A directed enolization strategy enables by-product-free construction of contiguous stereocentres en route to complex amino acids
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Autori:
Fenglin Hong, Timothy P. Aldhous, Paul D. Kemmitt, John F. Bower
Pubblicato in:
Nature Chemistry, Numero 16, 2024, Pagina/e 1125-1132, ISSN 1755-4330
Editore:
Nature Publishing Group
DOI:
10.1038/s41557-024-01473-5
Iridium-Catalyzed Enantioselective Alkene Hydroalkylation via a Heteroaryl-Directed Enolization–Decarboxylation Sequence
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Autori:
Changcheng Jing, Wenbin Mao, and John F. Bower*
Pubblicato in:
Journal of the American Chemical Society, 2023, ISSN 0002-7863
Editore:
American Chemical Society
DOI:
10.1021/jacs.3c10163
Enantioselective Intermolecular Murai-Type Alkene Hydroarylation Reactions
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Autori:
Timothy P. Aldhous , Raymond W. M. Chung , Andrew G. Dalling , John F. Bower
Pubblicato in:
Synthesis, 2021, ISSN 0039-7881
Editore:
Georg Thieme Verlag
DOI:
10.1055/s-0040-1720406
Atom and step economical synthesis of acyclic quaternary centers <i>via</i> iridium-catalyzed hydroarylative cross-coupling of 1,1-disubstituted alkenes
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Autori:
Phillippa Cooper; Andrew G. Dalling; Elliot H. E. Farrar; Timothy P. Aldhous; Simon Grélaud; Eleanor Lester; Lyman J. Feron; Paul D. Kemmitt; Matthew N. Grayson; John F. Bower
Pubblicato in:
Chemical Science, Numero 1, 2022, ISSN 2041-6520
Editore:
Royal Society of Chemistry
DOI:
10.1039/d2sc02790a
An Aza-Enolate Strategy Enables Iridium-Catalyzed Enantioselective Hydroalkenylations of Minimally Polarized Alkenes en Route to Complex N-Aryl β<sup>2</sup>-Amino Acids
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Autori:
Fenglin Hong, Craig M. Robertson, John F. Bower
Pubblicato in:
Journal of the American Chemical Society, Numero 146, 2024, Pagina/e 22923-22929, ISSN 0002-7863
Editore:
American Chemical Society
DOI:
10.1021/jacs.4c07519