Chirality via Cross-Coupling: New Asymmetric C-C Bond Formations Driven by Atom and Step Economy

Información del proyecto

ChiCC

Identificador del acuerdo de subvención: 863799

DOI 10.3030/863799

Fecha de la firma de la CE 3 Marzo 2020

Fecha de inicio 1 Septiembre 2020

Fecha de finalización 31 Agosto 2025

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total € 1 999 890,00

Aportación de la UE € 1 999 890,00

Coordinado por

THE UNIVERSITY OF LIVERPOOL
United Kingdom

Resultado final

Open Research Data Pilot (1)

Data Management Plan

ORDP Deliverable

Publicaciones

Peer reviewed articles (5)

A directed enolization strategy enables by-product-free construction of contiguous stereocentres en route to complex amino acids

Autores: Fenglin Hong, Timothy P. Aldhous, Paul D. Kemmitt, John F. Bower
Publicado en: Nature Chemistry, Edición 16, 2024, Página(s) 1125-1132, ISSN 1755-4330
Editor: Nature Publishing Group
DOI: 10.1038/s41557-024-01473-5

Iridium-Catalyzed Enantioselective Alkene Hydroalkylation via a Heteroaryl-Directed Enolization–Decarboxylation Sequence

Autores: Changcheng Jing, Wenbin Mao, and John F. Bower*
Publicado en: Journal of the American Chemical Society, 2023, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.3c10163

Enantioselective Intermolecular Murai-Type Alkene Hydroarylation Reactions

Autores: Timothy P. Aldhous , Raymond W. M. Chung , Andrew G. Dalling , John F. Bower
Publicado en: Synthesis, 2021, ISSN 0039-7881
Editor: Georg Thieme Verlag
DOI: 10.1055/s-0040-1720406

Atom and step economical synthesis of acyclic quaternary centers <i>via</i> iridium-catalyzed hydroarylative cross-coupling of 1,1-disubstituted alkenes

Autores: Phillippa Cooper; Andrew G. Dalling; Elliot H. E. Farrar; Timothy P. Aldhous; Simon Grélaud; Eleanor Lester; Lyman J. Feron; Paul D. Kemmitt; Matthew N. Grayson; John F. Bower
Publicado en: Cooper , P , Dalling , A G , Farrar , E H E , Aldhous , T P , Grélaud , S , Lester , E , Feron , L J , Kemmitt , P D , Grayson , M N & Bower , J F 2022 , ' Atom and step economical synthesis of acyclic quaternary centers via iridium-catalyzed hydroarylative cross-coupling of 1,1-disubstituted alkenes ' , Chemical Science , vol. 13 , no. 37 , pp. 11183-11189 . https://doi.org/10.1039/D2SC02790A, Edición 1, 2022, ISSN 2041-6520
Editor: Royal Society of Chemistry
DOI: 10.1039/d2sc02790a

An Aza-Enolate Strategy Enables Iridium-Catalyzed Enantioselective Hydroalkenylations of Minimally Polarized Alkenes en Route to Complex N-Aryl β²-Amino Acids

Autores: Fenglin Hong, Craig M. Robertson, John F. Bower
Publicado en: Journal of the American Chemical Society, Edición 146, 2024, Página(s) 22923-22929, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.4c07519