advanced technologieS for drug dIscovery and precisioN mEdicine: in vitRo modellinG human physiology and diseAse

Development of an ex vivo liver perfusion model for research purposes

Auteurs: Alicia Ruppelt, Alba Pueyo Moliner, Marco Stijnen, Bart Spee, Marco Rasponi
Publié dans: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Numéro 28-31/03/2023, 2023
Éditeur: The University of Manchester

GENERATION AND CHARACTERIZATION OF HUMAN IPSC-DERIVED CARDIAC ORGANOIDS FOR TRANSLATIONAL MEDICINE

Auteurs: Ece Ergir, Soraia Fernandes, Francesco Niro, Daniel Sousa, Jan Vrbsky, Stefania Pagliari, Doriana Debellis, Heinz Redl, Peter Ertl, Giancarlo Forte
Publié dans: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Numéro 83767252566, 2022
Éditeur: Mary Ann Liebert Inc. publishers

A microfluidic model of human vascularized breast cancer metastasis to bone for the study ofimmune-cancer cell interactions

Auteurs: Simone Bersini, Martina Crippa, Giuseppe Talò, Anais Lamouline, Chiara Arrigoni, Matteo Moretti
Publié dans: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, 2023
Éditeur: Springer Spektrum

Patient specific cardiac model of dilated cardiomyopathy in a beating heart-on-chip

Auteurs: Ferran Lozano Juan, Soraia Fernandes, Francesco Niro, Roberta Visone, Giancarlo Forte, Marco Rasponi, Paola Occhetta
Publié dans: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, Numéro 269, 2023
Éditeur: Springer Spektrum

Development and functional characterization of a microphysiological system for assessing in vitro drug toxicity and metabolism in the hepatobiliary environment

Auteurs: Elisa Cauli, Claudia Piutti, Marco Rasponi, Claudio Bernardi
Publié dans: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, Numéro 37, 2023
Éditeur: Springer Spektrum

3D BIOPRINTED CONSTRUCTS TO GENERATE MATURE ORGANOIDS FROM IPSC-DERIVED RENAL PROGENITORS

Auteurs: Chiara Formica, Gabriele Addario, Lorenzo Moroni, Carlos Mota
Publié dans: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Numéro 83767228888, 2022
Éditeur: Mary Ann Liebert Inc. publishers

Perfusion bioreactor as a perspective platform for rapid and personalised drug-testing on patientderived prostate cancer tissue

Auteurs: Andrea Mazzoleni, Manuele Giuseppe Muraro, Arnaud Scherberich, Helge Seifert, Cyrill Rentsch, Lukas Bubendorf, Clémentine Le Magnen, Ivan Martin
Publié dans: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Numéro 28-31/03/2023, 2023
Éditeur: The University of Manchester

Perfusion-based 3D in vitro model to study the interaction between prostate cancer andendothelial cells in the bone metastatic niche

Auteurs: Andrea Mazzoleni, Mathéo Gwinner, Philip Michael Dettinger, Arnaud Scherberich, Clémentine Le Magnen, Ivan Martin, Manuele Giuseppe Muraro
Publié dans: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Numéro 28-31/03/2023, 2023
Éditeur: The University of Manchester

uHeart: a beating heart-on-chip for culturing 3D cardiac microtissues and recording on-line cardiac electrophysiology

Auteurs: Ferran Lozano, Roberta Visone, Simona Marzorati, Enrico Pesenti, Paola Occhetta, Marco Rasponi
Publié dans: Alternatives to Laboratory Animals - Special Numéro: JRC Summer School 2021, Numéro Volume 49 Numéro 6, November 2021, 2021
Éditeur: SAGE journals

Development of a patient-specific lab-on-chip model of dystrophin deficient cardiomyopathy

Auteurs: Maria Carlos Oliveira, Stefano Piazza, Aoife Gowran, Marco Rasponi
Publié dans: Alternatives to Laboratory Animals - Special Numéro: JRC Summer School 2021, Numéro Volume 49 Numéro 6, November 2021, 2021
Éditeur: SAGE journals

Generation of a 3D patient-specific cardiac fibrosis model using iPSCs

Auteurs: Daniel Pereira-Sousa, Francesco Niro, Ece Ergir, Jorge Oliver de la Cruz, Stefania Pagliari, Soraia Fernandes, Marco Cassani, Giancarlo Forte
Publié dans: 8th Advanced Summer School Interrogations at the biointerface: Fibrosis from mechanisms to the clinic, Numéro 21-22/6/2022, 2022
Éditeur: i3s

Development of a platform to generate thousands of 3D spheroids for bioprinted liver model fordrug efficacy and safety assessment

Auteurs: Hélia Barros Fernandes, Gabriele Addario, Filipa Castro Teixeira, Cristina Degrassi, Marco Rasponi, Carlos Domingues Mota
Publié dans: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Numéro 28-31/03/2023, 2023
Éditeur: The University of Manchester

Production of a reusable micromolded microcavity insert to standardize spheroid generation for drug screening

Auteurs: H. Fernandes, V. Valeri, C. Degrassi, M. Rasponi, C. Mota
Publié dans: Biomedical Science and Engineering 2023, Numéro volume 4: 209, 2023
Éditeur: PAGEPress publications

A MICRO-PRECISION ELECTRO ARRAY (ΜPEA) PLATFORM INTEGRATED WITHIN A MECHANICALLY ACTIVE HEART-ON-CHIP FOR MODELLING DILATED CARDIOMYOPATHY

Auteurs: Ferran Lozano-Juan, Roberta Visone, Giancarlo Forte, Paola Occhetta, Marco Rasponi
Publié dans: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Numéro 94238124605, 2022
Éditeur: Mary Ann Liebert Inc. publishers

ENGINEERING AN EX-VIVO PERFUSION-BASED BIOREACTOR SYSTEM FOR DRUG-TESTING ON PATIENT-SPECIFIC CANCER SPECIMENS

Auteurs: Manuele Giuseppe Muraro, Andrea Mazzoleni, Evrim Ceren Kabak, Arnaud Scherberich, Ivan Martin
Publié dans: TERMIS 6th World Congress, Numéro 15-19/11/2021, 2021
Éditeur: Termis

Perfusion-based bioreactor ex-vivo model of prostate cancer for personalized drug-testing

Auteurs: Andrea Mazzoleni
Publié dans: TERMIS 6th World Congress, Numéro 15-19/11/2021, 2021
Éditeur: Termis

Investigating the Determinants of Breast Cancer Dormancy in Bone

Auteurs: Evrim Ceren Kabak, Sherlyn Foo, Manuele Muraro, Tiberius Preca, Arnaud Scherberich, Mohamed Bentires Alj, Ivan Martin
Publié dans: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Numéro 28-31/03/2023, 2023
Éditeur: The University of Manchester

TOWARDS PHYSIOLOGICALLY RELEVANT BIOPRINTED KIDNEY IN VITRO MODELS

Auteurs: Gabriele Addario, Sonja Djudjaj, Peter Boor, Lorenzo Moroni, Carlos Mota
Publié dans: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Numéro 62825432139, 2022
Éditeur: Mary Ann Liebert Inc. publishers

Efficacy of Sorafenib treatment in a 3D hepatic cancer model

Auteurs: H. Fernandes, V. Valeri, C. Degrassi, M. Rasponi, C. Mota
Publié dans: I CONVEGNO NAZIONALE DELLA SOCIETÀ ITALIANA ORGAN-ON-CHIP – SIOoC2023, Numéro 04-05/05/2023, 2023
Éditeur: SIOoC

Design and preliminary characterization of a new liveron-chip model as a valuable additional tool for assessing in vitro drug toxicity and metabolism in a similar physiological environment

Auteurs: Elisa Cauli, Simona Marzorati, Marco Rasponi, Claudio Bernardi1
Publié dans: ALTEX Proceedings: Abstracts of the 1st Microphysiological Systems World Summit, New Orleans, 2022, 2022
Éditeur: Springer

Biomechanically Stimulated 3D Endothelial Gut-on-Chip Platform to Study Immune Interactions

Auteurs: Karol Kugiejko, Mattia Ballerini, Luigi Nezi, Marco Rasponi
Publié dans: EUROoCS Annual Meeting 2022, Numéro 04-05/07/2022, 2022
Éditeur: Conference presentation

BIOMECHANICALLY STIMULATED 3D ENDOTHELIAL GUT-ON-CHIP PLATFORM TO STUDY INTESTINE MICROBIOME AND IMMUNE SYSTEM INTERACTIONS

Auteurs: Karol Kugiejko, Mattia Ballerini, Luigi Nezi, Marco Rasponi
Publié dans: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Numéro 20941828449, 2022
Éditeur: Mary Ann Liebert Inc. publishers

AN INDUCED PLURIPOTENT STEM CELL-BASED MODEL TO STUDY THE MECHANOBIOLOGY OF MYOCARDIAL FIBROSIS

Auteurs: Francesco Niro, Daniel Pereira De Sousa, Jorge Oliver-De La Cruz, Soraia Fernandes, Stefania Pagliari, Marco Cassani, Vladimir Vinarsky, Ece Ergir, Giancarlo Forte
Publié dans: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Numéro 62825441237, 2022
Éditeur: Mary Ann Liebert Inc. publishers

Design of a bioprinted microfluidic chip as a tumor liver model for drug screening

Auteurs: H. Fernandes, G. Addario, C.Degrassi, M. Rasponi, C. Mota
Publié dans: I CONVEGNO NAZIONALE DELLA SOCIETÀ ITALIANA ORGAN-ON-CHIP – SIOoC2023<, 2023
Éditeur: SIOoC

BIOPRINTING OF A RENAL IN VITRO MODEL

Auteurs: Gabriele Addario, Sonja Djudjaj, Silvia Fare’, Peter Boor, Lorenzo Moroni, Carlos Mota
Publié dans: TERMIS 6th World Congress, Numéro 15-19/11/2021, 2021
Éditeur: Termis

iPSC dilated cardiomyopathy model developed in a mechanical active 3D heart-on-chip

Auteurs: Ferran Lozano-Juan
Publié dans: EUROoCS Annual Meeting 2022, Numéro 4-5/07/2022, 2022
Éditeur: Conference presentation

Perfusion-based bioreactor ex-vivo model of prostate cancer for personalized drug-testing

Auteurs: Andrea Mazzoleni
Publié dans: ISREC SCCL SYMPOSIUM 2021, Numéro 28-31/08/2021, 2021
Éditeur: EPFL

Generation of a patient-specific cardiac fibrosis model to analyze lncRNA contribution to heart disease

Auteurs: Daniel Sousa
Publié dans: Annual International PhD Conference in Biomedical Sciences, Numéro 3-5/11/2021, 2021
Éditeur: Masaryk University

Contribution of Fibronectin alternative splicing isoforms to myocardial fibrosis

Auteurs: Francesco Niro
Publié dans: nnual International PhD Conference in Biomedical Sciences, Numéro 3-5/11/2021, 2021
Éditeur: Masaryk University

Contractile force measurement in a beating heart-on-a-chip

Auteurs: Rodrigo Torres García, Roberta Visone, Paola Occhetta, Marco Rasponi
Publié dans: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, Numéro 277, 2023
Éditeur: Springer Spektrum

Unveiling the function of the mechanosensor YAP in the activation of cardiac fibroblasts

Auteurs: Daniel Sousa, Francesco Niro, Ece Ergir, Jorge Oliver De La Cruz, Stefania Pagliari, Soraia Fernandes, Marco Cassani, Giancarlo Forte
Publié dans: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Numéro 28-31/03/2023, 2023
Éditeur: The University of Manchester

3D intestine-on-chip endothelium device to study gut microbiome interactions

Auteurs: Karol Kugiejko, Mattia Ballerini, Luigi Nezi, Marco Rasponi
Publié dans: Alternatives to Laboratory Animals - Special Numéro: JRC Summer School 2021, Numéro Volume 49 Numéro 6, November 2021, 2021
Éditeur: SAGE journals

3D vessel-gut-on-chip platform investigating interactions between immunological system and tumoral tissue remodelling and angiogenesis

Auteurs: Karol Kugiejko, Mattia Ballerini, Luigi Nezi, Marco Rasponi
Publié dans: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, Numéro 12, 2023
Éditeur: Springer Spektrum

Design of a bioprinted microfluidic chip as a tumor liver model for drug screening

Auteurs: Hélia Fernandes, Gabriele Addario, Cristina Degrassi, Marco Rasponi, Carlos Mota
Publié dans: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, Numéro 321, 2023
Éditeur: Springer Spektrum

Engineering a Perfusion-based Bioreactor System to Study Metastatic Breast Cancer Interactions with Bone Microenvironments

Auteurs: Evrim Ceren Kabak
Publié dans: ISREC SCCL SYMPOSIUM 2021, Numéro 28-31/08/2021, 2021
Éditeur: EPFL

Towards a novel alternative toxicity model with normothermically perfused ex vivo livers based on whole porcine slaughterhouse organs

Auteurs: Alicia Ruppelt, Mitch Vaessen, Marco Stijnen, Marco Rasponi
Publié dans: ALTEX Proceedings - Abstracts of the 11th World Congress, Numéro 23/08/2021-02/09/2021, 2021
Éditeur: ALTEX

GENERATION OF A PATIENT-SPECIFIC CARDIAC FIBROSIS MODEL TO ANALYZE LNCRNA CONTRIBUTION TO HEART DISEASE

Auteurs: Daniel Pereira-Sousa, Francesco Niro, Ece Ergir, Jorge Oliver-De La Cruz, Stefania Pagliari, Giancarlo Forte
Publié dans: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Numéro 62825434808, 2022
Éditeur: Mary Ann Liebert Inc. publishers

An induced pluripotent stem cell-based model to study the role of extracellular matrix inmyocardial fibrosis

Auteurs: Francesco Niro, Soraia Fernandes, Jorge Oliver De La Cruz, Marco Cassani, Daniel Pereira De Sousa, Stefania Pagliari, Vladimir Vinarsky, Marco Rasponi, Paola Occhetta, Giulio Pompilio, Elena Sommariva, Davide Rovina, Zbyněk Zdráhal, Ferran Lozano Juan, Giancarlo Forte
Publié dans: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Numéro 28-31/03/2023, 2023
Éditeur: The University of Manchester

TOWARDS A NOVEL ALTERNATIVE TOXICITY MODEL WITH NORMOTHERMICALLY PERFUSED EX VIVO LIVERS BASED ON WHOLE PORCINE SLAUGHTERHOUSE ORGANS

Auteurs: Alicia Ruppelt, Marco Stijnen, Marco Rasponi, Melanie Krüger
Publié dans: TERMIS 6th World Congress, Numéro 15-19/11/2021, 2021
Éditeur: Termis

Engineering High Throughput System to Study Drug Response of Metastasis Breast Cancer in Bone Microenvironments

Auteurs: Evrim Ceren Kabak
Publié dans: DBM PhD Retreat, University of Basel, Switzerland, Numéro 08-10/10/2020, 2020
Éditeur: DBM PhD Retreat

It is time to have 3D humanized bioprinted renal fibrosis in vitro models!

Auteurs: Gabriele Addario
Publié dans: It is time to have 3D humanized bioprinted renal fibrosis in vitro models!, Numéro 31/10/2023, 2023
Éditeur: Conference proceeding

AN INDUCED PLURIPOTENT STEM CELL-BASED MODEL TO STUDY THE MECHANOBIOLOGY OF MYOCARDIAL FIBROSIS

Auteurs: Francesco Niro
Publié dans: Annual International PhD Conference in Biomedical Sciences, Masaryk University, Brno, 2022, 2022
Éditeur: Conference presentation

Bioprinted chip as a modern approach for studying kidney fibrosis

Auteurs: Gabriele Addario
Publié dans: International Conference on Biofabrication 2022, Numéro 25-28/09/2022, 2022
Éditeur: Conference presentation

Development of a PDMS platform to support 3D spheroid generation

Auteurs: Hélia Fernandes
Publié dans: International Conference on Biofabrication 2022, Numéro 25-28/09/2022, 2022
Éditeur: Conference presentation

AN INDUCED PLURIPOTENT STEM CELL-BASED MODEL TO STUDY THE MECHANOBIOLOGY OF MYOCARDIAL FIBROSIS

Auteurs: Francesco Niro
Publié dans: JRC Summer School on “Non-animal Approaches in Science - Towards Sustainable Innovation 2023, Numéro 23-26/05/2023, 2023
Éditeur: Conference presentation

Towards a renal tubulointerstitium in vitro model

Auteurs: Gabriele Addario
Publié dans: Termis workshop Brno online, Numéro 10-11/06/2021, 2021
Éditeur: Conference presentation

Micro-Precision Electro Array (uPEA) platform for heart-on-chip recording

Auteurs: Ferran Lozano
Publié dans: EUROoCS Annual Meeting 2021, Numéro 01-02/07/2021, 2021
Éditeur: Conference presentation

3D bioprinted human renal tubulointerstitial model to study fibrosis: providing alternatives to in vivo models

Auteurs: Gabriele Addario
Publié dans: NBTE Annual Meeting 2023, Numéro 30/11/2023-01/12/2023, 2023
Éditeur: Conference presentation

Perfusion bioreactor as a prospective platform for rapid and personalised drug-testing on patient-derived prostate cancer tissue

Auteurs: Andrea Mazzoleni
Publié dans: BaCell 3D, Basel, Numéro 12-13/05/2022, 2022
Éditeur: Conference presentation

Microfluidic bioprinting of a renal tubulointerstitium in vitro model

Auteurs: Gabriele Addario
Publié dans: ESB 2021-31st Conference of the ESB, Numéro 05/09/2021, 2021
Éditeur: Conference presentation

Bioprinting self-aggregating kidney progenitor cells within an alginate filament

Auteurs: Helen Kearney
Publié dans: International Conference on Biofabrication 2022, Numéro 25-28/09/2022, 2022
Éditeur: Conference presentation

Driving innovation

Auteurs: Alicia Ruppelt
Publié dans: 3rd joint Meeting BELSECT/NESECC, Numéro 24/09/2022, 2022
Éditeur: Conference presentation

Characterization of in vitro drug toxicity and metabolism through a new liver-on-chip model

Auteurs: Elisa Cauli
Publié dans: EUROoCS Annual Meeting 2022, Numéro 4-5/07/2022, 2022
Éditeur: Conference presentation

Kidney tubulointerstitium: a microfluidic bioprinting approach

Auteurs: Gabriele Addario
Publié dans: 3D Bioprinting Conference 2021, Numéro 26/01/21, 2021
Éditeur: Conference presentation

Generation of the first design concept of a liver-on-chip for assessing drug toxicity and metabolism in the hepatobiliary environment

Auteurs: Elisa Cauli
Publié dans: JRC Summer School on non-animal approaches in science: “The three R…evolution”, Numéro 17-21/05/2021, 2021
Éditeur: Poster presentation

Biofabrication of a meso-scale human 3D in vitro model of skeletal muscle for the study of muscular fibrosis

Auteurs: Riccardo Francescato
Publié dans: 11th Research and Innovation Day in Human Medicine of Southern Switzerland, Numéro 03/06/2022, 2022
Éditeur: Conference presentation

Production of a reusable micromolded microcavity insert to standardize spheroid generation for drug screening

Auteurs: Hélia Fernandes
Publié dans: Joint 3R Symposium, Numéro 19-21/09/2023, 2023
Éditeur: Conference presentation

Development of a platform to generate thousands of 3D spheroids for bioprinted liver model for drug efficacy and safety assessment

Auteurs: Hélia Fernandes
Publié dans: JRC Summer School on “Non-animal Approaches in Science - Towards Sustainable Innovation 2023, Numéro 23-26/05/2023, 2023
Éditeur: Conference presentation

Extracellular matrix stiffening effect on epithelial and fibroblast cells during kidney fibrosis

Auteurs: Gabriele Addario
Publié dans: JRC Summer School on “Non-animal Approaches in Science - Towards Sustainable Innovation 2023, Numéro 23-26/05/2023, 2023
Éditeur: Conference presentation

CONTRACTILE FORCE MEASUREMENT IN A BEATING HEART-ON-A-CHIP

Auteurs: Rodrigo Torres
Publié dans: JRC Summer School on “Non-animal Approaches in Science - Towards Sustainable Innovation 2023, Numéro 23-26/05/2023, 2023
Éditeur: Conference presentation

Ex vivo Liver Perfusion for Research Purposes: Can We Use Slaughterhouse Material to Reduce Animal Testing?

Auteurs: Alicia Ruppelt
Publié dans: ASAIO 67th Annual Congress - American Society of Artificial Internal Organs, Numéro 08-11/06/2022, 2022
Éditeur: Conference presentation

Biofabrication of a bone marrow model for breast cancer bone metastasis personalized medicine

Auteurs: Anaïs Lamouline
Publié dans: 11th Research and Innovation Day in Human Medicine, Numéro 03/06/2022, 2022
Éditeur: Conference presentation

Tubulointerstitium kidney model for future disease screening

Auteurs: Gabriele Addario
Publié dans: NBTE 2022, Numéro 04-05/04/2022, 2022
Éditeur: Conference presentation

The effect of iPSC culture conditions prior to downstream kidney organoid differentiation

Auteurs: Helen Kearney
Publié dans: Termis workshop Brno online, Numéro 10-11/06/2021, 2021
Éditeur: Conference presentation

Perfusion bioreactor as a prospective platform for rapid and personalised drug-testing on patient-derived prostate cancer tissue

Auteurs: Andrea Mazzoleni
Publié dans: DBE Research Day, University of Basel, Numéro 30/08/2022, 2022
Éditeur: Conference presentation

A further investigation into the use of dimethyl sulfoxide prior to the differentiation of induced pluripotent stem cells into renal organoids

Auteurs: Helen Kearney
Publié dans: NWO life conference 2022, Numéro 24-25/05/2022, 2022
Éditeur: Conference presentation

Improving human kidney fibrosis in vitro models: a mechanical, protein, gene study

Auteurs: Gabriele Addario
Publié dans: NBTE 2022, Numéro 01-02/12/2022, 2022
Éditeur: Conference presentation

Mesofluidic platform for the skeletal muscle fibrosis modeling

Auteurs: Riccardo Francescato
Publié dans: 10th Research and Innovation Day in Human Medicine of Southern Switzerland, Numéro june 2021, 2021
Éditeur: Conference presentation

Bioprinting a kidney rudiment for safety drug screening

Auteurs: Helen Kearney
Publié dans: JRC Summer School on “Non-animal Approaches in Science - Towards Sustainable Innovation 2023, Numéro 23-26/05/2023, 2023
Éditeur: Conference presentation

A further investigation into the use of dimethyl sulfoxide prior to the differentiation of induced pluripotent stem cells into renal organoids

Auteurs: Helen Kearney
Publié dans: NWO life conference 2022, Netherlands 2022, Numéro 24-25/05/2022, 2022
Éditeur: Conference presentation

3D in vitro model to study skeletal muscle fibrosis

Auteurs: Riccardo Francescato
Publié dans: 26th Annual Meeting of the Swiss Society for Biomaterials and Regenerative Medicine (SSB+RM2022), Numéro 7-9/06/2022, 2022
Éditeur: Conference presentation

Perfusion bioreactor as a prospective platform for rapid and personalised drug-testing on patient-derived prostate cancer tissue

Auteurs: Andrea Mazzoleni
Publié dans: Biointerfaces 2022, Numéro 13-15/09/2022, 2022
Éditeur: Conference presentation

A renal tubulointerstitium in vitro model: hope or reality?

Auteurs: Gabriele Addario
Publié dans: Biofabrication 2021, Numéro 27-29/09/2021, 2021
Éditeur: Conference presentation

uHeart: a novel heart on chip coupled with uniaxial mechanical stimulation and an integrated electrical reading system for drug cardiotoxicity studies

Auteurs: Ferran Lozano
Publié dans: Termis workshop Brno online, Numéro 10-11/06/2021, 2021
Éditeur: Conference presentation

Kidney Tubulointerstitium In Vitro Model – Current Challenges and Future Prospectives?

Auteurs: Gabriele Addario
Publié dans: Aspect BioSystems Symposium 2021 Online, Numéro October 2021, 2021
Éditeur: Conference presentation

Biofabrication of a meso-scale human 3D in vitro model of skeletal muscle for the study of muscular fibrosis

Auteurs: Riccardo Francescato
Publié dans: International Conference on Biofabrication 2022, Numéro 25-28/09/2022, 2022
Éditeur: Conference presentation

In vitro models of breast cancer bone metastasis: analyzing drug resistance through the lens of the microenvironment

Auteurs: Anaïs Lamouline; Anaïs Lamouline; Anaïs Lamouline; Simone Bersini; Simone Bersini; Simone Bersini; Matteo Moretti; Matteo Moretti; Matteo Moretti; Matteo Moretti
Publié dans: Frontiers in Oncology, Numéro 13, 2023, ISSN 2234-943X
Éditeur: Frontiers Media S. A.
DOI: 10.3389/fonc.2023.1135401

Generation and maturation of human iPSC-derived 3D organotypic cardiac microtissues in long-term culture

Auteurs: Ece Ergir, Jorge Oliver-De La Cruz, Soraia Fernandes, Marco Cassani, Francesco Niro, Daniel Pereira-Sousa, Jan Vrbský, Vladimír Vinarský, Ana Rubina Perestrelo, Doriana Debellis, Natália Vadovičová, Stjepan Uldrijan, Francesca Cavalieri, Stefania Pagliari, Heinz Redl, Peter Ertl, Giancarlo Forte
Publié dans: Scientific Reports, Numéro 12, 2022, Page(s) 21, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-022-22225-w

Bioprinting of kidney in vitro models: cells, biomaterials, and manufacturing techniques.

Auteurs: Fransen MFJ, Addario G, Bouten CVC, Halary F, Moroni L, Mota C
Publié dans: Essays in Biochemistry, 2021, ISSN 0071-1365
Éditeur: Portland Press, Ltd.
DOI: 10.1042/ebc20200158

Predicting human cardiac QT alterations and pro-arrhythmic effects of compounds with a 3D beating heart-on-chip platform

Auteurs: Roberta Visone, Ferran Lozano-Juan, Simona Marzorati, Massimo Walter Rivolta, Enrico Pesenti, Alberto Redaelli, Roberto Sassi, Marco Rasponi, Paola Occhetta
Publié dans: Toxicological Sciences, Numéro kfac108, 2022, ISSN 1096-6080
Éditeur: Oxford University Press
DOI: 10.1093/toxsci/kfac108

A microfluidic model of human vascularized breast cancer metastasis to bone for the study of neutrophil-cancer cell interactions

Auteurs: Martina Crippa, Giuseppe Talò, Anaïs Lamouline, Sara Bolis, Chiara Arrigoni, Simone Bersini, Matteo Moretti
Publié dans: Materials Today Bio, Numéro 17, 2022, Page(s) 100460, ISSN 2590-0064
Éditeur: Elsevier
DOI: 10.1016/j.mtbio.2022.100460

Normothermic Ex Vivo Liver Platform Using Porcine Slaughterhouse Livers for Disease Modeling

Auteurs: M Krüger, A Ruppelt, B Kappler, E Van Soest, RA Samsom, GCM Grinwis, N Geijsen, JB Helms, M Stijnen, Marco, L Kock, M Rasponi, HS Kooistra
Publié dans: Bioengineering, Numéro 9, 2022, Page(s) 471-489, ISSN 2306-5354
Éditeur: MDPI
DOI: 10.3390/bioengineering9090471

Endothelial-mesenchymal transition in skeletal muscle: Opportunities and challenges from 3D microphysiological systems

Auteurs: Riccardo Francescato, Matteo Moretti, Simone Bersini
Publié dans: Bioengineering & Translational Medicine, 2024, ISSN 2380-6761
Éditeur: Wiley
DOI: 10.1002/btm2.10644

Are slaughterhouse-obtained livers suitable for use in <i>ex vivo</i> perfusion research?

Auteurs: Ruppelt, Alicia; Pijnenburg, Iris; Pappers, Claire; Samsom, Roos-Anne; Kock, Linda; Grinwis, Guy C. M.; Spee, Bart; Rasponi, Marco; Stijnen, Marco
Publié dans: Journal of International Medical Research, Numéro Vol 51(4), 2023, ISSN 0300-0605
Éditeur: Cambridge Medical Publications
DOI: 10.1177/03000605231189651

3D Printed Tubulointerstitium Chip as an In Vitro Testing Platform

Auteurs: Addario, Gabriele; Eussen, Daphne; Djudjaj, Sonja; Boor, Peter; Moroni, Lorenzo; Mota, Carlos
Publié dans: Macromolecular bioscience, Numéro 2300440, 2023, Page(s) 1-12, ISSN 1616-5187
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.202300440

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