advanced technologieS for drug dIscovery and precisioN mEdicine: in vitRo modellinG human physiology and diseAse

Development of an ex vivo liver perfusion model for research purposes

Autori: Alicia Ruppelt, Alba Pueyo Moliner, Marco Stijnen, Bart Spee, Marco Rasponi
Pubblicato in: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Numero 28-31/03/2023, 2023
Editore: The University of Manchester

GENERATION AND CHARACTERIZATION OF HUMAN IPSC-DERIVED CARDIAC ORGANOIDS FOR TRANSLATIONAL MEDICINE

Autori: Ece Ergir, Soraia Fernandes, Francesco Niro, Daniel Sousa, Jan Vrbsky, Stefania Pagliari, Doriana Debellis, Heinz Redl, Peter Ertl, Giancarlo Forte
Pubblicato in: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Numero 83767252566, 2022
Editore: Mary Ann Liebert Inc. publishers

A microfluidic model of human vascularized breast cancer metastasis to bone for the study ofimmune-cancer cell interactions

Autori: Simone Bersini, Martina Crippa, Giuseppe Talò, Anais Lamouline, Chiara Arrigoni, Matteo Moretti
Pubblicato in: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, 2023
Editore: Springer Spektrum

Patient specific cardiac model of dilated cardiomyopathy in a beating heart-on-chip

Autori: Ferran Lozano Juan, Soraia Fernandes, Francesco Niro, Roberta Visone, Giancarlo Forte, Marco Rasponi, Paola Occhetta
Pubblicato in: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, Numero 269, 2023
Editore: Springer Spektrum

Development and functional characterization of a microphysiological system for assessing in vitro drug toxicity and metabolism in the hepatobiliary environment

Autori: Elisa Cauli, Claudia Piutti, Marco Rasponi, Claudio Bernardi
Pubblicato in: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, Numero 37, 2023
Editore: Springer Spektrum

3D BIOPRINTED CONSTRUCTS TO GENERATE MATURE ORGANOIDS FROM IPSC-DERIVED RENAL PROGENITORS

Autori: Chiara Formica, Gabriele Addario, Lorenzo Moroni, Carlos Mota
Pubblicato in: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Numero 83767228888, 2022
Editore: Mary Ann Liebert Inc. publishers

Perfusion bioreactor as a perspective platform for rapid and personalised drug-testing on patientderived prostate cancer tissue

Autori: Andrea Mazzoleni, Manuele Giuseppe Muraro, Arnaud Scherberich, Helge Seifert, Cyrill Rentsch, Lukas Bubendorf, Clémentine Le Magnen, Ivan Martin
Pubblicato in: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Numero 28-31/03/2023, 2023
Editore: The University of Manchester

Perfusion-based 3D in vitro model to study the interaction between prostate cancer andendothelial cells in the bone metastatic niche

Autori: Andrea Mazzoleni, Mathéo Gwinner, Philip Michael Dettinger, Arnaud Scherberich, Clémentine Le Magnen, Ivan Martin, Manuele Giuseppe Muraro
Pubblicato in: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Numero 28-31/03/2023, 2023
Editore: The University of Manchester

uHeart: a beating heart-on-chip for culturing 3D cardiac microtissues and recording on-line cardiac electrophysiology

Autori: Ferran Lozano, Roberta Visone, Simona Marzorati, Enrico Pesenti, Paola Occhetta, Marco Rasponi
Pubblicato in: Alternatives to Laboratory Animals - Special Numero: JRC Summer School 2021, Numero Volume 49 Numero 6, November 2021, 2021
Editore: SAGE journals

Development of a patient-specific lab-on-chip model of dystrophin deficient cardiomyopathy

Autori: Maria Carlos Oliveira, Stefano Piazza, Aoife Gowran, Marco Rasponi
Pubblicato in: Alternatives to Laboratory Animals - Special Numero: JRC Summer School 2021, Numero Volume 49 Numero 6, November 2021, 2021
Editore: SAGE journals

Generation of a 3D patient-specific cardiac fibrosis model using iPSCs

Autori: Daniel Pereira-Sousa, Francesco Niro, Ece Ergir, Jorge Oliver de la Cruz, Stefania Pagliari, Soraia Fernandes, Marco Cassani, Giancarlo Forte
Pubblicato in: 8th Advanced Summer School Interrogations at the biointerface: Fibrosis from mechanisms to the clinic, Numero 21-22/6/2022, 2022
Editore: i3s

Development of a platform to generate thousands of 3D spheroids for bioprinted liver model fordrug efficacy and safety assessment

Autori: Hélia Barros Fernandes, Gabriele Addario, Filipa Castro Teixeira, Cristina Degrassi, Marco Rasponi, Carlos Domingues Mota
Pubblicato in: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Numero 28-31/03/2023, 2023
Editore: The University of Manchester

Production of a reusable micromolded microcavity insert to standardize spheroid generation for drug screening

Autori: H. Fernandes, V. Valeri, C. Degrassi, M. Rasponi, C. Mota
Pubblicato in: Biomedical Science and Engineering 2023, Numero volume 4: 209, 2023
Editore: PAGEPress publications

A MICRO-PRECISION ELECTRO ARRAY (ΜPEA) PLATFORM INTEGRATED WITHIN A MECHANICALLY ACTIVE HEART-ON-CHIP FOR MODELLING DILATED CARDIOMYOPATHY

Autori: Ferran Lozano-Juan, Roberta Visone, Giancarlo Forte, Paola Occhetta, Marco Rasponi
Pubblicato in: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Numero 94238124605, 2022
Editore: Mary Ann Liebert Inc. publishers

ENGINEERING AN EX-VIVO PERFUSION-BASED BIOREACTOR SYSTEM FOR DRUG-TESTING ON PATIENT-SPECIFIC CANCER SPECIMENS

Autori: Manuele Giuseppe Muraro, Andrea Mazzoleni, Evrim Ceren Kabak, Arnaud Scherberich, Ivan Martin
Pubblicato in: TERMIS 6th World Congress, Numero 15-19/11/2021, 2021
Editore: Termis

Perfusion-based bioreactor ex-vivo model of prostate cancer for personalized drug-testing

Autori: Andrea Mazzoleni
Pubblicato in: TERMIS 6th World Congress, Numero 15-19/11/2021, 2021
Editore: Termis

Investigating the Determinants of Breast Cancer Dormancy in Bone

Autori: Evrim Ceren Kabak, Sherlyn Foo, Manuele Muraro, Tiberius Preca, Arnaud Scherberich, Mohamed Bentires Alj, Ivan Martin
Pubblicato in: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Numero 28-31/03/2023, 2023
Editore: The University of Manchester

TOWARDS PHYSIOLOGICALLY RELEVANT BIOPRINTED KIDNEY IN VITRO MODELS

Autori: Gabriele Addario, Sonja Djudjaj, Peter Boor, Lorenzo Moroni, Carlos Mota
Pubblicato in: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Numero 62825432139, 2022
Editore: Mary Ann Liebert Inc. publishers

Efficacy of Sorafenib treatment in a 3D hepatic cancer model

Autori: H. Fernandes, V. Valeri, C. Degrassi, M. Rasponi, C. Mota
Pubblicato in: I CONVEGNO NAZIONALE DELLA SOCIETÀ ITALIANA ORGAN-ON-CHIP – SIOoC2023, Numero 04-05/05/2023, 2023
Editore: SIOoC

Design and preliminary characterization of a new liveron-chip model as a valuable additional tool for assessing in vitro drug toxicity and metabolism in a similar physiological environment

Autori: Elisa Cauli, Simona Marzorati, Marco Rasponi, Claudio Bernardi1
Pubblicato in: ALTEX Proceedings: Abstracts of the 1st Microphysiological Systems World Summit, New Orleans, 2022, 2022
Editore: Springer

Biomechanically Stimulated 3D Endothelial Gut-on-Chip Platform to Study Immune Interactions

Autori: Karol Kugiejko, Mattia Ballerini, Luigi Nezi, Marco Rasponi
Pubblicato in: EUROoCS Annual Meeting 2022, Numero 04-05/07/2022, 2022
Editore: Conference presentation

BIOMECHANICALLY STIMULATED 3D ENDOTHELIAL GUT-ON-CHIP PLATFORM TO STUDY INTESTINE MICROBIOME AND IMMUNE SYSTEM INTERACTIONS

Autori: Karol Kugiejko, Mattia Ballerini, Luigi Nezi, Marco Rasponi
Pubblicato in: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Numero 20941828449, 2022
Editore: Mary Ann Liebert Inc. publishers

AN INDUCED PLURIPOTENT STEM CELL-BASED MODEL TO STUDY THE MECHANOBIOLOGY OF MYOCARDIAL FIBROSIS

Autori: Francesco Niro, Daniel Pereira De Sousa, Jorge Oliver-De La Cruz, Soraia Fernandes, Stefania Pagliari, Marco Cassani, Vladimir Vinarsky, Ece Ergir, Giancarlo Forte
Pubblicato in: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Numero 62825441237, 2022
Editore: Mary Ann Liebert Inc. publishers

Design of a bioprinted microfluidic chip as a tumor liver model for drug screening

Autori: H. Fernandes, G. Addario, C.Degrassi, M. Rasponi, C. Mota
Pubblicato in: I CONVEGNO NAZIONALE DELLA SOCIETÀ ITALIANA ORGAN-ON-CHIP – SIOoC2023<, 2023
Editore: SIOoC

BIOPRINTING OF A RENAL IN VITRO MODEL

Autori: Gabriele Addario, Sonja Djudjaj, Silvia Fare’, Peter Boor, Lorenzo Moroni, Carlos Mota
Pubblicato in: TERMIS 6th World Congress, Numero 15-19/11/2021, 2021
Editore: Termis

iPSC dilated cardiomyopathy model developed in a mechanical active 3D heart-on-chip

Autori: Ferran Lozano-Juan
Pubblicato in: EUROoCS Annual Meeting 2022, Numero 4-5/07/2022, 2022
Editore: Conference presentation

Perfusion-based bioreactor ex-vivo model of prostate cancer for personalized drug-testing

Autori: Andrea Mazzoleni
Pubblicato in: ISREC SCCL SYMPOSIUM 2021, Numero 28-31/08/2021, 2021
Editore: EPFL

Generation of a patient-specific cardiac fibrosis model to analyze lncRNA contribution to heart disease

Autori: Daniel Sousa
Pubblicato in: Annual International PhD Conference in Biomedical Sciences, Numero 3-5/11/2021, 2021
Editore: Masaryk University

Contribution of Fibronectin alternative splicing isoforms to myocardial fibrosis

Autori: Francesco Niro
Pubblicato in: nnual International PhD Conference in Biomedical Sciences, Numero 3-5/11/2021, 2021
Editore: Masaryk University

Contractile force measurement in a beating heart-on-a-chip

Autori: Rodrigo Torres García, Roberta Visone, Paola Occhetta, Marco Rasponi
Pubblicato in: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, Numero 277, 2023
Editore: Springer Spektrum

Unveiling the function of the mechanosensor YAP in the activation of cardiac fibroblasts

Autori: Daniel Sousa, Francesco Niro, Ece Ergir, Jorge Oliver De La Cruz, Stefania Pagliari, Soraia Fernandes, Marco Cassani, Giancarlo Forte
Pubblicato in: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Numero 28-31/03/2023, 2023
Editore: The University of Manchester

3D intestine-on-chip endothelium device to study gut microbiome interactions

Autori: Karol Kugiejko, Mattia Ballerini, Luigi Nezi, Marco Rasponi
Pubblicato in: Alternatives to Laboratory Animals - Special Numero: JRC Summer School 2021, Numero Volume 49 Numero 6, November 2021, 2021
Editore: SAGE journals

3D vessel-gut-on-chip platform investigating interactions between immunological system and tumoral tissue remodelling and angiogenesis

Autori: Karol Kugiejko, Mattia Ballerini, Luigi Nezi, Marco Rasponi
Pubblicato in: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, Numero 12, 2023
Editore: Springer Spektrum

Design of a bioprinted microfluidic chip as a tumor liver model for drug screening

Autori: Hélia Fernandes, Gabriele Addario, Cristina Degrassi, Marco Rasponi, Carlos Mota
Pubblicato in: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, Numero 321, 2023
Editore: Springer Spektrum

Engineering a Perfusion-based Bioreactor System to Study Metastatic Breast Cancer Interactions with Bone Microenvironments

Autori: Evrim Ceren Kabak
Pubblicato in: ISREC SCCL SYMPOSIUM 2021, Numero 28-31/08/2021, 2021
Editore: EPFL

Towards a novel alternative toxicity model with normothermically perfused ex vivo livers based on whole porcine slaughterhouse organs

Autori: Alicia Ruppelt, Mitch Vaessen, Marco Stijnen, Marco Rasponi
Pubblicato in: ALTEX Proceedings - Abstracts of the 11th World Congress, Numero 23/08/2021-02/09/2021, 2021
Editore: ALTEX

GENERATION OF A PATIENT-SPECIFIC CARDIAC FIBROSIS MODEL TO ANALYZE LNCRNA CONTRIBUTION TO HEART DISEASE

Autori: Daniel Pereira-Sousa, Francesco Niro, Ece Ergir, Jorge Oliver-De La Cruz, Stefania Pagliari, Giancarlo Forte
Pubblicato in: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Numero 62825434808, 2022
Editore: Mary Ann Liebert Inc. publishers

An induced pluripotent stem cell-based model to study the role of extracellular matrix inmyocardial fibrosis

Autori: Francesco Niro, Soraia Fernandes, Jorge Oliver De La Cruz, Marco Cassani, Daniel Pereira De Sousa, Stefania Pagliari, Vladimir Vinarsky, Marco Rasponi, Paola Occhetta, Giulio Pompilio, Elena Sommariva, Davide Rovina, Zbyněk Zdráhal, Ferran Lozano Juan, Giancarlo Forte
Pubblicato in: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Numero 28-31/03/2023, 2023
Editore: The University of Manchester

TOWARDS A NOVEL ALTERNATIVE TOXICITY MODEL WITH NORMOTHERMICALLY PERFUSED EX VIVO LIVERS BASED ON WHOLE PORCINE SLAUGHTERHOUSE ORGANS

Autori: Alicia Ruppelt, Marco Stijnen, Marco Rasponi, Melanie Krüger
Pubblicato in: TERMIS 6th World Congress, Numero 15-19/11/2021, 2021
Editore: Termis

Engineering High Throughput System to Study Drug Response of Metastasis Breast Cancer in Bone Microenvironments

Autori: Evrim Ceren Kabak
Pubblicato in: DBM PhD Retreat, University of Basel, Switzerland, Numero 08-10/10/2020, 2020
Editore: DBM PhD Retreat

It is time to have 3D humanized bioprinted renal fibrosis in vitro models!

Autori: Gabriele Addario
Pubblicato in: It is time to have 3D humanized bioprinted renal fibrosis in vitro models!, Numero 31/10/2023, 2023
Editore: Conference proceeding

AN INDUCED PLURIPOTENT STEM CELL-BASED MODEL TO STUDY THE MECHANOBIOLOGY OF MYOCARDIAL FIBROSIS

Autori: Francesco Niro
Pubblicato in: Annual International PhD Conference in Biomedical Sciences, Masaryk University, Brno, 2022, 2022
Editore: Conference presentation

Bioprinted chip as a modern approach for studying kidney fibrosis

Autori: Gabriele Addario
Pubblicato in: International Conference on Biofabrication 2022, Numero 25-28/09/2022, 2022
Editore: Conference presentation

Development of a PDMS platform to support 3D spheroid generation

Autori: Hélia Fernandes
Pubblicato in: International Conference on Biofabrication 2022, Numero 25-28/09/2022, 2022
Editore: Conference presentation

AN INDUCED PLURIPOTENT STEM CELL-BASED MODEL TO STUDY THE MECHANOBIOLOGY OF MYOCARDIAL FIBROSIS

Autori: Francesco Niro
Pubblicato in: JRC Summer School on “Non-animal Approaches in Science - Towards Sustainable Innovation 2023, Numero 23-26/05/2023, 2023
Editore: Conference presentation

Towards a renal tubulointerstitium in vitro model

Autori: Gabriele Addario
Pubblicato in: Termis workshop Brno online, Numero 10-11/06/2021, 2021
Editore: Conference presentation

Micro-Precision Electro Array (uPEA) platform for heart-on-chip recording

Autori: Ferran Lozano
Pubblicato in: EUROoCS Annual Meeting 2021, Numero 01-02/07/2021, 2021
Editore: Conference presentation

3D bioprinted human renal tubulointerstitial model to study fibrosis: providing alternatives to in vivo models

Autori: Gabriele Addario
Pubblicato in: NBTE Annual Meeting 2023, Numero 30/11/2023-01/12/2023, 2023
Editore: Conference presentation

Perfusion bioreactor as a prospective platform for rapid and personalised drug-testing on patient-derived prostate cancer tissue

Autori: Andrea Mazzoleni
Pubblicato in: BaCell 3D, Basel, Numero 12-13/05/2022, 2022
Editore: Conference presentation

Microfluidic bioprinting of a renal tubulointerstitium in vitro model

Autori: Gabriele Addario
Pubblicato in: ESB 2021-31st Conference of the ESB, Numero 05/09/2021, 2021
Editore: Conference presentation

Bioprinting self-aggregating kidney progenitor cells within an alginate filament

Autori: Helen Kearney
Pubblicato in: International Conference on Biofabrication 2022, Numero 25-28/09/2022, 2022
Editore: Conference presentation

Driving innovation

Autori: Alicia Ruppelt
Pubblicato in: 3rd joint Meeting BELSECT/NESECC, Numero 24/09/2022, 2022
Editore: Conference presentation

Characterization of in vitro drug toxicity and metabolism through a new liver-on-chip model

Autori: Elisa Cauli
Pubblicato in: EUROoCS Annual Meeting 2022, Numero 4-5/07/2022, 2022
Editore: Conference presentation

Kidney tubulointerstitium: a microfluidic bioprinting approach

Autori: Gabriele Addario
Pubblicato in: 3D Bioprinting Conference 2021, Numero 26/01/21, 2021
Editore: Conference presentation

Generation of the first design concept of a liver-on-chip for assessing drug toxicity and metabolism in the hepatobiliary environment

Autori: Elisa Cauli
Pubblicato in: JRC Summer School on non-animal approaches in science: “The three R…evolution”, Numero 17-21/05/2021, 2021
Editore: Poster presentation

Biofabrication of a meso-scale human 3D in vitro model of skeletal muscle for the study of muscular fibrosis

Autori: Riccardo Francescato
Pubblicato in: 11th Research and Innovation Day in Human Medicine of Southern Switzerland, Numero 03/06/2022, 2022
Editore: Conference presentation

Production of a reusable micromolded microcavity insert to standardize spheroid generation for drug screening

Autori: Hélia Fernandes
Pubblicato in: Joint 3R Symposium, Numero 19-21/09/2023, 2023
Editore: Conference presentation

Development of a platform to generate thousands of 3D spheroids for bioprinted liver model for drug efficacy and safety assessment

Autori: Hélia Fernandes
Pubblicato in: JRC Summer School on “Non-animal Approaches in Science - Towards Sustainable Innovation 2023, Numero 23-26/05/2023, 2023
Editore: Conference presentation

Extracellular matrix stiffening effect on epithelial and fibroblast cells during kidney fibrosis

Autori: Gabriele Addario
Pubblicato in: JRC Summer School on “Non-animal Approaches in Science - Towards Sustainable Innovation 2023, Numero 23-26/05/2023, 2023
Editore: Conference presentation

CONTRACTILE FORCE MEASUREMENT IN A BEATING HEART-ON-A-CHIP

Autori: Rodrigo Torres
Pubblicato in: JRC Summer School on “Non-animal Approaches in Science - Towards Sustainable Innovation 2023, Numero 23-26/05/2023, 2023
Editore: Conference presentation

Ex vivo Liver Perfusion for Research Purposes: Can We Use Slaughterhouse Material to Reduce Animal Testing?

Autori: Alicia Ruppelt
Pubblicato in: ASAIO 67th Annual Congress - American Society of Artificial Internal Organs, Numero 08-11/06/2022, 2022
Editore: Conference presentation

Biofabrication of a bone marrow model for breast cancer bone metastasis personalized medicine

Autori: Anaïs Lamouline
Pubblicato in: 11th Research and Innovation Day in Human Medicine, Numero 03/06/2022, 2022
Editore: Conference presentation

Tubulointerstitium kidney model for future disease screening

Autori: Gabriele Addario
Pubblicato in: NBTE 2022, Numero 04-05/04/2022, 2022
Editore: Conference presentation

The effect of iPSC culture conditions prior to downstream kidney organoid differentiation

Autori: Helen Kearney
Pubblicato in: Termis workshop Brno online, Numero 10-11/06/2021, 2021
Editore: Conference presentation

Perfusion bioreactor as a prospective platform for rapid and personalised drug-testing on patient-derived prostate cancer tissue

Autori: Andrea Mazzoleni
Pubblicato in: DBE Research Day, University of Basel, Numero 30/08/2022, 2022
Editore: Conference presentation

A further investigation into the use of dimethyl sulfoxide prior to the differentiation of induced pluripotent stem cells into renal organoids

Autori: Helen Kearney
Pubblicato in: NWO life conference 2022, Numero 24-25/05/2022, 2022
Editore: Conference presentation

Improving human kidney fibrosis in vitro models: a mechanical, protein, gene study

Autori: Gabriele Addario
Pubblicato in: NBTE 2022, Numero 01-02/12/2022, 2022
Editore: Conference presentation

Mesofluidic platform for the skeletal muscle fibrosis modeling

Autori: Riccardo Francescato
Pubblicato in: 10th Research and Innovation Day in Human Medicine of Southern Switzerland, Numero june 2021, 2021
Editore: Conference presentation

Bioprinting a kidney rudiment for safety drug screening

Autori: Helen Kearney
Pubblicato in: JRC Summer School on “Non-animal Approaches in Science - Towards Sustainable Innovation 2023, Numero 23-26/05/2023, 2023
Editore: Conference presentation

A further investigation into the use of dimethyl sulfoxide prior to the differentiation of induced pluripotent stem cells into renal organoids

Autori: Helen Kearney
Pubblicato in: NWO life conference 2022, Netherlands 2022, Numero 24-25/05/2022, 2022
Editore: Conference presentation

3D in vitro model to study skeletal muscle fibrosis

Autori: Riccardo Francescato
Pubblicato in: 26th Annual Meeting of the Swiss Society for Biomaterials and Regenerative Medicine (SSB+RM2022), Numero 7-9/06/2022, 2022
Editore: Conference presentation

Perfusion bioreactor as a prospective platform for rapid and personalised drug-testing on patient-derived prostate cancer tissue

Autori: Andrea Mazzoleni
Pubblicato in: Biointerfaces 2022, Numero 13-15/09/2022, 2022
Editore: Conference presentation

A renal tubulointerstitium in vitro model: hope or reality?

Autori: Gabriele Addario
Pubblicato in: Biofabrication 2021, Numero 27-29/09/2021, 2021
Editore: Conference presentation

uHeart: a novel heart on chip coupled with uniaxial mechanical stimulation and an integrated electrical reading system for drug cardiotoxicity studies

Autori: Ferran Lozano
Pubblicato in: Termis workshop Brno online, Numero 10-11/06/2021, 2021
Editore: Conference presentation

Kidney Tubulointerstitium In Vitro Model – Current Challenges and Future Prospectives?

Autori: Gabriele Addario
Pubblicato in: Aspect BioSystems Symposium 2021 Online, Numero October 2021, 2021
Editore: Conference presentation

Biofabrication of a meso-scale human 3D in vitro model of skeletal muscle for the study of muscular fibrosis

Autori: Riccardo Francescato
Pubblicato in: International Conference on Biofabrication 2022, Numero 25-28/09/2022, 2022
Editore: Conference presentation

In vitro models of breast cancer bone metastasis: analyzing drug resistance through the lens of the microenvironment

Autori: Anaïs Lamouline; Anaïs Lamouline; Anaïs Lamouline; Simone Bersini; Simone Bersini; Simone Bersini; Matteo Moretti; Matteo Moretti; Matteo Moretti; Matteo Moretti
Pubblicato in: Frontiers in Oncology, Numero 13, 2023, ISSN 2234-943X
Editore: Frontiers Media S. A.
DOI: 10.3389/fonc.2023.1135401

Generation and maturation of human iPSC-derived 3D organotypic cardiac microtissues in long-term culture

Autori: Ece Ergir, Jorge Oliver-De La Cruz, Soraia Fernandes, Marco Cassani, Francesco Niro, Daniel Pereira-Sousa, Jan Vrbský, Vladimír Vinarský, Ana Rubina Perestrelo, Doriana Debellis, Natália Vadovičová, Stjepan Uldrijan, Francesca Cavalieri, Stefania Pagliari, Heinz Redl, Peter Ertl, Giancarlo Forte
Pubblicato in: Scientific Reports, Numero 12, 2022, Pagina/e 21, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-022-22225-w

Bioprinting of kidney in vitro models: cells, biomaterials, and manufacturing techniques.

Autori: Fransen MFJ, Addario G, Bouten CVC, Halary F, Moroni L, Mota C
Pubblicato in: Essays in Biochemistry, 2021, ISSN 0071-1365
Editore: Portland Press, Ltd.
DOI: 10.1042/ebc20200158

Predicting human cardiac QT alterations and pro-arrhythmic effects of compounds with a 3D beating heart-on-chip platform

Autori: Roberta Visone, Ferran Lozano-Juan, Simona Marzorati, Massimo Walter Rivolta, Enrico Pesenti, Alberto Redaelli, Roberto Sassi, Marco Rasponi, Paola Occhetta
Pubblicato in: Toxicological Sciences, Numero kfac108, 2022, ISSN 1096-6080
Editore: Oxford University Press
DOI: 10.1093/toxsci/kfac108

A microfluidic model of human vascularized breast cancer metastasis to bone for the study of neutrophil-cancer cell interactions

Autori: Martina Crippa, Giuseppe Talò, Anaïs Lamouline, Sara Bolis, Chiara Arrigoni, Simone Bersini, Matteo Moretti
Pubblicato in: Materials Today Bio, Numero 17, 2022, Pagina/e 100460, ISSN 2590-0064
Editore: Elsevier
DOI: 10.1016/j.mtbio.2022.100460

Normothermic Ex Vivo Liver Platform Using Porcine Slaughterhouse Livers for Disease Modeling

Autori: M Krüger, A Ruppelt, B Kappler, E Van Soest, RA Samsom, GCM Grinwis, N Geijsen, JB Helms, M Stijnen, Marco, L Kock, M Rasponi, HS Kooistra
Pubblicato in: Bioengineering, Numero 9, 2022, Pagina/e 471-489, ISSN 2306-5354
Editore: MDPI
DOI: 10.3390/bioengineering9090471

Endothelial-mesenchymal transition in skeletal muscle: Opportunities and challenges from 3D microphysiological systems

Autori: Riccardo Francescato, Matteo Moretti, Simone Bersini
Pubblicato in: Bioengineering & Translational Medicine, 2024, ISSN 2380-6761
Editore: Wiley
DOI: 10.1002/btm2.10644

Are slaughterhouse-obtained livers suitable for use in <i>ex vivo</i> perfusion research?

Autori: Ruppelt, Alicia; Pijnenburg, Iris; Pappers, Claire; Samsom, Roos-Anne; Kock, Linda; Grinwis, Guy C. M.; Spee, Bart; Rasponi, Marco; Stijnen, Marco
Pubblicato in: Journal of International Medical Research, Numero Vol 51(4), 2023, ISSN 0300-0605
Editore: Cambridge Medical Publications
DOI: 10.1177/03000605231189651

3D Printed Tubulointerstitium Chip as an In Vitro Testing Platform

Autori: Addario, Gabriele; Eussen, Daphne; Djudjaj, Sonja; Boor, Peter; Moroni, Lorenzo; Mota, Carlos
Pubblicato in: Macromolecular bioscience, Numero 2300440, 2023, Pagina/e 1-12, ISSN 1616-5187
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.202300440

Microfluidic bioprinting towards a renal in vitro model

Autori: Gabriele Addario, Sonja Djudjaj, Silvia Farè, Peter Boor, Lorenzo Moroni, Carlos Mota
Pubblicato in: Bioprinting, 2020, ISSN 2405-8866
Editore: Elsevier BV
DOI: 10.1016/j.bprint.2020.e00108

Current strategies of mechanical stimulation for maturation of cardiac microtissues

Autori: Maria Carlos-Oliveira, Ferran Lozano-Juan, Paola Occhetta, Roberta Visone, Marco Rasponi
Pubblicato in: Biophysical Reviews, Numero 13/5, 2021, Pagina/e 717-727, ISSN 1867-2450
Editore: Springer Verlag
DOI: 10.1007/s12551-021-00841-6

Maintaining Liver Functionality Ex Vivo: From Platform Design to Appliaction

Autori: Alicia Ruppelt
Pubblicato in: PhD Thesis in Bioengineering at Politecnico di Milano, 2023
Editore: Politecnico di Milano

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Pubblicato in: PhD Thesis in Bioengineering at Politecnico di Milano, 2024
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Autori: Bersini S, Francescato R, Moretti M.
Pubblicato in: """Organ-on-a-Chip"" in the series ""Methods in Molecular Biology""", 2021, Pagina/e 213-230, ISSN 1940-6029
Editore: Springer Nature
DOI: 10.1007/978-1-0716-1693-2_13

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