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Cell-Like ‘Molecular Assembly Lines’ of Programmable Reaction Sequences as Game-Changers in Chemical Synthesis


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Accelerated Reaction Engineering of Photo(bio)catalytic Reactions through Parallelization with an Open-Source Photoreactor

Author(s): Christoph Winkler, Stefan Simić, Valentina Jurkaš, Sarah Bierbaumer, Luca Schmermund, Silvan Poschenrieder, Sarah A. Berger, Elisa Kulterer, Robert Kourist, and Wolfgang Kroutil
Published in: ChemPhotoChem, 2021, ISSN 2367-0932
Publisher: Wiley-VCH GmbH
DOI: 10.1002/cptc.202100109

Shortening Synthetic Routes to Small Molecule Active Pharmaceutical Ingredients Employing Biocatalytic Methods

Author(s): Stefan Simić, Erna Zukić, Luca Schmermund, Kurt Faber, Christoph K. Winkler, and Wolfgang Kroutil
Published in: Chemical Reviews, 2021, ISSN 0009-2665
Publisher: American Chemical Society
DOI: 10.1021/acs.chemrev.1c00574

Amine Catalysis with Substrates Bearing N ‐Heterocyclic Moieties Enabled by Control over the Enamine Pyramidalization Direction

Author(s): Jasper S. Möhler, Tobias Schnitzer, Helma Wennemers
Published in: Chemistry – A European Journal, 26/67, 2020, Page(s) 15623-15628, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202002966

Synergistic Peptide and Gold Catalysis: Enantioselective Addition of Branched Aldehydes to Allenamides

Author(s): Helma Wennemers, Leo Nicholls
Published in: Chemistry - A European Journal, 2021, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202103197

Primitive selection of the fittest emerging through functional synergy in nucleopeptide networks

Author(s): Anil Kumar Bandela; Nathaniel Wagner; Hava Sadihov; Sara Morales-Reina; Agata Chotera-Ouda; Kingshuk Basu; Rivka Cohen-Luria; Andrés de la Escosura; Gonen Ashkenasy
Published in: Proc Natl Acad Sci U S A, 2021, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2015285118

Reversible Photoswitchable Inhibitors Generate Ultrasensitivity in Out-Of-Equilibrium Enzymatic Reactions

Author(s): Michael Teders, Aleksandr A. Pogodaev, Glenn Bojanov, Wilhelm T. S. Huck
Published in: Journal of the American Chemical Society, 2021, ISSN 1520-5126
Publisher: American Chemical Society
DOI: 10.1021/jacs.0c12956

Reversible Photoswitchable Inhibitors Enable Wavelength-Selective Regulation of Out-of-Equilibrium Bi-Enzymatic Systems

Author(s): Michael Teders, Nicholas M. Murray, Wilhelm T. S. Huck
Published in: ChemSystemsChem, 2021, ISSN 2570-4206
Publisher: Wiley-VCH GmbH
DOI: 10.1002/syst.202100020