTING OF A RENAL IN VITRO MODEL

Autores: Gabriele Addario, Sonja Djudjaj, Silvia Fare’, Peter Boor, Lorenzo Moroni, Carlos Mota
Publicado en: TERMIS 6th World Congress, Edición 15-19/11/2021, 2021
Editor: Termis

iPSC dilated cardiomyopathy model developed in a mechanical active 3D heart-on-chip

Autores: Ferran Lozano-Juan
Publicado en: EUROoCS Annual Meeting 2022, Edición 4-5/07/2022, 2022
Editor: Conference presentation

Perfusion-based bioreactor ex-vivo model of prostate cancer for personalized drug-testing

Autores: Andrea Mazzoleni
Publicado en: ISREC SCCL SYMPOSIUM 2021, Edición 28-31/08/2021, 2021
Editor: EPFL

Generation of a patient-specific cardiac fibrosis model to analyze lncRNA contribution to heart disease

Autores: Daniel Sousa
Publicado en: Annual International PhD Conference in Biomedical Sciences, Edición 3-5/11/2021, 2021
Editor: Masaryk University

Contribution of Fibronectin alternative splicing isoforms to myocardial fibrosis

Autores: Francesco Niro
Publicado en: nnual International PhD Conference in Biomedical Sciences, Edición 3-5/11/2021, 2021
Editor: Masaryk University

Contractile force measurement in a beating heart-on-a-chip

Autores: Rodrigo Torres García, Roberta Visone, Paola Occhetta, Marco Rasponi
Publicado en: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, Edición 277, 2023
Editor: Springer Spektrum

Unveiling the function of the mechanosensor YAP in the activation of cardiac fibroblasts

Autores: Daniel Sousa, Francesco Niro, Ece Ergir, Jorge Oliver De La Cruz, Stefania Pagliari, Soraia Fernandes, Marco Cassani, Giancarlo Forte
Publicado en: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Edición 28-31/03/2023, 2023
Editor: The University of Manchester

3D intestine-on-chip endothelium device to study gut microbiome interactions

Autores: Karol Kugiejko, Mattia Ballerini, Luigi Nezi, Marco Rasponi
Publicado en: Alternatives to Laboratory Animals - Special Edición: JRC Summer School 2021, Edición Volume 49 Edición 6, November 2021, 2021
Editor: SAGE journals

3D vessel-gut-on-chip platform investigating interactions between immunological system and tumoral tissue remodelling and angiogenesis

Autores: Karol Kugiejko, Mattia Ballerini, Luigi Nezi, Marco Rasponi
Publicado en: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, Edición 12, 2023
Editor: Springer Spektrum

Design of a bioprinted microfluidic chip as a tumor liver model for drug screening

Autores: Hélia Fernandes, Gabriele Addario, Cristina Degrassi, Marco Rasponi, Carlos Mota
Publicado en: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, Edición 321, 2023
Editor: Springer Spektrum

Engineering a Perfusion-based Bioreactor System to Study Metastatic Breast Cancer Interactions with Bone Microenvironments

Autores: Evrim Ceren Kabak
Publicado en: ISREC SCCL SYMPOSIUM 2021, Edición 28-31/08/2021, 2021
Editor: EPFL

Towards a novel alternative toxicity model with normothermically perfused ex vivo livers based on whole porcine slaughterhouse organs

Autores: Alicia Ruppelt, Mitch Vaessen, Marco Stijnen, Marco Rasponi
Publicado en: ALTEX Proceedings - Abstracts of the 11th World Congress, Edición 23/08/2021-02/09/2021, 2021
Editor: ALTEX

GENERATION OF A PATIENT-SPECIFIC CARDIAC FIBROSIS MODEL TO ANALYZE LNCRNA CONTRIBUTION TO HEART DISEASE

Autores: Daniel Pereira-Sousa, Francesco Niro, Ece Ergir, Jorge Oliver-De La Cruz, Stefania Pagliari, Giancarlo Forte
Publicado en: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Edición 62825434808, 2022
Editor: Mary Ann Liebert Inc. publishers

An induced pluripotent stem cell-based model to study the role of extracellular matrix inmyocardial fibrosis

Autores: Francesco Niro, Soraia Fernandes, Jorge Oliver De La Cruz, Marco Cassani, Daniel Pereira De Sousa, Stefania Pagliari, Vladimir Vinarsky, Marco Rasponi, Paola Occhetta, Giulio Pompilio, Elena Sommariva, Davide Rovina, Zbyněk Zdráhal, Ferran Lozano Juan, Giancarlo Forte
Publicado en: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Edición 28-31/03/2023, 2023
Editor: The University of Manchester

TOWARDS A NOVEL ALTERNATIVE TOXICITY MODEL WITH NORMOTHERMICALLY PERFUSED EX VIVO LIVERS BASED ON WHOLE PORCINE SLAUGHTERHOUSE ORGANS

Autores: Alicia Ruppelt, Marco Stijnen, Marco Rasponi, Melanie Krüger
Publicado en: TERMIS 6th World Congress, Edición 15-19/11/2021, 2021
Editor: Termis

Engineering High Throughput System to Study Drug Response of Metastasis Breast Cancer in Bone Microenvironments

Autores: Evrim Ceren Kabak
Publicado en: DBM PhD Retreat, University of Basel, Switzerland, Edición 08-10/10/2020, 2020
Editor: DBM PhD Retreat

It is time to have 3D humanized bioprinted renal fibrosis in vitro models!

Autores: Gabriele Addario
Publicado en: It is time to have 3D humanized bioprinted renal fibrosis in vitro models!, Edición 31/10/2023, 2023
Editor: Conference proceeding

AN INDUCED PLURIPOTENT STEM CELL-BASED MODEL TO STUDY THE MECHANOBIOLOGY OF MYOCARDIAL FIBROSIS

Autores: Francesco Niro
Publicado en: Annual International PhD Conference in Biomedical Sciences, Masaryk University, Brno, 2022, 2022
Editor: Conference presentation

Bioprinted chip as a modern approach for studying kidney fibrosis

Autores: Gabriele Addario
Publicado en: International Conference on Biofabrication 2022, Edición 25-28/09/2022, 2022
Editor: Conference presentation

Development of a PDMS platform to support 3D spheroid generation

Autores: Hélia Fernandes
Publicado en: International Conference on Biofabrication 2022, Edición 25-28/09/2022, 2022
Editor: Conference presentation

AN INDUCED PLURIPOTENT STEM CELL-BASED MODEL TO STUDY THE MECHANOBIOLOGY OF MYOCARDIAL FIBROSIS

Autores: Francesco Niro
Publicado en: JRC Summer School on “Non-animal Approaches in Science - Towards Sustainable Innovation 2023, Edición 23-26/05/2023, 2023
Editor: Conference presentation

Towards a renal tubulointerstitium in vitro model

Autores: Gabriele Addario
Publicado en: Termis workshop Brno online, Edición 10-11/06/2021, 2021
Editor: Conference presentation

Micro-Precision Electro Array (uPEA) platform for heart-on-chip recording

Autores: Ferran Lozano
Publicado en: EUROoCS Annual Meeting 2021, Edición 01-02/07/2021, 2021
Editor: Conference presentation

3D bioprinted human renal tubulointerstitial model to study fibrosis: providing alternatives to in vivo models

Autores: Gabriele Addario
Publicado en: NBTE Annual Meeting 2023, Edición 30/11/2023-01/12/2023, 2023
Editor: Conference presentation

Perfusion bioreactor as a prospective platform for rapid and personalised drug-testing on patient-derived prostate cancer tissue

Autores: Andrea Mazzoleni
Publicado en: BaCell 3D, Basel, Edición 12-13/05/2022, 2022
Editor: Conference presentation

Microfluidic bioprinting of a renal tubulointerstitium in vitro model

Autores: Gabriele Addario
Publicado en: ESB 2021-31st Conference of the ESB, Edición 05/09/2021, 2021
Editor: Conference presentation

Bioprinting self-aggregating kidney progenitor cells within an alginate filament

Autores: Helen Kearney
Publicado en: International Conference on Biofabrication 2022, Edición 25-28/09/2022, 2022
Editor: Conference presentation

Driving innovation

Autores: Alicia Ruppelt
Publicado en: 3rd joint Meeting BELSECT/NESECC, Edición 24/09/2022, 2022
Editor: Conference presentation

Characterization of in vitro drug toxicity and metabolism through a new liver-on-chip model

Autores: Elisa Cauli
Publicado en: EUROoCS Annual Meeting 2022, Edición 4-5/07/2022, 2022
Editor: Conference presentation

Kidney tubulointerstitium: a microfluidic bioprinting approach

Autores: Gabriele Addario
Publicado en: 3D Bioprinting Conference 2021, Edición 26/01/21, 2021
Editor: Conference presentation

Generation of the first design concept of a liver-on-chip for assessing drug toxicity and metabolism in the hepatobiliary environment

Autores: Elisa Cauli
Publicado en: JRC Summer School on non-animal approaches in science: “The three R…evolution”, Edición 17-21/05/2021, 2021
Editor: Poster presentation

Biofabrication of a meso-scale human 3D in vitro model of skeletal muscle for the study of muscular fibrosis

Autores: Riccardo Francescato
Publicado en: 11th Research and Innovation Day in Human Medicine of Southern Switzerland, Edición 03/06/2022, 2022
Editor: Conference presentation

Production of a reusable micromolded microcavity insert to standardize spheroid generation for drug screening

Autores: Hélia Fernandes
Publicado en: Joint 3R Symposium, Edición 19-21/09/2023, 2023
Editor: Conference presentation

Development of a platform to generate thousands of 3D spheroids for bioprinted liver model for drug efficacy and safety assessment

Autores: Hélia Fernandes
Publicado en: JRC Summer School on “Non-animal Approaches in Science - Towards Sustainable Innovation 2023, Edición 23-26/05/2023, 2023
Editor: Conference presentation

Extracellular matrix stiffening effect on epithelial and fibroblast cells during kidney fibrosis

Autores: Gabriele Addario
Publicado en: JRC Summer School on “Non-animal Approaches in Science - Towards Sustainable Innovation 2023, Edición 23-26/05/2023, 2023
Editor: Conference presentation

CONTRACTILE FORCE MEASUREMENT IN A BEATING HEART-ON-A-CHIP

Autores: Rodrigo Torres
Publicado en: JRC Summer School on “Non-animal Approaches in Science - Towards Sustainable Innovation 2023, Edición 23-26/05/2023, 2023
Editor: Conference presentation

Ex vivo Liver Perfusion for Research Purposes: Can We Use Slaughterhouse Material to Reduce Animal Testing?

Autores: Alicia Ruppelt
Publicado en: ASAIO 67th Annual Congress - American Society of Artificial Internal Organs, Edición 08-11/06/2022, 2022
Editor: Conference presentation

Biofabrication of a bone marrow model for breast cancer bone metastasis personalized medicine

Autores: Anaïs Lamouline
Publicado en: 11th Research and Innovation Day in Human Medicine, Edición 03/06/2022, 2022
Editor: Conference presentation

Tubulointerstitium kidney model for future disease screening

Autores: Gabriele Addario
Publicado en: NBTE 2022, Edición 04-05/04/2022, 2022
Editor: Conference presentation

The effect of iPSC culture conditions prior to downstream kidney organoid differentiation

Autores: Helen Kearney
Publicado en: Termis workshop Brno online, Edición 10-11/06/2021, 2021
Editor: Conference presentation

Perfusion bioreactor as a prospective platform for rapid and personalised drug-testing on patient-derived prostate cancer tissue

Autores: Andrea Mazzoleni
Publicado en: DBE Research Day, University of Basel, Edición 30/08/2022, 2022
Editor: Conference presentation

A further investigation into the use of dimethyl sulfoxide prior to the differentiation of induced pluripotent stem cells into renal organoids

Autores: Helen Kearney
Publicado en: NWO life conference 2022, Edición 24-25/05/2022, 2022
Editor: Conference presentation

Improving human kidney fibrosis in vitro models: a mechanical, protein, gene study

Autores: Gabriele Addario
Publicado en: NBTE 2022, Edición 01-02/12/2022, 2022
Editor: Conference presentation

Mesofluidic platform for the skeletal muscle fibrosis modeling

Autores: Riccardo Francescato
Publicado en: 10th Research and Innovation Day in Human Medicine of Southern Switzerland, Edición june 2021, 2021
Editor: Conference presentation

Bioprinting a kidney rudiment for safety drug screening

Autores: Helen Kearney
Publicado en: JRC Summer School on “Non-animal Approaches in Science - Towards Sustainable Innovation 2023, Edición 23-26/05/2023, 2023
Editor: Conference presentation

A further investigation into the use of dimethyl sulfoxide prior to the differentiation of induced pluripotent stem cells into renal organoids

Autores: Helen Kearney
Publicado en: NWO life conference 2022, Netherlands 2022, Edición 24-25/05/2022, 2022
Editor: Conference presentation

3D in vitro model to study skeletal muscle fibrosis

Autores: Riccardo Francescato
Publicado en: 26th Annual Meeting of the Swiss Society for Biomaterials and Regenerative Medicine (SSB+RM2022), Edición 7-9/06/2022, 2022
Editor: Conference presentation

Perfusion bioreactor as a prospective platform for rapid and personalised drug-testing on patient-derived prostate cancer tissue

Autores: Andrea Mazzoleni
Publicado en: Biointerfaces 2022, Edición 13-15/09/2022, 2022
Editor: Conference presentation

A renal tubulointerstitium in vitro model: hope or reality?

Autores: Gabriele Addario
Publicado en: Biofabrication 2021, Edición 27-29/09/2021, 2021
Editor: Conference presentation

uHeart: a novel heart on chip coupled with uniaxial mechanical stimulation and an integrated electrical reading system for drug cardiotoxicity studies

Autores: Ferran Lozano
Publicado en: Termis workshop Brno online, Edición 10-11/06/2021, 2021
Editor: Conference presentation

Kidney Tubulointerstitium In Vitro Model – Current Challenges and Future Prospectives?

Autores: Gabriele Addario
Publicado en: Aspect BioSystems Symposium 2021 Online, Edición October 2021, 2021
Editor: Conference presentation

Biofabrication of a meso-scale human 3D in vitro model of skeletal muscle for the study of muscular fibrosis

Autores: Riccardo Francescato
Publicado en: International Conference on Biofabrication 2022, Edición 25-28/09/2022, 2022
Editor: Conference presentation

In vitro models of breast cancer bone metastasis: analyzing drug resistance through the lens of the microenvironment

Autores: Anaïs Lamouline; Anaïs Lamouline; Anaïs Lamouline; Simone Bersini; Simone Bersini; Simone Bersini; Matteo Moretti; Matteo Moretti; Matteo Moretti; Matteo Moretti
Publicado en: Frontiers in Oncology, Edición 13, 2023, ISSN 2234-943X
Editor: Frontiers Media S. A.
DOI: 10.3389/fonc.2023.1135401

Generation and maturation of human iPSC-derived 3D organotypic cardiac microtissues in long-term culture

Autores: Ece Ergir, Jorge Oliver-De La Cruz, Soraia Fernandes, Marco Cassani, Francesco Niro, Daniel Pereira-Sousa, Jan Vrbský, Vladimír Vinarský, Ana Rubina Perestrelo, Doriana Debellis, Natália Vadovičová, Stjepan Uldrijan, Francesca Cavalieri, Stefania Pagliari, Heinz Redl, Peter Ertl, Giancarlo Forte
Publicado en: Scientific Reports, Edición 12, 2022, Página(s) 21, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-022-22225-w

Bioprinting of kidney in vitro models: cells, biomaterials, and manufacturing techniques.

Autores: Fransen MFJ, Addario G, Bouten CVC, Halary F, Moroni L, Mota C
Publicado en: Essays in Biochemistry, 2021, ISSN 0071-1365
Editor: Portland Press, Ltd.
DOI: 10.1042/ebc20200158

Predicting human cardiac QT alterations and pro-arrhythmic effects of compounds with a 3D beating heart-on-chip platform

Autores: Roberta Visone, Ferran Lozano-Juan, Simona Marzorati, Massimo Walter Rivolta, Enrico Pesenti, Alberto Redaelli, Roberto Sassi, Marco Rasponi, Paola Occhetta
Publicado en: Toxicological Sciences, Edición kfac108, 2022, ISSN 1096-6080
Editor: Oxford University Press
DOI: 10.1093/toxsci/kfac108

A microfluidic model of human vascularized breast cancer metastasis to bone for the study of neutrophil-cancer cell interactions

Autores: Martina Crippa, Giuseppe Talò, Anaïs Lamouline, Sara Bolis, Chiara Arrigoni, Simone Bersini, Matteo Moretti
Publicado en: Materials Today Bio, Edición 17, 2022, Página(s) 100460, ISSN 2590-0064
Editor: Elsevier
DOI: 10.1016/j.mtbio.2022.100460

Normothermic Ex Vivo Liver Platform Using Porcine Slaughterhouse Livers for Disease Modeling

Autores: M Krüger, A Ruppelt, B Kappler, E Van Soest, RA Samsom, GCM Grinwis, N Geijsen, JB Helms, M Stijnen, Marco, L Kock, M Rasponi, HS Kooistra
Publicado en: Bioengineering, Edición 9, 2022, Página(s) 471-489, ISSN 2306-5354
Editor: MDPI
DOI: 10.3390/bioengineering9090471

Endothelial-mesenchymal transition in skeletal muscle: Opportunities and challenges from 3D microphysiological systems

Autores: Riccardo Francescato, Matteo Moretti, Simone Bersini
Publicado en: Bioengineering & Translational Medicine, 2024, ISSN 2380-6761
Editor: Wiley
DOI: 10.1002/btm2.10644

Are slaughterhouse-obtained livers suitable for use in <i>ex vivo</i> perfusion research?

Autores: Ruppelt, Alicia; Pijnenburg, Iris; Pappers, Claire; Samsom, Roos-Anne; Kock, Linda; Grinwis, Guy C. M.; Spee, Bart; Rasponi, Marco; Stijnen, Marco
Publicado en: Journal of International Medical Research, Edición Vol 51(4), 2023, ISSN 0300-0605
Editor: Cambridge Medical Publications
DOI: 10.1177/03000605231189651

3D Printed Tubulointerstitium Chip as an In Vitro Testing Platform

Autores: Addario, Gabriele; Eussen, Daphne; Djudjaj, Sonja; Boor, Peter; Moroni, Lorenzo; Mota, Carlos
Publicado en: Macromolecular bioscience, Edición 2300440, 2023, Página(s) 1-12, ISSN 1616-5187
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.202300440

Microfluidic bioprinting towards a renal in vitro model

Autores: Gabriele Addario, Sonja Djudjaj, Silvia Farè, Peter Boor, Lorenzo Moroni, Carlos Mota
Publicado en: Bioprinting, 2020, ISSN 2405-8866
Editor: Elsevier BV
DOI: 10.1016/j.bprint.2020.e00108

Current strategies of mechanical stimulation for maturation of cardiac microtissues

Autores: Maria Carlos-Oliveira, Ferran Lozano-Juan, Paola Occhetta, Roberta Visone, Marco Rasponi
Publicado en: Biophysical Reviews, Edición 13/5, 2021, Página(s) 717-727, ISSN 1867-2450
Editor: Springer Verlag
DOI: 10.1007/s12551-021-00841-6

Maintaining Liver Functionality Ex Vivo: From Platform Design to Appliaction

Autores: Alicia Ruppelt
Publicado en: PhD Thesis in Bioengineering at Politecnico di Milano, 2023
Editor: Politecnico di Milano

Set up and initial qualification of a microfluidic system for assessing drug toxicity and metabolism in the hepatobiliary environment

Autores: Elisa Cauli
Publicado en: PhD Thesis in Bioengineering at Politecnico di Milano, 2024
Editor: Politecnico di Milano

Biofabrication of a 3D in vitro model of human skeletal muscle for fibrosis modeling and drug development

Autores: Riccardo Francescato
Publicado en: PhD Thesis in Bioengineering at Politecnico di Milano, 2024
Editor: Politecnico di Milano

Biofabrication of 3D Human Muscle Model with Vascularization and Endomysium

Autores: Bersini S, Francescato R, Moretti M.
Publicado en: """Organ-on-a-Chip"" in the series ""Methods in Molecular Biology""", 2021, Página(s) 213-230, ISSN 1940-6029
Editor: Springer Nature
DOI: 10.1007/978-1-0716-1693-2_13

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