Impact of exposome on the course of lung diseases

Informazioni relative al progetto

REMEDIA

ID dell’accordo di sovvenzione: 874753

DOI

10.3030/874753

Progetto chiuso

Data della firma CE 6 Dicembre 2019

Data di avvio 1 Gennaio 2020

Data di completamento 30 Giugno 2025

Finanziato da

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Costo totale

€ 11 013 022,14

Contributo UE

€ 11 013 022,14

Coordinato da

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (1)

Atmosphere type

Simulation of chosen atmospheres characteristics (which cities or environments?)

Other (3)

Intellectual property workshop

IP workshop delivered by a TTO from Inserm transfert on results sharing, ect...

Website, logo and communication tools

website, logo and communications tools (brochure, slide lay out etc... )for the project.

EU member states exposome mapping

Presentation of risk assessment levels in a European map

Demonstrators, pilots, prototypes (1)

AQ protocols

Definition of Atmospheric Characterization Protocols to qualify/quantify Air Quality of the exposome.

Pubblicazioni

Peer reviewed articles (23)

Cardiopulmonary Mortality and Fine Particulate Air Pollution by Species and Source in a National U.S. Cohort. Environ Sci Technol

Autori: Pond ZA, Hernandez CS, Adams PJ, Pandis SN, Garcia GR, Robinson AL, Marshall JD, Burnett R, Skyllakou K, Garcia Rivera P, Karnezi E, Coleman CJ, Pope CA 3rd
Pubblicato in: Environ Sci Technol, 2022, ISSN 0013-936X
Editore: American Chemical Society
DOI: 10.1021/acs.est.1c04176

Secondary aerosol formation during the dark oxidation of residential biomass burning emissions

Autori: Kodros JK, Kaltsonoudis C, Paglione M, Florou K, Jorga S, Vasilakopoulou C, Cirtog M, Cazaunau M, Picquet-Varrault B, Nenes A, Pandis SN
Pubblicato in: Environmental science : atmospheres, 2022, ISSN 2634-3606
Editore: Royal Society of Chemistry
DOI: 10.1039/d2ea00031h

High-Resolution Downscaling of Source Resolved PM2.5 Predictions Using Machine Learning Models

Autori: Brian T. Dinkelacker, Pablo Garcia Rivera, Julian D. Marshall, Peter J. Adams Spyros N. Pandis
Pubblicato in: Atmospheric Environment, 2023, ISSN 1352-2310
Editore: Elsevier BV
DOI: 10.1016/j.atmosenv.2023.119967

Impact of COVID-19 Lockdown on Oxidative Potential of Particulate Matter: Case of Athens (Greece)

Autori: Despina Paraskevopoulou; Aikaterini Bougiatioti; Pavlos Zarmpas; Maria Tsagkaraki; Athanasios Nenes; Nikolaos Mihalopoulos
Pubblicato in: Toxics; Volume 10; Numero 6; Pages: 280, Numero 1, 2022, ISSN 2305-6304
Editore: MDPI
DOI: 10.3390/toxics10060280

Source-specific air pollution and risk of chronic obstructive pulmonary disease: A pooled cohort study

Autori: Manuella Lech Cantuaria, Aslak Harbo Poulsen, Ole Raaschou-Nielsen, Étienne Audureau, Ralph Epaud, Sophie Lanone, Jørgen Brandt, Lisa Marie Frohn, Matthias Ketzel, Anja Olsen, Lau Caspar Thygesen, Mette Sørensen
Pubblicato in: Environmental Health Perspectives, 2025, ISSN 0091-6765
Editore: US Department of Health and Human Services
DOI: 10.1289/ehp16554

724 Uncovering of people with CF and exposome associations through unsupervised multidimensional phenotyping

Autori: M. Leemans, Y. Bousserrhine, P. de Carli, C. Dehillotte, T. Benoussaid, A. Coman, I. Coll, S. Lanone, R. Epaud, E. Audureau
Pubblicato in: Journal of Cystic Fibrosis, Numero 23, 2025, Pagina/e S409, ISSN 1569-1993
Editore: Elsevier BV
DOI: 10.1016/s1569-1993(24)01562-5

Characterization and dark oxidation of the emissions of a pellet stove

Autori: Kalliopi Florou, John K. Kodros, Marco Paglione, Spiro Jorga, Stefania Squizzato, Mauro Masiol, Petro Uruci, Athanasios Nenes, Spyros N. Pandis
Pubblicato in: Environmental Science : Atmospheres, 2023, ISSN 2634-3606
Editore: Royal Society of Chemistry
DOI: 10.1039/d3ea00070b

Impact of a rare respiratory diseases reference centre set-up on primary ciliary dyskinesia care pathway. Eur Respir J

Autori: Epaud S, Epaud R, Salaün-Penquer N, Belozertseva E, Remus N, Douvry B, Bequignon E, Coste A, Prulière-Escabasse V, Schlemmer F, Jung C, Ortala M, Maitre B, Delestrain C.
Pubblicato in: European Respiratory Journal, 2021, ISSN 0903-1936
Editore: European Respiratory Society
DOI: 10.1183/13993003.02413-2021

Acute exposure to realistic simulated urban atmospheres exacerbates pulmonary phenotype in cystic fibrosis-like mice.

Autori: Blayac M, Yegen CH, Marj EA, Rodriguez JCM, Cazaunau M, Bergé A, Epaud R, Coll P, Lanone S
Pubblicato in: Journal of Hazardous Materials, 2024, Pagina/e 133340, ISSN 0304-3894
Editore: Elsevier BV
DOI: 10.1016/j.jhazmat.2023.133340

Associations between prenatal exposure to outdoor PM2.5 and NO2 and childhood respiratory symptoms

Autori: A R Patlan Hernandez, E Audureau, C Monfort, R Epaud, S Lanone, M Nieuwenhuijsen, M de Castro, C Warembourg, C Chevrier, B Jacquemin
Pubblicato in: European Journal of Public Health, Numero 33, 2023, ISSN 1101-1262
Editore: Oxford University Press
DOI: 10.1093/eurpub/ckad160.030

Air pollution as an early determinant of COPD. European Respiratory Review.

Autori: Lu Z, Coll P, Maitre B, Epaud R, Lanone S
Pubblicato in: European Respiratory Review, 2022, ISSN 0905-9180
Editore: European Respiratory Society
DOI: 10.1183/16000617.0059-2022

An Efficient Low‐Cost Device for Sampling Exhaled Breath Condensate EBC

Autori: Mehran Khorshid, Soroush Bakhshi Sichani, Dimna L. Barbosa Estrada, Werner Neefs, Alexander Clement, Gerhard Pohlmann, Ralph Epaud, Sophie Lanone, and Patrick Wagner
Pubblicato in: Advanced Sensor Research, 2023, ISSN 2751-1219
Editore: WILEY
DOI: 10.1002/adsr.202400020

The Impact of Air Pollution on the Course of Cystic Fibrosis: A Review. Front. Physiol.

Autori: Blayac M, Coll P, Urbach V, Fanen P, Epaud R and Lanone S
Pubblicato in: Frontiers in Physiology, 2022, ISSN 1664-042X
Editore: Frontiers Research Foundation
DOI: 10.3389/fphys.2022.908230

Assessing the impact of exposome on the course of chronic obstructive pulmonary disease and cystc fibrosis

Autori: Manon Benjdir, Étienne Audureau, Ariel Beresniak, Patrice Coll, Ralph Epaud, Kristina Fiedler, Bénédicte Jacquemin, Laurent Niddam, Spyros N. Pandis, Gerhard Pohlmann, Torkjel M. Sandanger, Kai Simmons, Mette Sørensen, Patrick Wagner, Sophie Lanone
Pubblicato in: Environmental Epidemiology, Numero 5/4, 2021, Pagina/e e165, ISSN 2474-7882
Editore: Wolters Kluwer Health, Inc.
DOI: 10.1097/ee9.0000000000000165

Wildfire and African dust aerosol oxidative potential, exposure and dose in the human respiratory tract

Autori: Maria Mylonaki, Maria Gini, Maria Georgopoulou, Marika Pilou, Eleftheria Chalvatzaki, Stavros Solomos, Evangelia Diapouli, Elina Giannakaki, Mihalis Lazaridis, Spyros N. Pandis, Athanasios Nenes, Konstantinos Eleftheriadis, Alexandros Papayannis
Pubblicato in: Science of The Total Environment, Numero 913, 2024, Pagina/e 169683, ISSN 0048-9697
Editore: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.169683

The REMEDIA European Project Approach

Autori: Benjdir, Manon; Audureau, Étienne; Beresniak, Ariel; Coll, Patrice; Epaud, Ralph; Fiedler, Kristina; Jacquemin, Bénédicte; Niddam, Laurent; Pandis, Spyros N.; Pohlmann, Gerhard; Sandanger, Torkjel M.; Simmons, Kai; Sørensen, Mette; Wagner, Patrick; Lanone, Sophie
Pubblicato in: Environmental Epidemiology, Numero 1, 2021, ISSN 2474-7882
Editore: Europe PMC
DOI: 10.1097/ee9.0000000000000165

A coupled atmospheric simulation chamber system for the production of realistic aerosols and preclinical model exposure

Autori: Maria P. Georgopoulou, Juan Camilo Macias Rodriguez, Céline-Hivda Yegen, Christos Kaltsonoudis, Mathieu Cazaunau, Christina N. Vasilakopoulou, Angeliki Matrali, Katerina Seitanidi, Andreas Aktypis, Athanasios Nenes, Clément Buissot, Aline Gratien, Antonin Berge, Edouard Pangui, Elie Al Marj, Lucy Gerard, Bénédicte Picquet Varrault, Sophie Lanone, Patrice Coll, Spyros N. Pandis
Pubblicato in: Air Quality, Atmosphere & Health, Numero 17, 2024, Pagina/e 2909-2930, ISSN 1873-9318
Editore: Springer Verlag
DOI: 10.1007/s11869-024-01611-5

Source-Resolved Variability of Fine Particulate Matter and Human Exposure in an Urban Area

Autori: P. Garcia Rivera; B. T. Dinkelacker; I. Kioutsioukis; P. J. Adams; P. J. Adams; S. N. Pandis; S. N. Pandis
Pubblicato in: Atmospheric Chemistry and Physics, Vol 22, Pp 2011-2027 (2022), Numero 1, 2022, ISSN 1680-7324
Editore: Copernicus GmbH
DOI: 10.5194/acp-2021-568

Impact d’un pré-conditionnement à de l’anxiété suivi d’une exposition à la pollution atmosphérique sur la physiopathologie de la mucoviscidose

Autori: C.-H. Yegen, C. Boucheniata, M. Bourenane, C. Macias, C. Buissot, M. Georgopoulos, M. Cazaunau, A. Bergé, A. Der Vartanian, R. Souktani, R. Epaud, S.N. Pandis, P. Coll, S. Lanone
Pubblicato in: Revue des Maladies Respiratoires, Numero 42, 2025, Pagina/e 130-133, ISSN 0761-8425
Editore: Elsevier Masson
DOI: 10.1016/j.rmr.2025.02.004

Effects of residential greenness during pregnancy on childhood asthma, rhinitis, eczema, and their comorbidity: findings from the French mother-child cohort Pélagie

Autori: Alan R. Patlán-Hernández, Christine Monfort, Etienne Audureau, Marta Cirach, Ralph Epaud, Kees de Hoogh, Sophie Lanone, Parisa Montazeri, Danielle Vienneau, Charline Warembourg, Cécile Chevrier, Marine Savouré, Bénédicte Jacquemin
Pubblicato in: Environmental Research, Numero 279, 2025, Pagina/e 121730, ISSN 0013-9351
Editore: Academic Press
DOI: 10.1016/j.envres.2025.121730

Associations of exposure to outdoor PM2.5 and NO2 during pregnancy with childhood asthma, rhinitis, and eczema in a predominantly rural French mother-child cohort

Autori: Alan R. Patlán-Hernández, Marine Savouré, Etienne Audureau, Christine Monfort, Montserrat de Castro, Ralph Epaud, Kees de Hoogh, Ian Hough, Itai Kloog, Sophie Lanone, Johanna Lepeule, Mark Nieuwenhuijsen, Danielle Vienneau, Charline Warembourg, Cécile Chevrier, Bénédicte Jacquemin
Pubblicato in: Environmental Pollution, Numero 363, 2024, Pagina/e 125206, ISSN 0269-7491
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.envpol.2024.125206

Impact of the COVID-19 pandemic and associated lockdown measures on the management, health, and behavior of the cystic fibrosis population in France during 2020 (MUCONFIN).

Autori: Oubaya N, Pombet T, Delestrain C, Remus N, Douvry B, Grenet D, Corvol H, Thouvenin G, Prulière-Escabasse V, Mounir H, Argoud D, Fretigne C, Costes L, Mackiewicz MP, Jung C, Ahamada L, Lanone S, Maitre B, Bégot AC, Epaud R.
Pubblicato in: Frontiers in public health, 2022, ISSN 2296-2565
Editore: Frontiers
DOI: 10.3389/fpubh.2022.978627

Uncovering cystic fibrosis patient profiles and exposome associations through unsupervised multidimensional phenotyping

Autori: M. Leemans, R. Epaud, P. De Carli, C. Dehillotte, L. Lemonnier, T. Benoussaid, A. Coman, I. Coll, S. Lanone, E. Audureau
Pubblicato in: Revue des Maladies Respiratoires, Numero 41, 2024, Pagina/e 200, ISSN 0761-8425
Editore: Elsevier Masson
DOI: 10.1016/j.rmr.2024.01.038

Thesis and dissertations (3)

Impact des expositions précoces à la pollution atmosphérique sur la maturation pulmonaire et la susceptibilité à développer une BPCO : une étude expérimentale

Autori: Buissot Clément
Pubblicato in: 2025
Editore: Université Paris Est-Créteil

An impedimetric, MIP-based sensor for 3-NT detection in exhaled breath condensate of lung patients

Autori: Lukas NYS
Pubblicato in: 2023
Editore: KU Leuven

A highly sensitive MIP and aptamer-based biosensor for the detection of lung disease biomarkers in exhaled breath condensate

Autori: Dimna Lilia BARBOSA ESTRADA
Pubblicato in: 2024
Editore: KU Leuven

Other (2)

Evaluation longitudinale de l'activite du canal cftr : modèle de sécretion salivaire chez la souris

Autori: Blayac M, Souktani R, Urbach V, Lanone S
Pubblicato in: Tr@smettreRIF, 2023
Editore: UPEC

Evaluation of high-resolution predictions of fine particulate matter and its composition in an urban area using PMCAMx-v2.0 Geosci

Autori: Brian T. Dinkelacker, Rivera PG, Kioutsioukis I, Adams PJ, Pandis S.
Pubblicato in: Geoscientific Model Development, 2022
Editore: European Geosciences Union
DOI: 10.5194/gmd-15-8899-2022