Mechanical Biomarkers for Prediction of Cancer Immunotherapy

Publications

The Role of Tumor Microenvironment in Cancer Metastasis: Molecular Mechanisms and Therapeutic Opportunities

Auteurs: Christiana M. Neophytou, Myrofora Panagi, Triantafyllos Stylianopoulos, Panagiotis Papageorgis
Publié dans: Cancers, Numéro 13/9, 2021, Page(s) 2053, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13092053

Nanomechanical properties of solid tumors as treatment monitoring biomarkers

Auteurs: Andreas Stylianou, Fotios Mpekris, Chrysovalantis Voutouri, Antonia Papoui, Anastasia Constantinidou, Evros Kitiris, Michalis Kailides, Triantafyllos Stylianopoulos
Publié dans: Acta Biomaterialia, Numéro 17427061, 2022, ISSN 1742-7061
Éditeur: Elsevier BV
DOI: 10.1016/j.actbio.2022.10.021

Normalizing tumor microenvironment with nanomedicine and metronomic therapy to improve immunotherapy

Auteurs: Mpekris F., C. Voutouri, M. Panagi, J.W Baish, R.K Jain, T. Stylianopoulos
Publié dans: Journal of Controlled Release, Numéro 01683659, 2022, ISSN 0168-3659
Éditeur: Elsevier BV
DOI: 10.1016/j.jconrel.2022.03.008

Endothelin Inhibition Potentiates Cancer Immunotherapy Revealing Mechanical Biomarkers Predictive of Response

Auteurs: Chrysovalantis Voutouri, Myrofora Panagi, Fotios Mpekris, Andreas Stylianou, Christina Michael, Michalakis A. Averkiou, John D. Martin, Triantafyllos Stylianopoulos
Publié dans: Advanced Therapeutics, Numéro 2000289, 2021, Page(s) 2000289, ISSN 2366-3987
Éditeur: Wiley-VCH
DOI: 10.1002/adtp.202000289

Normalizing the Microenvironment Overcomes Vessel Compression and Resistance to Nano‐immunotherapy in Breast Cancer Lung Metastasis

Auteurs: Fotios Mpekris, Myrofora Panagi, Chrysovalantis Voutouri, John D. Martin, Rekha Samuel, Shinichiro Takahashi, Naoto Gotohda, Toshiyuki Suzuki, Panagiotis Papageorgis, Philippos Demetriou, Chryso Pierides, Laura Koumas, Paul Costeas, Motohiro Kojima, Genichiro Ishii, Anastasia Constantinidou, Kazunori Kataoka, Horacio Cabral, Triantafyllos Stylianopoulos
Publié dans: Advanced Science, Numéro 8/3, 2021, Page(s) 2001917, ISSN 2198-3844
Éditeur: Wiley-VCH
DOI: 10.1002/advs.202001917

Polymeric micelles effectively reprogram the tumor microenvironment to potentiate nano-immunotherapy in mouse breast cancer models

Auteurs: Myrofora Panagi, Fotios Mpekris, Pengwen Chen, Chrysovalantis Voutouri, Yasuhiro Nakagawa, John D. Martin, Tetsuro Hiroi, Hiroko Hashimoto, Philippos Demetriou, Chryso Pierides, Rekha Samuel, Andreas Stylianou, Christina Michael, Shigeto Fukushima, Paraskevi Georgiou, Panagiotis Papageorgis, Petri Ch. Papaphilippou, Laura Koumas, Paul Costeas, Genichiro Ishii, Motohiro Kojima, Kazunori Kataoka, Ho
Publié dans: Nature Communications, 2022, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-022-34744-1

Exploring the landscape of immunotherapy approaches in sarcomas

Auteurs: Pampina Pilavaki, Myrofora Panagi, Samia Arifi, Robin L. Jones, Triantafyllos Stylianopoulos, Anastasia Constantinidou
Publié dans: Frontiers in Oncology, 2023, ISSN 2234-943X
Éditeur: Frontiers Media S. A.
DOI: 10.3389/fonc.2022.1069963

Mechanical stress signaling in pancreatic cancer cells triggers p38 MAPK- and JNK-dependent cytoskeleton remodeling and promotes cell migration via Rac1/Cdc42/Myosin II

Auteurs: Kalli M., R. Li, G.B. Mills, T. Stylianopoulos, I.K. Zervantonakis
Publié dans: Molecular Cancer Research, Numéro 15417786, 2022, ISSN 1541-7786
Éditeur: American Association for Cancer Research
DOI: 10.1158/1541-7786.mcr-21-0266

Inducing Biomechanical Heterogeneity in Brain Tumor Modeling by MR Elastography: Effects on Tumor Growth, Vascular Density and Delivery of Therapeutics

Auteurs: Harkos, C.; Svensson, S.F., Emblem, K.E., and Stylianopoulos, T.
Publié dans: Cancers, Numéro 20726694, 2022, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14040884

Immunotherapy in soft tissue and bone sarcoma: unraveling the barriers to effectiveness

Auteurs: Panagi M., P. Pilavaki, A. Constantinidou, T. Stylianopoulos
Publié dans: Theranostics, Numéro 18387640, 2022, ISSN 1838-7640
Éditeur: Ivyspring International Publisher
DOI: 10.7150/thno.72800

Pancreatic Cancer Presents Distinct Nanomechanical Properties During Progression

Auteurs: Andreas Stylianou; Chrysovalantis Voutouri; Fotios Mpekris; Triantafyllos Stylianopoulos
Publié dans: Annals of Biomedical Engineering, Numéro 1, 2023, ISSN 1573-9686
Éditeur: Springer
DOI: 10.1007/s10439-023-03168-3

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