Monitoring multidimensional aspects of QUAlity of Life after cancer ImmunoTherapy - an Open smart digital Platform for personalized prevention and patient management

Informazioni relative al progetto

QUALITOP

ID dell’accordo di sovvenzione: 875171

DOI

10.3030/875171

Progetto chiuso

Data della firma CE 28 Ottobre 2019

Data di avvio 1 Gennaio 2020

Data di completamento 30 Giugno 2024

Finanziato da

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Costo totale

€ 5 196 772,50

Contributo UE

€ 5 196 772,50

Coordinato da

HOSPICES CIVILS DE LYON
France

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (18)

Report on Workshop 1

Report presenting the discussions and outcomes of the first dissemination workshop organised by ECPC with pharmaceutical industry.

Digital dexterity program & digital data-centric transformation strategy

Digital dexterity program digital datacentric transformation strategy

Identification and formalization of prediction and recommendation rules
Qualitative Causal Loop Diagram

A qualitative causal loop diagram to present how QoL is affected by various variables and feedback loops

Design of analysis and prediction algorithms based on information fusion
Report on Workshop 2

Report on discussions and outcomes of workshop 2 organised by ECPC with cancer patients organisations

Specification and development of the visualization and data exploration interface by physicians
Development of the monitoring process based on data flow analysis and information correlation
Press release kit for the launch of the project.
Dissemination, Exploitation and Communication Strategy

Preliminary descriptino of envisaged key communication, dissemination actions, and envisaged exploitation strategy

Identification and qualification of data necessary for monitoring
Architectural requirements and specification of the Smart Digital Medical Platform
Design & Implementation Medical Interoperability Language

Design Implementation Medical Interoperability Language

Map of existing databases & cohorts

Map of existing databases cohorts

Report on the IR-AEs following cancer immunotherapy

Report on the IRAEs following cancer immunotherapy

Test component algorithms developed on real-world datasets

Test component algorithms developed on realworld datasets

Validated QoL questionnaires

Validated QoL questionnaires with specific adhoc items for cancer patients treated with immunotherapy CPI and CAR Tcells

Guidelines related to Data Protection and Security

Public guidelines to describe the data protection Policy and security measures put in place by the project

Open Research Data Pilot (1)

Data Management Plan

Websites, patent fillings, videos etc. (1)

Project website

Project public website online, including project description, goals, consortium and news section.

Pubblicazioni

Peer reviewed articles (8)

An Overview of Regression Models for Adverse Events Analysis

Autori: Elsa Coz, Mathieu Fauvernier, Delphine Maucort-Boulch
Pubblicato in: Drug Safety, Numero 47, 2024, Pagina/e 205-216, ISSN 0114-5916
Editore: Adis International Ltd.
DOI: 10.1007/s40264-023-01380-7

Monitoring multidimensional aspects of quality of life after cancer immunotherapy: protocol for the international multicentre, observational QUALITOP cohort study

Autori: Petra C. Vinke, Marc Combalia, Geertruida H de Bock, Clémence Leyrat, Anne Mea Spanjaart, Stephane Dalle, Maria Gomes da Silva, Aurore Fouda Essongue, Aurélie Rabier, Myriam Pannard, Mohammad S Jalali, Amal Elgammal, Mike Papazoglou, Mohand-Said Hacid, Catherine Rioufol, Marie-José Kersten, Martijn GH van Oijen, Erick Suazo-Zepeda, Ananya Malhotra, Emmanuel Coquery, Amélie Anota, Marie Preau,
Pubblicato in: BMJ Open, Numero 13, 2023, Pagina/e e069090, ISSN 2044-6055
Editore: BMJ Publishing Group
DOI: 10.1136/bmjopen-2022-069090

The association of nutritional and inflammatory biomarkers with overall survival in patients with non‐small‐cell lung cancer treated with immune checkpoint inhibitors

Autori: I. M. Horstman, P. C. Vinke, E. Suazo‐Zepeda, T. J. N. Hiltermann, M. A. Heuvelmans, E. Corpeleijn, G. H. de Bock
Pubblicato in: Thoracic Cancer, Numero 15, 2024, Pagina/e 1764-1771, ISSN 1759-7706
Editore: Blackwell Publishing Asia Pty Ltd
DOI: 10.1111/1759-7714.15401

The Dutch CAR-T Tumorboard Experience: Population-Based Real-World Data on Patients with Relapsed or Refractory Large B-Cell Lymphoma Referred for CD19-Directed CAR T-Cell Therapy in The Netherlands

Autori: Anne M. Spanjaart, Elise R. A. Pennings, Pim G. N. J. Mutsaers, Suzanne van Dorp, Margot Jak, Jaap A. van Doesum, Janneke W. de Boer, Anne G. H. Niezink, Milan Kos, Joost S. P. Vermaat, Aniko Sijs-Szabo, Marjolein W. M. van der Poel, Inger S. Nijhof, Maria T. Kuipers, Martine E. D. Chamuleau, Pieternella J. Lugtenburg, Jeanette K. Doorduijn, Yasmina I. M. Serroukh, Monique C. Minnema, Tom van Meer
Pubblicato in: Cancers, Numero 15, 2023, Pagina/e 4334, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers15174334

Associations between treatments, comorbidities and multidimensional aspects of quality of life among patients with advanced cancer in the Netherlands—a 2017–2020 multicentre cross-sectional study

Autori: Ananya Malhotra, Heidi P. Fransen, Manuela Quaresma, Natasja Raijmakers, Moyke A. J. Versluis, Bernard Rachet, Marissa C. van Maaren, Clémence Leyrat
Pubblicato in: Quality of Life Research, Numero 32, 2023, Pagina/e 3123-3133, ISSN 0962-9343
Editore: Kluwer Academic Publishers
DOI: 10.1007/s11136-023-03460-8

Quality-of-Life Assessment in Spanish Stage III Immunotherapy Patients: A Prospective Observational Study

Autori: F. Crespí-Payeras, M. Luque-Luna, M. Gracia-Rius, P. Iglesias, D. Rizo, C. Carrera, S. Podlipnik, J. Malvehy, S. Puig
Pubblicato in: EJC Skin Cancer, Numero 2, 2024, Pagina/e 100162, ISSN 2772-6118
Editore: ELSEVIER
DOI: 10.1016/j.ejcskn.2024.100162

Quality of life after treatment with immune checkpoint inhibitors for lung cancer; the impact of age

Autori: E. Suazo-Zepeda, P.C. Vinke, M.A. Heuvelmans, G. Sidorenkov, T.J.N. Hiltermann, G.H. de Bock
Pubblicato in: Lung Cancer, Numero 176, 2024, Pagina/e 89-97, ISSN 0169-5002
Editore: Elsevier BV
DOI: 10.1016/j.lungcan.2022.12.017

Access control based on entity matching for secure data sharing

Autori: Juba Agoun & Mohand-Saïd Hacid
Pubblicato in: Springer Link, 2022, ISSN 1863-2386
Editore: Springer Verlag
DOI: 10.1007/s11761-021-00331-3

Conference proceedings (3)

Autoencoder-based Attribute Noise Handling Method for Medical Data

Autori: Thomas Ranvier, Haytham Elgazel, Emmanuel Coquery and Khalid Benabdeslem
Pubblicato in: The 29th International Conference on Neural Information Processing, 2022
Editore: ICONIP 2022

Development of a Core Set of Patient- and Caregiver-Reported Signs and Symptoms to Facilitate Early Recognition of Acute Chimeric Antigen Receptor T-Cell Therapy Toxicities

Autori: Anne M Spanjaart , Elise R A Pennings, Milan Kos, Pim G N J Mutsaers, Pieternella J Lugtenburg, Tom van Meerten, Jaap A van Doesum 7, Monique C Minnema, Margot Jak, Suzanne van Dorp, Joost S P Vermaat, Marjolein W M van der Poel, Martijn G H van Oijen, Maria T Kuipers, Inger S Nijhof, Marie José Kersten
Pubblicato in: American Society of Clinical Oncology, 2022
Editore: JCO Oncol Practice
DOI: 10.1200/op.22.00501

Deduplication Over Heterogeneous Attribute Types (D-HAT)

Autori: Loujain Liekah, George Papadakis
Pubblicato in: Advanced Data Mining and Applications: 18th International Conference, ADMA 2022,, 2022, Pagina/e 379–391
Editore: LNAI,volume 13726
DOI: 10.1007/978-3-031-22137-8_28

Book chapters (1)

A Reference Architecture for Smart Digital Platform for Personalized Prevention and Patient Management

Autori: Amal Elgammal, Bernd J. Krämer
Pubblicato in: Next-Gen Digital Services. A Retrospective and Roadmap for Service Computing of the Future - Essays Dedicated to Michael Papazoglou on the Occasion of His 65th Birthday and His Retirement, Numero 12521, 2021, Pagina/e 88-99, ISBN 978-3-030-73202-8
Editore: Springer International Publishing
DOI: 10.1007/978-3-030-73203-5_7