Bioinorganic intracellular synthesis of photo-responsive bio-camouflaged nanomedicines

Informazioni relative al progetto

NanoBioMade

ID dell’accordo di sovvenzione: 865629

DOI

10.3030/865629

Data della firma CE 19 Febbraio 2020

Data di avvio 1 Febbraio 2021

Data di completamento 31 Gennaio 2027

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 1 967 000,00

Contributo UE

€ 1 967 000,00

Coordinato da

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (19)

Elucidating the Dynamics of Biodegradation and Biosynthesis of Magnetic Nanoparticles in Human Stem Cells

Autori: Alberto Curcio, Guilhem Curé, Ana Espinosa, Nicolas Menguy, Itziar Galarreta‐Rodriguez, Ali Abou‐Hassan, Bérénice Piquet, Laurence Motte, Yoann Lalatonne, Claire Wilhelm, Aurore Van de Walle
Pubblicato in: Small, Numero 20, 2025, ISSN 1613-6810
Editore: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202407034

Zn doped iron oxide nanoparticles with high magnetization and photothermal efficiency for cancer treatment

Autori: Georgios Kasparis; Anouchka Plan Sangnier; Lilin Wang; Christoforos Efstathiou; Alec P. LaGrow; Andreas Sergides; Claire Wilhelm; Nguyen Thi Kim Thanh
Pubblicato in: Journal of Materials Chemistry B, 2023, ISSN 2050-750X
Editore: royal society of chemistry
DOI: 10.1039/d2tb01338j

Magnetic bioprinting of stem cell-based tissues

Autori: Aurore Van de Walle, Jose Efrain Perez, Claire Wilhelm
Pubblicato in: Bioprinting, 2023, ISSN 2405-8866
Editore: Elsevier
DOI: 10.1016/j.bprint.2023.e00265

Biomineralization of magnetic nanoparticles in stem cells

Autori: Alexandre Fromain, Aurore Van de Walle, Guilhem Curé, Christine Péchoux, Aida Serrano, Yoann Lalatonne, Ana Espinosa and Claire Wilhelm
Pubblicato in: Nanoscale, 2023, ISSN 2040-3372
Editore: Royal Society of Chemistry
DOI: 10.1039/d3nr00863k

Design and evaluation of multi-core raspberry-like platinum nanoparticles for enhanced photothermal treatment

Autori: Erwann Guénin, Alexandre Fromain, Aida Serrano, Giacomo Gropplero, Yoann Lalatonne, Ana Espinosa, Claire Wilhelm
Pubblicato in: Communications Materials, Numero 4, 2023, ISSN 2662-4443
Editore: Springer Science and Business Media LLC
DOI: 10.1038/s43246-023-00411-1

High‐Yield Bioproduction of Extracellular Vesicles from Stem Cell Spheroids via Millifluidic Vortex Transport

Autori: Elliot Thouvenot, Laura Charnay, Noa Burshtein, Jean‐Michel Guigner, Léonie Dec, Damarys Loew, Amanda K.A. Silva, Anke Lindner, Claire Wilhelm
Pubblicato in: Advanced Materials, Numero 37, 2025, ISSN 0935-9648
Editore: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202412498

Photothermia at the nanoscale induces ferroptosis via nanoparticle degradation

Autori: Alexandre Fromain, Jose Efrain Perez, Aurore Van de Walle, Yoann Lalatonne & Claire Wilhelm
Pubblicato in: Nature Communication, 2023, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-023-40258-1

Label‐Free Machine Learning Prediction of Chemotherapy on Tumor Spheroids Using a Microfluidics Droplet Platform

Autori: Caroline Parent, Hasti Honari, Tiziana Tocci, Franck Simon, Sakina Zaidi, Audric Jan, Vivian Aubert, Olivier Delattre, Hervé Isambert, Claire Wilhelm, Jean‐Louis Viovy
Pubblicato in: Small Science, Numero 5, 2025, ISSN 2688-4046
Editore: Wiley
DOI: 10.1002/smsc.202500173

Simple droplet microfluidics platform for drug screening on cancer spheroids

Autori: Caroline Parent, Kiran Raj Melayil, Ya Zhou, Vivian Aubert, Didier Surdez, Olivier Delattre, Claire Wilhelm, Jean-Louis Viovy
Pubblicato in: Lab on a Chip, 2024, ISSN 1473-0189
Editore: Royal Society of Chemistry
DOI: 10.1101/2023.05.16.540960

Magnetic Compression of Tumor Spheroids Increases Cell Proliferation In Vitro and Cancer Progression In Vivo.

Autori: Mary, Gaëtan; Malgras, Brice; Perez, Jose Efrain; Nagle, Irène; Luciani, Nathalie; Pimpie, Cynthia; Asnacios, Atef; Pocard, Marc; Reffay, Myriam; Wilhelm, Claire; Perez, Jose,
Pubblicato in: Cancers, Numero Vol 14, Iss 366, p 366, 2022, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14020366

Massive Intracellular Remodeling of CuS Nanomaterials Produces Nontoxic Bioengineered Structures with Preserved Photothermal Potential.

Autori: Alberto Curcio; Alberto Curcio; Aurore Van de Walle; Aurore Van de Walle; Emilia Benassai; Aida Serrano; Nathalie Luciani; Nicolas Menguy; Bella B. Manshian; Ara Sargsian; Stefaan J. Soenen; Ana Espinosa; Ana Espinosa; Ali Abou-Hassan; Claire Wilhelm; Claire Wilhelm
Pubblicato in: ACS nano, Numero 1, 2021, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.1c00567

In Vivo Assimilation of CuS, Iron Oxide and Iron Oxide@CuS Nanoparticles in Mice: A 6-Month Follow-Up Study

Autori: Alberto Curcio; Aurore Van de Walle; Christine Péchoux; Ali Abou-Hassan; Claire Wilhelm
Pubblicato in: Pharmaceutics, Numero 1, 2022, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14010179

The role of tumor model in magnetic targeting of magnetosomes and ultramagnetic liposomes

Autori: Alberto Curcio; Jose Efrain Perez; Sandra Prévéral; Alexandre Fromain; Coralie Genevois; Aude Michel; Aurore Van de Walle; Yoann Lalatonne; Damien Faivre; Christine Ménager; Claire Wilhelm
Pubblicato in: Scientific Reports, Numero 1, 2023, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-023-28914-4

Chemo–Phototherapeutic Effect of Polyoxometalate-Stabilized Gold Nanostars for Cancer Treatment

Autori: Juan F. Ramirez Henao, Souhir Boujday, Claire Wilhelm, Basile Bouvet, Somia Tomane, Ioanna Christodoulou, Daoming Sun, Guilhem Cure, Ferdaous Ben Romdhane, Antoine Miche, Anne Dolbecq, Pierre Mialane, Anne Vallée
Pubblicato in: ACS Applied Nano Materials, Numero 7, 2024, Pagina/e 21094-21103, ISSN 2574-0970
Editore: American Chemical Society (ACS)
DOI: 10.1021/acsanm.4c04277

Magnetite Nanoparticle Photothermal Therapy in a Pancreatic Tumor-on-Chip: A Dual-Action Approach Targeting Cancer Cells and their Microenvironment

Autori: Anastasiia Dubrova, Charles Cavaniol, Aurore Van de Walle, Paul Mathieu, Zoé Fusilier, Nader Yaacoub, Yoann Lalatonne, Stephanie Descroix, Claire Wilhelm
Pubblicato in: ACS Nano, Numero 19, 2025, Pagina/e 19790-19805, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.5c02099

Multiscale Thermal Analysis of Gold Nanostars in 3D Tumor Spheroids: Integrating Cellular‐Level Photothermal Effects and Nanothermometry via X‐Ray Spectroscopy

Autori: Rosalía López‐Méndez, Anastasiia Dubrova, Javier Reguera, Rául Magro, Fátima Esteban‐Betegón, Ana Parente, Miguel Ángel García, Julio Camarero, Emiliano Fonda, Claire Wilhelm, Álvaro Muñoz‐Noval, Ana Espinosa
Pubblicato in: Advanced Healthcare Materials, Numero 14, 2025, ISSN 2192-2640
Editore: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202403799

Vascularized tumor models for the evaluation of drug delivery systems: a paradigm shift

Autori: Elliot Lopez-Vince, Claire Wilhelm, Teresa Simon-Yarza
Pubblicato in: Drug Delivery and Translational Research, Numero 14, 2024, Pagina/e 2216-2241, ISSN 2190-393X
Editore: Springer Pub. Co.,
DOI: 10.1007/s13346-024-01580-3

A polysaccharide-based hydrogel platform for tumor spheroid production and anticancer drug screening

Autori: Elliot Lopez-Vince, Teresa Simon-Yarza, Claire Wilhelm
Pubblicato in: Scientific Reports, Numero 15, 2025, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-025-87896-7

Emergence of magnetic nanoparticles in photothermal and ferroptotic therapies

Autori: Aurore Van de Walle, Albert Figuerola, Ana Espinosa, Ali Abou-Hassan, Marta Estrader, Claire Wilhelm
Pubblicato in: Materials Horizons, Numero 10, 2024, Pagina/e 4757-4775, ISSN 2051-6347
Editore: Royal Society of Chemistry (RSC)
DOI: 10.1039/d3mh00831b