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Cell-Like ‘Molecular Assembly Lines’ of Programmable Reaction Sequences as Game-Changers in Chemical Synthesis

Deliverables

Dissemination and Exploitation Plan

The Dissemination and Exploitation Plan (DEP) is due at the end of the first reporting period and is updated every reporting period.

Project website and logo

Set up and maintain a project website that serves as an information resource for the general public, the scientific community and other stakeholders and includes a secured area for consortium internal exchange of documents.

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Publications

Accelerated Reaction Engineering of Photo(bio)catalytic Reactions through Parallelization with an Open-Source Photoreactor

Author(s): Christoph Winkler, Stefan Simić, Valentina Jurkaš, Sarah Bierbaumer, Luca Schmermund, Silvan Poschenrieder, Sarah A. Berger, Elisa Kulterer, Robert Kourist, and Wolfgang Kroutil
Published in: ChemPhotoChem, 2021, ISSN 2367-0932
Publisher: Wiley-VCH GmbH
DOI: 10.1002/cptc.202100109

Shortening Synthetic Routes to Small Molecule Active Pharmaceutical Ingredients Employing Biocatalytic Methods

Author(s): Stefan Simić, Erna Zukić, Luca Schmermund, Kurt Faber, Christoph K. Winkler, and Wolfgang Kroutil
Published in: Chemical Reviews, 2021, ISSN 0009-2665
Publisher: American Chemical Society
DOI: 10.1021/acs.chemrev.1c00574

Amine Catalysis with Substrates Bearing N ‐Heterocyclic Moieties Enabled by Control over the Enamine Pyramidalization Direction

Author(s): Jasper S. Möhler, Tobias Schnitzer, Helma Wennemers
Published in: Chemistry – A European Journal, 26/67, 2020, Page(s) 15623-15628, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202002966

Synergistic Peptide and Gold Catalysis: Enantioselective Addition of Branched Aldehydes to Allenamides

Author(s): Helma Wennemers, Leo Nicholls
Published in: Chemistry - A European Journal, 2021, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202103197

Primitive selection of the fittest emerging through functional synergy in nucleopeptide networks

Author(s): Anil Kumar Bandela; Nathaniel Wagner; Hava Sadihov; Sara Morales-Reina; Agata Chotera-Ouda; Kingshuk Basu; Rivka Cohen-Luria; Andrés de la Escosura; Gonen Ashkenasy
Published in: Proc Natl Acad Sci U S A, 2021, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2015285118

Reversible Photoswitchable Inhibitors Generate Ultrasensitivity in Out-Of-Equilibrium Enzymatic Reactions

Author(s): Michael Teders, Aleksandr A. Pogodaev, Glenn Bojanov, Wilhelm T. S. Huck
Published in: Journal of the American Chemical Society, 2021, ISSN 1520-5126
Publisher: American Chemical Society
DOI: 10.1021/jacs.0c12956

Reversible Photoswitchable Inhibitors Enable Wavelength-Selective Regulation of Out-of-Equilibrium Bi-Enzymatic Systems

Author(s): Michael Teders, Nicholas M. Murray, Wilhelm T. S. Huck
Published in: ChemSystemsChem, 2021, ISSN 2570-4206
Publisher: Wiley-VCH GmbH
DOI: 10.1002/syst.202100020