Chirality via Cross-Coupling: New Asymmetric C-C Bond Formations Driven by Atom and Step Economy

Project Information

ChiCC

Grant agreement ID: 863799

DOI

10.3030/863799

EC signature date 3 March 2020

Start date 1 September 2020

End date 28 February 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 999 890,00

EU contribution

€ 1 999 890,00

Coordinated by

THE UNIVERSITY OF LIVERPOOL
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (1)

Data Management Plan

ORDP Deliverable

Publications

Peer reviewed articles (5)

A directed enolization strategy enables by-product-free construction of contiguous stereocentres en route to complex amino acids

Author(s): Fenglin Hong, Timothy P. Aldhous, Paul D. Kemmitt, John F. Bower
Published in: Nature Chemistry, Issue 16, 2024, Page(s) 1125-1132, ISSN 1755-4330
Publisher: Nature Publishing Group
DOI: 10.1038/s41557-024-01473-5

Iridium-Catalyzed Enantioselective Alkene Hydroalkylation via a Heteroaryl-Directed Enolization–Decarboxylation Sequence

Author(s): Changcheng Jing, Wenbin Mao, and John F. Bower*
Published in: Journal of the American Chemical Society, 2023, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.3c10163

Enantioselective Intermolecular Murai-Type Alkene Hydroarylation Reactions

Author(s): Timothy P. Aldhous , Raymond W. M. Chung , Andrew G. Dalling , John F. Bower
Published in: Synthesis, 2021, ISSN 0039-7881
Publisher: Georg Thieme Verlag
DOI: 10.1055/s-0040-1720406

Atom and step economical synthesis of acyclic quaternary centers <i>via</i> iridium-catalyzed hydroarylative cross-coupling of 1,1-disubstituted alkenes

Author(s): Phillippa Cooper; Andrew G. Dalling; Elliot H. E. Farrar; Timothy P. Aldhous; Simon Grélaud; Eleanor Lester; Lyman J. Feron; Paul D. Kemmitt; Matthew N. Grayson; John F. Bower
Published in: Chemical Science, Issue 1, 2022, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2sc02790a

An Aza-Enolate Strategy Enables Iridium-Catalyzed Enantioselective Hydroalkenylations of Minimally Polarized Alkenes en Route to Complex N-Aryl β²-Amino Acids

Author(s): Fenglin Hong, Craig M. Robertson, John F. Bower
Published in: Journal of the American Chemical Society, Issue 146, 2024, Page(s) 22923-22929, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.4c07519