Project description
Studying the exposome for healthier future for all children
Mental health is the result of the complex interplay between genetic, psychological, environmental and other factors and experiences. The exposome concept, referring to the totality of exposures from conception onwards, is emerging as a very promising approach in studying the role of the environment in human disease. The EU-funded Equal-Life project will develop and utilise the exposome concept in an integrated study of the external exposome and its social aspects and of measurable internal physiological factors and link those to a child's development and life course mental health. This will be done using a novel approach combining exposure data to characterise, measure, model and understand influences at different developmental stages. The goal is to propose the best supportive environments for all children.
Objective
EQUAL-LIFE will develop and test combined exposure data using a novel approach to multi-modal exposures and their impact on children’s mental health and development. A combination of birth-cohort data with new sources of data, will provide insight into aspects of physical and social exposures hitherto untapped. It will do this at different scale levels and timeframes, while accounting for the distribution of exposures in social groups based on gender, ethnicity, social vulnerability.
Beginning with child development and mental health, a set of theory-based questions is formulated, a wide range of relevant environmental and social hazards is defined and validated at the stakeholders end. Exposure assessment combines traditional GIS-based approaches with omics approaches and new sources of data that could explain aspects of the urban environment at a higher spatial and temporal granularity, and provide insight into untapped parameters relating to exposure (spatial quality of neighborhoods). These together form the early-life exposome. Statistical tools integrate data at different scale levels and times and combine e.g. machine learning, causal models with subgroups measures.
EQUAL-LIFE uses data from birth-cohorts, longitudinal school data sets and cross-sectional studies (N=>250.000) including data on exposures, biomarkers, mental health and developmental outcomes, in their social context.
EQUAL-LIFE contributes to the development/utilization of the exposome concept by 1) integrating the internal, external and social exposome 2) by studying a distinct set of effects on a child’s development and mental health 3) by characterizing/measuring/modelling the child’s environment at different stages and activity spaces 4) by looking at supportive environments for child development, rather than merely pollutants 5) by combining physical, social indicators with novel biomarkers and using new data sources describing child activity patterns and environments.
EQUAL-LIFE is part of the European Human Exposome Network comprised of nine projects selected from this same call.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being
MAIN PROGRAMME
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H2020-EU.3.1.2. - Preventing disease
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
RIA - Research and Innovation action
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-SC1-BHC-2018-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
3721 MA Bilthoven
Netherlands
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Participants (22)
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405 30 Goeteborg
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70211 KUOPIO
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LE1 7RH Leicester
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28359 Bremen
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2628 CN DELFT
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171 77 STOCKHOLM
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6955 AM Ellecom
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
1000 Ljubljana
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08036 Barcelona
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67663 Kaiserslautern
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9000 GENT
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00014 HELSINGIN YLIOPISTO
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5612 AE Eindhoven
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58093 Hagen
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.
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1000 Skopje
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8010 Graz
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52062 Aachen
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3521 AZ Utrecht
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The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
22066 Mariano Comense
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
5037 DA TILBURG
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43003 Tarragona
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
SW17 0RE London
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The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.