Mechanical Biomarkers for Prediction of Cancer Immunotherapy | Immuno-Predictor | Projekt | Wyniki | H2020 | CORDIS

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Publikacje

The Role of Tumor Microenvironment in Cancer Metastasis: Molecular Mechanisms and Therapeutic Opportunities

Autorzy: Christiana M. Neophytou, Myrofora Panagi, Triantafyllos Stylianopoulos, Panagiotis Papageorgis
Opublikowane w: Cancers, Numer 13/9, 2021, Strona(/y) 2053, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13092053

Dynamic heterogeneity in COVID-19: Insights from a mathematical model

Autorzy: Chrysovalantis Voutouri, C. Corey Hardin, Vivek Naranbhai, Mohammad R. Nikmaneshi, Melin J. Khandekar, Justin F. Gainor, Lance L. Munn, Rakesh K. Jain, Triantafyllos Stylianopoulos
Opublikowane w: PLOS ONE, Numer 19, 2024, Strona(/y) e0301780, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0301780

Mathematical modeling of intratumoral immunotherapy yields strategies to improve the treatment outcomes

Autorzy: Constantinos Harkos, Triantafyllos Stylianopoulos, Rakesh K. Jain
Opublikowane w: PLOS Computational Biology, Numer 19, 2024, Strona(/y) e1011740, ISSN 1553-7358
Wydawca: Public Library of Science (PLoS)
DOI: 10.1371/journal.pcbi.1011740

Ultrasound stiffness and perfusion markers correlate with tumor volume responses to immunotherapy

Autorzy: Chrysovalantis Voutouri, Fotios Mpekris, Myrofora Panagi, Connor Krolak, Christina Michael, John D. Martin, Michalakis A. Averkiou, Triantafyllos Stylianopoulos
Opublikowane w: Acta Biomaterialia, Numer 167, 2024, Strona(/y) 121-134, ISSN 1742-7061
Wydawca: Elsevier BV
DOI: 10.1016/j.actbio.2023.06.007

Pirfenidone-Loaded Polymeric Micelles as an Effective Mechanotherapeutic to Potentiate Immunotherapy in Mouse Tumor Models

Autorzy: Fotios Mpekris, Petri Ch. Papaphilippou, Myrofora Panagi, Chrysovalantis Voutouri, Christina Michael, Antonia Charalambous, Mariyan Marinov Dinev, Anna Katsioloudi, Marianna Prokopi-Demetriades, Andreas Anayiotos, Horacio Cabral, Theodora Krasia-Christoforou, Triantafyllos Stylianopoulos
Opublikowane w: ACS Nano, Numer 17, 2023, Strona(/y) 24654-24667, ISSN 1936-0851
Wydawca: American Chemical Society
DOI: 10.1021/acsnano.3c03305

Mechanical forces inducing oxaliplatin resistance in pancreatic cancer can be targeted by autophagy inhibition

Autorzy: Maria Kalli, Fotios Mpekris, Antonia Charalambous, Christina Michael, Chrystalla Stylianou, Chrysovalantis Voutouri, Andreas G. Hadjigeorgiou, Antonia Papoui, John D. Martin, Triantafyllos Stylianopoulos
Opublikowane w: Communications Biology, Numer 7, 2024, ISSN 2399-3642
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/s42003-024-07268-1

Nanomechanical properties of solid tumors as treatment monitoring biomarkers

Autorzy: Andreas Stylianou, Fotios Mpekris, Chrysovalantis Voutouri, Antonia Papoui, Anastasia Constantinidou, Evros Kitiris, Michalis Kailides, Triantafyllos Stylianopoulos
Opublikowane w: Acta Biomaterialia, Numer 17427061, 2022, ISSN 1742-7061
Wydawca: Elsevier BV
DOI: 10.1016/j.actbio.2022.10.021

Modulating cancer mechanopathology to restore vascular function and enhance immunotherapy

Autorzy: Fotios Mpekris, Myrofora Panagi, Antonia Charalambous, Chrysovalantis Voutouri, Triantafyllos Stylianopoulos
Opublikowane w: Cell Reports Medicine, Numer 5, 2024, Strona(/y) 101626, ISSN 2666-3791
Wydawca: Cell
DOI: 10.1016/j.xcrm.2024.101626

Normalizing tumor microenvironment with nanomedicine and metronomic therapy to improve immunotherapy

Autorzy: Mpekris F., C. Voutouri, M. Panagi, J.W Baish, R.K Jain, T. Stylianopoulos
Opublikowane w: Journal of Controlled Release, Numer 01683659, 2022, ISSN 0168-3659
Wydawca: Elsevier BV
DOI: 10.1016/j.jconrel.2022.03.008

Endothelin Inhibition Potentiates Cancer Immunotherapy Revealing Mechanical Biomarkers Predictive of Response

Autorzy: Chrysovalantis Voutouri, Myrofora Panagi, Fotios Mpekris, Andreas Stylianou, Christina Michael, Michalakis A. Averkiou, John D. Martin, Triantafyllos Stylianopoulos
Opublikowane w: Advanced Therapeutics, Numer 2000289, 2021, Strona(/y) 2000289, ISSN 2366-3987
Wydawca: Wiley-VCH
DOI: 10.1002/adtp.202000289

Normalizing the Microenvironment Overcomes Vessel Compression and Resistance to Nano‐immunotherapy in Breast Cancer Lung Metastasis

Autorzy: Fotios Mpekris, Myrofora Panagi, Chrysovalantis Voutouri, John D. Martin, Rekha Samuel, Shinichiro Takahashi, Naoto Gotohda, Toshiyuki Suzuki, Panagiotis Papageorgis, Philippos Demetriou, Chryso Pierides, Laura Koumas, Paul Costeas, Motohiro Kojima, Genichiro Ishii, Anastasia Constantinidou, Kazunori Kataoka, Horacio Cabral, Triantafyllos Stylianopoulos
Opublikowane w: Advanced Science, Numer 8/3, 2021, Strona(/y) 2001917, ISSN 2198-3844
Wydawca: Wiley-VCH
DOI: 10.1002/advs.202001917

Convection-Enhanced Delivery in silico study for personalized brain cancer treatment

Autorzy: Chryso Lambride, Vasileios Vavourakis, Triantafyllos Stylianopoulos
Opublikowane w: Frontiers in Bioengineering and Biotechnology, 2022, ISSN 2296-4185
Wydawca: Frontiers
DOI: 10.21203/rs.3.rs-998895/v1

Machine learning analysis reveals tumor stiffness and hypoperfusion as biomarkers predictive of cancer treatment efficacy

Autorzy: Demetris Englezos, Chrysovalantis Voutouri, Triantafyllos Stylianopoulos
Opublikowane w: Translational Oncology, Numer 44, 2024, Strona(/y) 101944, ISSN 1936-5233
Wydawca: Neoplasia Press
DOI: 10.1016/j.tranon.2024.101944

Hybrid model of tumor growth, angiogenesis and immune response yields strategies to improve antiangiogenic therapy

Autorzy: Andreas G. Hadjigeorgiou, Triantafyllos Stylianopoulos
Opublikowane w: npj Biological Physics and Mechanics, Numer 1, 2024, ISSN 3004-863X
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/s44341-024-00002-2

Polymeric micelles effectively reprogram the tumor microenvironment to potentiate nano-immunotherapy in mouse breast cancer models

Autorzy: Myrofora Panagi, Fotios Mpekris, Pengwen Chen, Chrysovalantis Voutouri, Yasuhiro Nakagawa, John D. Martin, Tetsuro Hiroi, Hiroko Hashimoto, Philippos Demetriou, Chryso Pierides, Rekha Samuel, Andreas Stylianou, Christina Michael, Shigeto Fukushima, Paraskevi Georgiou, Panagiotis Papageorgis, Petri Ch. Papaphilippou, Laura Koumas, Paul Costeas, Genichiro Ishii, Motohiro Kojima, Kazunori Kataoka, Ho
Opublikowane w: Nature Communications, 2022, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-022-34744-1

Stabilizing Tumor-Resident Mast Cells Restores T-Cell Infiltration and Sensitizes Sarcomas to PD-L1 Inhibition

Autorzy: Myrofora Panagi, Fotios Mpekris, Chrysovalantis Voutouri, Andreas G. Hadjigeorgiou, Chloe Symeonidou, Eleni Porfyriou, Christina Michael, Andreas Stylianou, John D. Martin, Horacio Cabral, Anastasia Constantinidou, Triantafyllos Stylianopoulos
Opublikowane w: Clinical Cancer Research, Numer 30, 2024, Strona(/y) 2582-2597, ISSN 1078-0432
Wydawca: American Association for Cancer Research
DOI: 10.1158/1078-0432.ccr-24-0246

Investigating the synergistic effects of immunotherapy and normalization treatment in modulating tumor microenvironment and enhancing treatment efficacy

Autorzy: Constantinos Harkos, Triantafyllos Stylianopoulos
Opublikowane w: Journal of Theoretical Biology, Numer 583, 2024, Strona(/y) 111768, ISSN 0022-5193
Wydawca: Academic Press
DOI: 10.1016/j.jtbi.2024.111768

Exploring the landscape of immunotherapy approaches in sarcomas

Autorzy: Pampina Pilavaki, Myrofora Panagi, Samia Arifi, Robin L. Jones, Triantafyllos Stylianopoulos, Anastasia Constantinidou
Opublikowane w: Frontiers in Oncology, 2023, ISSN 2234-943X
Wydawca: Frontiers Media S. A.
DOI: 10.3389/fonc.2022.1069963

Mechanical stress signaling in pancreatic cancer cells triggers p38 MAPK- and JNK-dependent cytoskeleton remodeling and promotes cell migration via Rac1/Cdc42/Myosin II

Autorzy: Kalli M., R. Li, G.B. Mills, T. Stylianopoulos, I.K. Zervantonakis
Opublikowane w: Molecular Cancer Research, Numer 15417786, 2022, ISSN 1541-7786
Wydawca: American Association for Cancer Research
DOI: 10.1158/1541-7786.mcr-21-0266

Inducing Biomechanical Heterogeneity in Brain Tumor Modeling by MR Elastography: Effects on Tumor Growth, Vascular Density and Delivery of Therapeutics

Autorzy: Harkos, C.; Svensson, S.F., Emblem, K.E., and Stylianopoulos, T.
Opublikowane w: Cancers, Numer 20726694, 2022, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14040884

In silico clinical studies for optimal COVID-19 vaccination schedules in patients with cancer

Autorzy: Chrysovalantis Voutouri, C. Corey Hardin, Vivek Naranbhai, Mohammad R. Nikmaneshi, Melin J. Khandekar, Justin F. Gainor, Triantafyllos Stylianopoulos, Lance L. Munn, Rakesh K. Jain
Opublikowane w: Cell Reports Medicine, Numer 5, 2024, Strona(/y) 101436, ISSN 2666-3791
Wydawca: Elsevier BV
DOI: 10.1016/j.xcrm.2024.101436

Vascular Normalization to Improve Treatment of COVID-19: Lessons from Treatment of Cancer

Autorzy: Lance L. Munn, Triantafyllos Stylianopoulos, Natalie K. Jain, C. Corey Hardin, Melin J. Khandekar, Rakesh K. Jain
Opublikowane w: Clinical Cancer Research, Numer 27, 2022, Strona(/y) 2706-2711, ISSN 1078-0432
Wydawca: American Association for Cancer Research
DOI: 10.1158/1078-0432.ccr-20-4750

Mechanistic model for booster doses effectiveness in healthy, cancer, and immunosuppressed patients infected with SARS-CoV-2

Autorzy: Chrysovalantis Voutouri, C. Corey Hardin, Vivek Naranbhai, Mohammad R. Nikmaneshi, Melin J. Khandekar, Justin F. Gainor, Triantafyllos Stylianopoulos, Lance L. Munn, Rakesh K. Jain
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 120, 2023, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.2211132120

Immunotherapy in soft tissue and bone sarcoma: unraveling the barriers to effectiveness

Autorzy: Panagi M., P. Pilavaki, A. Constantinidou, T. Stylianopoulos
Opublikowane w: Theranostics, Numer 18387640, 2022, ISSN 1838-7640
Wydawca: Ivyspring International Publisher
DOI: 10.7150/thno.72800

A synergistic approach for modulating the tumor microenvironment to enhance nano-immunotherapy in sarcomas

Autorzy: Fotios Mpekris, Myrofora Panagi, Antonia Charalambous, Chrysovalantis Voutouri, Christina Michael, Antonia Papoui, Triantafyllos Stylianopoulos
Opublikowane w: Neoplasia, Numer 51, 2024, Strona(/y) 100990, ISSN 1476-5586
Wydawca: Elsevier
DOI: 10.1016/j.neo.2024.100990

In silico dynamics of COVID-19 phenotypes for optimizing clinical management

Autorzy: Chrysovalantis Voutouri, Mohammad Reza Nikmaneshi, C. Corey Hardin, Ankit B. Patel, Ashish Verma, Melin J. Khandekar, Sayon Dutta, Triantafyllos Stylianopoulos, Lance L. Munn, Rakesh K. Jain
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 118, 2022, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.2021642118

Toward innovative approaches for exploring the mechanically regulated tumor-immune microenvironment

Autorzy: Maria Kalli, Triantafyllos Stylianopoulos
Opublikowane w: APL Bioengineering, Numer 8, 2025, ISSN 2473-2877
Wydawca: AIP Publishing
DOI: 10.1063/5.0183302

Pancreatic Cancer Presents Distinct Nanomechanical Properties During Progression

Autorzy: Andreas Stylianou; Chrysovalantis Voutouri; Fotios Mpekris; Triantafyllos Stylianopoulos
Opublikowane w: Annals of Biomedical Engineering, Numer 1, 2023, ISSN 1573-9686
Wydawca: Springer
DOI: 10.1007/s10439-023-03168-3

Beyond matrix stiffness: targeting force-induced cancer drug resistance

Autorzy: Maria Kalli, Matthew D. Poskus, Triantafyllos Stylianopoulos, Ioannis K. Zervantonakis
Opublikowane w: Trends in Cancer, Numer 9, 2024, Strona(/y) 937-954, ISSN 2405-8033
Wydawca: Elsevier BV
DOI: 10.1016/j.trecan.2023.07.006

Evaluation of growth-induced, mechanical stress in solid tumors and spatial association with extracellular matrix content

Autorzy: Andreas G. Hadjigeorgiou, Triantafyllos Stylianopoulos
Opublikowane w: Biomechanics and Modeling in Mechanobiology, Numer 22, 2023, Strona(/y) 1625-1643, ISSN 1617-7959
Wydawca: Springer Verlag
DOI: 10.1007/s10237-023-01716-3

Dissecting the Impact of the Gut Microbiome on Cancer Immunotherapy

Autorzy: Rakesh Jain, Andreas Hadjigeorgiou, Constantinos Harkos, Aditya Mishra, Golnaz Morad, Sarah Johnson, Nadim Ajami, Jennifer Wargo, Lance Munn, Triantafyllos Stylianopoulos
Opublikowane w: 2024
Wydawca: Research Square Platform LLC
DOI: 10.21203/rs.3.rs-3647386/v1

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