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Fine tune of cellular behavior: multifunctional materials for medical implants

Project description

Encouraging the triumph of good over evil

Whenever an implant or medical device is inserted in our body, a race for the surface takes place between ‘good‘ eukaryotic cells of our tissues and ‘evil‘ bacteria. In this competitive scenario, the winner takes it all. If bacteria reach first the surface, the success of the implant will be compromised. A possible solution to this problem would be the use of antibiotics. While have revolutionised medicine and our ability to combat bacteria, antibiotics and more generally antibacterial or cytotoxic substances can also inhibit the functioning of healthy cells. The big question is: how can we enhance the adhesion and integration of ‘good‘ healthy cells while simultaneously preventing the formation of ‘evil‘ bacterial biofilms? The EU-funded Bio-TUNE project is addressing these two antagonistic goals with thorough characterisation of eukaryotic and bacterial competition. Insight will aid in development of selective coatings for implants that encourage healthy tissue growth while impeding bacterial colonisation.

Call for proposal

H2020-MSCA-RISE-2019
See other projects for this call

Funding Scheme

MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE)

Coordinator

UNIVERSITAT POLITECNICA DE CATALUNYA
Address
Calle Jordi Girona 31
08034 Barcelona
Spain
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 216 200

Participants (5)

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany
EU contribution
€ 87 400
Address
Hofgartenstrasse 8
80539 Muenchen
Activity type
Research Organisations
UNIVERSITY OF BRISTOL
United Kingdom
EU contribution
€ 110 400
Address
Beacon House Queens Road
BS8 1QU Bristol
Activity type
Higher or Secondary Education Establishments
UNIVERSITA DEGLI STUDI DI CAMERINO
Italy
EU contribution
€ 211 600
Address
Piazza Cavour 19F
62032 Camerino
Activity type
Higher or Secondary Education Establishments
UNIVERSITY OF GLASGOW
United Kingdom
EU contribution
€ 110 400
Address
University Avenue
G12 8QQ Glasgow
Activity type
Higher or Secondary Education Establishments
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
EU contribution
€ 78 200
Address
Rue De Tolbiac 101
75654 Paris
Activity type
Research Organisations

Partners (4)

UNIVERSITI SAINS MALAYSIA*
Malaysia
Address
Minden
11800 Penang
Activity type
Higher or Secondary Education Establishments
UNIVERSIDAD NACIONAL DE GENERAL SAN MARTIN
Argentina
Address
Martin De Irigoyen 3100
1650 San Martin Buenos Aires
Activity type
Higher or Secondary Education Establishments
GADJAH MADA UNIVERSITY
Indonesia
Address
Bulaksumur
55281 Yogyakarta
Activity type
Higher or Secondary Education Establishments
UNIVERSIDAD PERUANA DE CIENCIAS APLICADAS SAC
Peru
Address
Av Alonso De Molina 1611 Santiago De Surco
33 Lima
Activity type
Higher or Secondary Education Establishments